Antihistamines Pharmacology Exam Quiz

20 Questions | By Perduekm | Updated: Dec 6, 2022 | Attempts: 9779

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Antihistamines Pharmacology Exam Quiz - Quiz

How about an antihistamines pharmacology exam quiz? When you catch a cold, some symptoms accompany it, and the use of antihistamines gives you a way of relieving them. Below is the fourth practice exam designed to help you review what you understood about these types of drugs. Why don’t you give it a try and see what you know about them so far? Wish you all the best of luck with this quiz.

Questions and Answers

1.

A 43 yo ship captain complains of seasonal allergies. Which one of the following would be indicated?
- A.
  
  Cyclizine
- B.
  
  Doxepin
- C.
  
  Doxylamine
- D.
  
  Fexofenadine
2.

Which one of the following states regarding H1 antihistamines is correct?
- A.
  
  Second-generation H1 antihistamines are relatively free of adverse effects.
- B.
  
  The motor coordination involved in driving an automobile is not affected by the use of first gen H1 antihistamines.
- C.
  
  H1 antihistamines can be used in the treatment of acute anaphylaxis.
- D.
  
  Both first and second-gen H1 antihistamines readily penetrate the blood-brain barrier.
3.

Which one of the following agents could significantly impair the ability to drive an automobile?
- A.
  
  Ergotamine
- B.
  
  Fexofenadine
- C.
  
  Diphenhydramine
- D.
  
  Ranitidine
4.

Which of the following is the most frequent side effect of H1 antihistamines that is less common with second-gen antihistamines?
- A.
  
  Decreased appetite
- B.
  
  Sedation
- C.
  
  Bradycardia
- D.
  
  Hypertension
5.

Prostaglandins, histamine, and serotonin all belong to a group of endogenous compounds called
- A.
  
  Bellacoids
- B.
  
  Autacoids
- C.
  
  Donnacoids
- D.
  
  Don't know
6.

Which type of cell is histamine mostly produced in?
- A.
  
  Eosinophil
- B.
  
  Basophil
- C.
  
  Mast cell
- D.
  
  Cytokines
7.

Histamine is distributed equally among the tissue.
- A.
  
  True
- B.
  
  False
8.

Histamine has no clinical indication.
- A.
  
  True
- B.
  
  False
9.

Histamine is released in response to various stimuli and effects of binding to one of four types of receptors. Which group of receptors are widely expressed and targeted by clinically useful drugs?
- A.
  
  H1 and H4
- B.
  
  H1 and H2
- C.
  
  H2 and H4
- D.
  
  H3 and H1
10.

Histamine stimulates what type of cell in the stomach?
- A.
  
  Alveolar cells
- B.
  
  Interstitial cells
- C.
  
  Gastric acid
- D.
  
  Parietal cell
11.

H1 receptor blockers are more effective in reversing symptoms than preventing them.
- A.
  
  True
- B.
  
  False
12.

The drug of choice in systemic anaphylactic shock is H1 receptor blockers.
- A.
  
  True
- B.
  
  False
13.

H1 antihistamines used for motion sickness and nausea include:
- A.
  
  Diphenhydramine and meclizine
- B.
  
  Toradol and meclizine
- C.
  
  Epinephrine and loratadine
- D.
  
  Loratadine
14.

What is one of the benefits of the pK of many oral antihistamines?
- A.
  
  Allows for twice-daily dosing
- B.
  
  Allows for once-daily dosing
- C.
  
  Allows for sub injections
- D.
  
  None of these
15.

Some H1 receptor blockers have effects on other tissue. One of the effects of these drugs on serotonin receptors is?
- A.
  
  Decreased appetite
- B.
  
  Increased appetite
- C.
  
  Urinary retention
- D.
  
  Polydipsia
16.

Again on the extra effects of H1 receptor blockers...which of these is NOT an effect on H1 receptor blockers at cholinergic receptors?
- A.
  
  Increased hypotension
- B.
  
  Increased dry mouth
- C.
  
  Increased urinary retention
- D.
  
  Sinus tachycardia
17.

Contraindication of antihistamines with patients taking MAOIs - what is the effect?
- A.
  
  Exacerbation of anticholinergic effects
- B.
  
  Decreased anticholinergic effects
- C.
  
  Exacerbation of antimuscarinic effects
- D.
  
  Decreased antimuscarinic effects
18.

You should not use nasal decongestants longer than how many days?
- A.
  
  1
- B.
  
  5
- C.
  
  7
- D.
  
  3
19.

WHAT IS THE term for rebound nasal congestion?
- A.
  
  Rhinitis medusa
- B.
  
  Polly pockets
- C.
  
  Rhinitis medicamentosa
- D.
  
  Rhinitis adversica
20.

H1 and H2 receptor blockers can cause a classic "triple response" on the skin. Does this include which of the following?
- A.
  
  Pain, pallor, pink
- B.
  
  Wheal, reddening, and flare
- C.
  
  Purpura, edema, and pain
- D.
  
  Wheal, pallor, and flare