Bipolar Disorder Quiz: Mania to Depression

1. What is the primary diagnostic difference between Bipolar I and Bipolar II disorder?

Bipolar I includes at least one manic episode; Bipolar II includes hypomanic episodes and major depression

Bipolar I is more common in women; Bipolar II is more common in men

Bipolar I responds better to lithium; Bipolar II does not

Bipolar I has rapid cycling; Bipolar II has slow cycling

2. During a manic episode, which of the following symptoms is NOT typically observed?

Decreased need for sleep

Grandiosity and inflated self-esteem

Persistent depressed mood lasting weeks

Racing thoughts and flight of ideas

3. A hypomanic episode differs from a manic episode in that it:

Lasts at least 7 days instead of 3 days

Does not cause significant functional impairment and no psychotic features

Includes delusions and hallucinations

Only occurs in females

4. Which neurotransmitter system is most implicated in the pathophysiology of bipolar disorder?

Serotonin alone

Monoamine dysregulation (serotonin, dopamine, norepinephrine)

GABA exclusively

Acetylcholine primarily

5. Lithium is effective in treating bipolar disorder primarily because it:

Increases dopamine production

Modulates second-messenger systems and neuroprotection

Blocks all neurotransmission

Increases rapid eye movement sleep

6. Which of the following is a recognized risk factor for developing bipolar disorder?

Genetic predisposition and family history

High socioeconomic status only

Living in urban areas exclusively

Late-onset anxiety disorders

7. Rapid cycling in bipolar disorder is defined as having how many or more mood episodes per year?

Two

Three

Four

Six

8. Which mood stabilizer requires regular blood monitoring due to a narrow therapeutic window?

Valproate

Lithium

Lamotrigine

Quetiapine

9. Antidepressants in bipolar disorder treatment carry a risk of:

Triggering manic or hypomanic episodes

Permanent mood stabilization

Eliminating all depressive symptoms

Reducing the need for mood stabilizers

10. The prodromal symptoms of a manic episode often include:

Decreased energy and social withdrawal

Increased goal-directed activity and reduced sleep need

Persistent anhedonia

Suicidal ideation

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13. Bipolar disorder typically first manifests during which developmental period?

Early childhood (ages 3–7)

Late adolescence to early adulthood (ages 15–25)

Middle adulthood (ages 40–50)

Late adulthood (ages 60+)

14. Sleep disruption in bipolar mania is characterized by:

Increased sleep duration with poor quality

Decreased need for sleep without feeling rested

Excessive daytime somnolence

Sleep paralysis episodes

15. Which atypical antipsychotic is FDA-approved for maintenance treatment of bipolar I disorder?