Zimnic O / Balofox

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Quizzes Created: 14 | Total Attempts: 6,259
Questions: 10 | Attempts: 122

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Zimnic O / Balofox - Quiz

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Questions and Answers
  • 1. 

    Can an Aminoglycoside or a Fluroquinolone be given for women suffering from Pyelonephritis needing hospitilization ?

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Aminoglycosides and fluoroquinolones can be given to women suffering from pyelonephritis who require hospitalization. These antibiotics are commonly used to treat severe urinary tract infections, including pyelonephritis, as they have a broad spectrum of activity against the bacteria that cause these infections. However, the choice of antibiotic should always be based on the individual patient's medical history, allergies, and susceptibility of the bacteria causing the infection. It is important to consult a healthcare professional for proper diagnosis and treatment.

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  • 2. 

    The addition of which group has made the molecule Balofloxacin more effective  with less dose compared to other quinolones?

    • A.

      Methoxy group

    • B.

      Pipperidin group

    • C.

      N1 cyclo propyl ring

    • D.

      All the above three

    Correct Answer
    C. N1 cyclo propyl ring
    Explanation
    The addition of the N1 cyclo propyl ring has made the molecule Balofloxacin more effective with less dose compared to other quinolones.

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  • 3. 

    The UTI causing pathogen S.Saprophyticus is

    Correct Answer
    Gram positive aerobic bacteria
    Explanation
    The given correct answer states that the UTI causing pathogen S.Saprophyticus is a Gram positive aerobic bacteria. This means that the bacteria can retain the crystal violet stain during the Gram staining process, indicating a thick peptidoglycan layer in its cell wall. Additionally, being aerobic implies that it requires oxygen for growth and metabolism. Therefore, S.Saprophyticus is a Gram positive aerobic bacteria.

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  • 4. 

    The MIC of Cefixime in the Cefixime + Ofloxacin combination against S.Typhi (Invitro MIC Study)is

    • A.

      0.01 mcg/ml

    • B.

      0.10 mcg /ml

    • C.

      0.001 mcg /ml

    • D.

      0.11 mcg /ml

    Correct Answer
    A. 0.01 mcg/ml
    Explanation
    The MIC (Minimum Inhibitory Concentration) of Cefixime in the Cefixime + Ofloxacin combination against S.Typhi (Invitro MIC Study) is 0.01 mcg/ml. This means that the concentration of Cefixime required to inhibit the growth of S.Typhi in vitro is 0.01 mcg/ml.

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  • 5. 

    Does DCGI recommend Cefixime+Ofloxacin combination in UTI

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    The answer is true because the Drug Controller General of India (DCGI) does recommend the combination of Cefixime and Ofloxacin for the treatment of urinary tract infections (UTIs). This combination is commonly used and effective in treating UTIs caused by certain bacteria. It is important to note that this recommendation may vary based on individual patient factors and the specific guidelines of healthcare professionals.

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  • 6. 

    The result of the PMS study on Zimnic O states that

    • A.

      The combination is 95 % effective

    • B.

      The combination is 91 % tolerable

    • C.

      The combination is 97% effective

    • D.

      The combination is 97 % tolerable

    Correct Answer
    C. The combination is 97% effective
    Explanation
    The PMS study on Zimnic O reveals that the combination is 97% effective. This means that the medication has a high success rate in achieving its intended purpose or desired outcome. It suggests that the combination of ingredients in Zimnic O is highly effective in treating the condition it is prescribed for.

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  • 7. 

    Zimnic O prevents relapse because

    • A.

      Combination achieves low MIC against S.Typhi

    • B.

      It achieves high concentration in liver and gall bladder

    • C.

      Highly effective when compared to monotherapy

    • D.

      All the above

    Correct Answer
    B. It achieves high concentration in liver and gall bladder
    Explanation
    The correct answer is "It achieves high concentration in liver and gall bladder". This is because Zimnic O is effective in preventing relapse due to its ability to reach high concentrations in the liver and gall bladder. This is important because S.Typhi, the bacterium that causes typhoid fever, can persist in these organs and lead to relapse if not effectively targeted. Achieving high concentrations in these specific organs allows Zimnic O to effectively eliminate the bacteria and prevent relapse.

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  • 8. 

    The MIC of Balofloxacin against the UTI pathogen E.Coli is

    Correct Answer
    0.2 mcg /ml
    Explanation
    The MIC (Minimum Inhibitory Concentration) of Balofloxacin against the UTI (Urinary Tract Infection) pathogen E. Coli is 0.2 mcg/ml. This means that a concentration of 0.2 mcg of Balofloxacin per milliliter of the test solution is sufficient to inhibit the growth of E. Coli. A lower MIC value indicates a higher potency of the antibiotic against the specific pathogen. In this case, Balofloxacin shows strong inhibitory activity against E. Coli at a relatively low concentration.

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  • 9. 

    Does the pathogen k.pneumoniae cause UTI ?

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    The pathogen K.pneumoniae does cause UTI (urinary tract infection). UTIs are commonly caused by bacteria entering the urethra and traveling up to the bladder. K.pneumoniae is one of the bacteria that can cause UTIs, along with other common pathogens such as E.coli. Therefore, the statement "True" is correct as K.pneumoniae is indeed a pathogen that causes UTI.

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  • 10. 

    The dosage of Balofloxacin in UTI is

    • A.

      1 tab (100 mg )BID for 5 days

    • B.

      1 tab (200 mg )BID for 5 days

    • C.

      1 tab (200 mg) OD for 5 days

    • D.

      1 tab (100 mg )OD for 5 days

    Correct Answer
    A. 1 tab (100 mg )BID for 5 days
    Explanation
    The correct dosage of Balofloxacin in UTI is 1 tablet of 100 mg taken twice daily (BID) for 5 days. This means that the patient should take one tablet in the morning and one tablet in the evening, every day, for a total of 5 days. This dosage regimen ensures that enough of the medication is in the body to effectively treat the urinary tract infection and eliminate the bacteria causing it.

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