Quiz Review Biologi Molekuler 2009/2010 (I)

40 Questions | Total Attempts: 91

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Quiz Review Biologi Molekuler 2009/2010 (I)

Quiz Review Biologi Molekuler 2009/2010 (() Program Studi Biologi (S1) Fakultas Biologi UNSOED ini mencakup materi pendahuluan sampai dengan transkripsi.Pada hari Rabu, 28 April 2010, Jam 10.00 - 22.00 WIB, Quiz ini dapat diakses tanpa password.


Questions and Answers
  • 1. 
    The nucleic acids DNA and RNA are polymers of ___________
    • A. 

      Amino acids

    • B. 

      Nucleotides

    • C. 

      Nucleic acids

    • D. 

      Glucose

    • E. 

      Nucleosides

  • 2. 
    Polysaccharides are polymers of simple sugars covalently linked by ___________
    • A. 

      Peptide bonds

    • B. 

      Hydrogen bonds

    • C. 

      Glycosidic bonds

    • D. 

      Phosphodiester bond

  • 3. 
    In nucleic acids, the bond between the bases and the sugars is _________
    • A. 

      Peptide bonds

    • B. 

      Glycosylic (or glycosidic) bond

    • C. 

      Phosphodiester bond

    • D. 

      Hydrogen bonds

  • 4. 
    In a DNA or RNA molecule, deoxyribonucleotides or ribonucleotides respectively are joined into a polymer by the covalent linkage of a phosphate group between the 5-hydroxyl of one ribose and the 3-hydroxyl of the next.This kind of bond or linkage is called ____________
    • A. 

      Peptide bonds

    • B. 

      Glycosylic (or glycosidic) bond

    • C. 

      Phosphodiester bond

    • D. 

      Hydrogen bonds

  • 5. 
    There  is a convention to write the sequences of DNA or RNA with the 5-end at the right.
    • A. 

      TRUE

    • B. 

      FALSE

  • 6. 
    In strong acid and at elevated temperatures, for example perchloric acid (HClO4) at more than 100°C, nucleic acids are hydrolyzed completely to their constituent
    • A. 

      TRUE

    • B. 

      FALSE

  • 7. 
    Chemical agents can cause the denaturation of DNA or neutral pH.
    • A. 

      Urea and ehidium bromide

    • B. 

      Urea and formamide

    • C. 

      Formamide and perchloric acid

    • D. 

      Ehidium bromide and perchloric acid

    • E. 

      Ehidium bromide and cesium chloride

  • 8. 
    The absorbance at 260 nm is used to determine the __________ of nucleic acids.
    • A. 

      Concentration

    • B. 

      Purity

    • C. 

      Double-stranded DNA

    • D. 

      Single-stranded DNA

  • 9. 
    The approximate purity of dsDNA preparations may be estimated by determination of the ratio of absorbance at 260 and 280 nm (A260/A280).
    • A. 

      TRUE

    • B. 

      FALSE

  • 10. 
    The pure dsDNA has an A260/A280 of ____
    • A. 

      2.0

    • B. 

      0.18

    • C. 

      1.8

    • D. 

      18

  • 11. 
    The pure RNA has an A260/A280 of ______
    • A. 

      2.0

    • B. 

      0.18

    • C. 

      1.8

    • D. 

      18

  • 12. 
    The DNA in E. coli cells consists of a single closed-circular DNA molecule of length 4.6 million base pairs. The DNA is packaged into a region of the cell known as _________
    • A. 

      The nucleoid

    • B. 

      The nucleus

    • C. 

      The nucleolus

    • D. 

      Tjhe nicleosome

    • E. 

      The nucleoplasm

  • 13. 
    The major protein components of chromatin are the histones; small, basic (positively charged) proteins which bind tightly to DNA. There are four families of core histone:______________
    • A. 

      H2A, H2B, H3, H4

    • B. 

      H2A, H2B, H3, H1

    • C. 

      H2A, H2B, H1, H4

    • D. 

      H1, H2B, H3, H4

  • 14. 
    Chromatin is organized into a larger structure, known as the ____________
    • A. 

      Nucleosome

    • B. 

      Chromatosome

    • C. 

      Solenoid

    • D. 

      Histone

  • 15. 
    A nucleosome core plus H1 is known as a _________________
    • A. 

      Chromatosome

    • B. 

      Chromatin

    • C. 

      Chromosome

    • D. 

      Loops

    • E. 

      Solenoid

  • 16. 
    Chromosomes greatly alter their level of compactness as cells progress through the cell cycle, varying between highly condensed chromosomes at _________ and very much more diffuse structures in _______
    • A. 

      Anaphase, interphase

    • B. 

      Metaphase, prophase

    • C. 

      Prophase, interphase

    • D. 

      Metaphase, interphase

  • 17. 
    The __________ is the constricted region where the two sister chromatids are joined in the metaphase chromosome.
    • A. 

      Centromere

    • B. 

      Telomere

    • C. 

      Kinetochore

    • D. 

      Microtubules

    • E. 

      Heterochromatin

  • 18. 
    Specialized DNA sequences that form the ends of the linear DNA molecules of the eukaryotic chromosomes
    • A. 

      Kinetochore

    • B. 

      Microtubules

    • C. 

      Centromere

    • D. 

      Telomeres

  • 19. 
    This enzyme has been used to map the regions of transcriptionally active chromatin in cells.
    • A. 

      The nuclease deoxyribonuclease I (DNase I)

    • B. 

      DNA polymerase III

    • C. 

      DNA polymerase I

    • D. 

      DNA helicase

    • E. 

      DNA primase

  • 20. 
    Enzymes which use the energy of ATP hydrolysis to move into and melt double-stranded DNA (or RNA).
    • A. 

      DNA primase

    • B. 

      DNA polymerase III

    • C. 

      DNA helicase

    • D. 

      DNA polymerase I

    • E. 

      DNA ligase

  • 21. 
    The single-stranded bubble created by DNA helicase is coated with _______________ to protect it from breakage and to prevent the DNA renaturing.
    • A. 

      DNA helicase

    • B. 

      RNA primer

    • C. 

      DNA polymerase I

    • D. 

      DNA ligase

    • E. 

      Singlestranded binding protein (Ssb)_

  • 22. 
    The enzyme ____________ attaches to the DNA and synthesizes a short RNA primer to initiate synthesis of the leading strand of the first replication fork.
    • A. 

      DNA polymerase I

    • B. 

      DNA primase

    • C. 

      DNA ligase

    • D. 

      DNA polymerase III

    • E. 

      Singlestranded binding protein (Ssb)_

  • 23. 
    Inhibitors of , such as novobiocin and oxolinic acid, are effective inhibitors of bacterial replication and have antibiotic activity.
    • A. 

      TRUE

    • B. 

      FALSE

  • 24. 
    DNA primase synthesizes RNA primers every 1000–2000 nt on the lagging strand.
    • A. 

      TRUE

    • B. 

      FALSE

  • 25. 
    Both leading and lagging strand primers are elongated by ______
    • A. 

      DNA polymerase III

    • B. 

      DNA primase

    • C. 

      DNA gyrase

    • D. 

      DNA polymerase I

    • E. 

      DNA ligase

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