1.
All these are examples of urinary tract infections EXCEPT...
Correct Answer
E. Periurethritis
Explanation
Periurethritis is not an example of a urinary tract infection. Cystitis, urethritis, pyelonephritis, and perinephric abscess are all types of urinary tract infections. Periurethritis refers to inflammation of the tissues surrounding the urethra, rather than an infection within the urinary tract itself.
2.
UTIs are divided epidemiologically by where the infection is acquired.
Which of these are NOT examples of causative organisms of UTIs from the community?
Correct Answer
D. Serratia marcescens
Explanation
Serratia marcescens is often nosocomial and drug-resitant.
3.
All of these infectious/ virulence/ bacterial factors can lead to UTIs except...
Correct Answer
D. Tamm-Horsfall protein
Explanation
Tamm-Horsfall protein is an antiadherence factor and prevents binding of pathogens to uroepithelial cells.
4.
Which of these symptoms does not increase the probability of UTI?
Correct Answer
C. Vaginal discharge
Explanation
Vaginal discharge does not increase the probability of UTI because it is not directly related to the urinary tract. UTIs are caused by bacteria entering the urethra and multiplying in the bladder, causing symptoms such as dysuria, haematuria, suprapubic pain, and back pain. Vaginal discharge is more commonly associated with vaginal infections or other gynecological issues, rather than UTIs.
5.
Which of these are not diagnostic testing for UTI?
Correct Answer
A. C-Reactive Protein test
Explanation
The C-Reactive Protein (CRP) test is not a diagnostic testing for UTI. CRP is a protein produced by the liver in response to inflammation in the body. While a UTI can cause inflammation, the CRP test is not specific to UTIs and can be elevated in various other conditions such as infections, autoimmune diseases, and even after surgery. Therefore, it is not a reliable test for diagnosing UTIs. Urinalysis, on the other hand, is a commonly used diagnostic test for UTIs as it can detect the presence of bacteria, white blood cells, and other markers of infection in the urine. The Leucocyte esterase test is also a part of urinalysis and helps to identify the presence of white blood cells in the urine, indicating an infection. The Greiss test is not a common diagnostic test for UTIs and is used to measure nitrite levels in the urine, which can be an indicator of bacterial infection.
6.
UTIs are classified as recurrent when ________________________.
Correct Answer
E. The patient has more than three positive MSU test and urine culture per year.
Explanation
need to be confirmed by MSU
7.
Investigations in adult patients with UTI must be done for a patient who is ___________________.
Correct Answer
C. The man who has manageable type-II diabetes.
Explanation
simple rule is to investigate all men with UTI
8.
Antibiotics are used to treat UTIs. What is the mechanism of action for antibiotic cephalosporins?
Correct Answer
A. Block cell wall synthesis
Explanation
A beta-lactam drug that inhibits cell wall synthesis by inhibition of peptidoglycan cross-linking. Other drugs include- penicillin, ampicillin.
9.
Which of these drugs block protein synthesis at the 30S ribosomal subunit?
Correct Answer
C. Tetracyclines
Explanation
Tetracyclines are a group of antibiotics that inhibit protein synthesis by binding to the 30S ribosomal subunit. This prevents the attachment of aminoacyl-tRNA to the ribosome, thereby blocking the elongation of the growing peptide chain. Tetracyclines are broad-spectrum antibiotics and are effective against a wide range of bacteria.
10.
Which is the correct clinical use of aminoglycosides?
Correct Answer
B. Severe gram-negative rod infections.
Explanation
Clindamycin- Treat anaerobic infections Imipenem/ cilastatin- Drug choice for enterobacter (not important to know yet) Aminoglycosides- require oxygen uptake; therefore ineffective for anaerobes, examples- gentamicin
11.
Which of these is not responsible for the management of recurrent UTIs?
Correct Answer
C. Using contraceptive barrier methods during sex
Explanation
proanthocyanidin appears in cranberry juice (reduce attachment of pathogens to uroepithelium) The following are barrier methods of contraception. * Condom (with spermicides) * Female condom * Cervical cap (including Lea's Shield) * Diaphragm
12.
What are the typical symptoms of UTIs in children?
Correct Answer
C. Enuresis
Explanation
Enuresis, or bedwetting, is a common symptom of urinary tract infections (UTIs) in children. UTIs can cause irritation and inflammation in the bladder, leading to increased urgency and frequency of urination. In some cases, children may not be able to control their bladder and experience involuntary bedwetting. Therefore, enuresis is a typical symptom of UTIs in children.