Pharmacology Exam 4 Antihistamines
Settings
-
+
When you catch cold, there are some symptoms that accompany it and the use of antihistamines gives you a way of relieving them. Below is the fourth practice exam that is designed to help you review what you understood about these types of drugs. Why don’t you give it a try and see what you know about them so far?
- 1.A 43 yo ship captain complains of seasonal allergies. Which one of the following would be indicated?
- A.
Cyclizine
- B.
Doxepin
- C.
Doxylamine
- D.
Fexofenadine
- 2.
- A.
Second generation H1 antihistamines are relatively free of adverse effects
- B.
The motor coordination involved in driving an automobile is not affected by the use of first gen H1 antihistamines.
- C.
H1 antihistamines can be used in the treatment of acute anaphylaxis.
- D.
Both first and second gen H1 antihistamines readily penetrate the blood brain barrier
- 3.Which one of the following agents could significantly impair the ability to drive an automobile?
- A.
Ergotamine
- B.
Fexofenadine
- C.
Diphenhydramine
- D.
Ranitidine
- 4.Which of the following is the most frequent side effect of H1 antihistamines that is less common with second gen antihistamines?
- A.
Decreased appetite
- B.
Sedation
- C.
Bradycardia
- D.
Hypertension
- 5.Prostaglandins, histamine and serotonin all belong to a group of endogenous compounds called
- A.
Bellacoids
- B.
Autacoids
- C.
Donnacoids
- D.
Don't know
- 6.Which type of cell is histamine mostly produced in?
- A.
Eosinophil
- B.
Basophil
- C.
Mast cell
- D.
Cytokines
- 7.Histamine is distributed equally among tissue.
- A.
True
- B.
False
- 8.Histamine has no clinical indication.
- A.
True
- B.
False
- 9.
- A.
H1 and H4
- B.
H1 and H2
- C.
H2 and H4
- D.
H3 and H1
- 10.
- A.
Smooth muscle relaxation and increase in capillary permeability
- B.
Smooth muscle contraction and increase in capillary permeability
- 11.Histamine stimulates what type of cell in the stomach?
- A.
Alveolar cells
- B.
Interstitial cells
- C.
Gastric acid
- D.
Parietal cell
- 12.H1 receptor blockers are more effective in reversing symptoms than preventing them.
- A.
True
- B.
False
- 13.
- A.
True
- B.
False
- 14.H1 antihistamines used for motion sickness and nausea include
- A.
Diphenhydramine and meclizine
- B.
Toradol and meclizine
- C.
Epinephrine and loratidine
- D.
Loratidine
- 15.H1 antihistamines are contraindicated in which patient population?
- A.
Those who need to be awake (now who doesn't?)
- B.
Those with easy jobs
- 16.What is one of the benefits of the pK of many oral antihistamines?
- A.
Allows for twice daily dosing
- B.
Allows for once daily dosing
- C.
Allows for subq injections
- D.
Allow to divided into many smaller doses
- 17.Which class doesn't cross the BBB?
- A.
H1
- B.
H2
- 18.Some H1 receptor blockers have effects on other tissue. One of the effects of these drugs on serotonin receptors is?
- A.
Decreased appetite
- B.
Increased appetite
- C.
Urinary retention
- D.
Polydipsia
- 19.Again on the extra effects of H1 receptor blockers...which of these is NOT an effect on H1 receptor blockers at cholinergic receptors?
- A.
Increased hypotension
- B.
Increased dry mouth
- C.
Increased urinary retention
- D.
Sinus tachycardia
- 20.What effect would antihistamines potentially have on someone taking a CNS depressant?
- A.
Decreased effects of CNS depressant
- B.
No affect on CNS depressant
- C.
Increased effects of CNS depressant
- 21.Contraindication of antihistamines with patients taking MAOIs - what is the effect?
- A.
Exacerbation of anticholinergic effects
- B.
Decreased anticholinergic effects
- C.
Exacerbation of antimuscarinic effects
- D.
Decreased antimuscarinic effects
- 22.Nasal decongestants are
- A.
Beta adrenergic agonists
- B.
Alpha adrenergic agonists
- C.
Beta adrenergic antagonists
- D.
Alpha adrenergic antagonists
- 23.Effect of nasal decongestants......
- A.
Constrict dilated arterioles in nasal mucosa and reduce airway resistance
- B.
Dilate constricted arterioles in nasal mucosa and reduce airway resistance
- 24.You should not use nasal decongestants longer than how many days?
- A.
1
- B.
5
- C.
7
- D.
3
- 25.WHAT IS THE term for rebound nasal congestion?
- A.
Rhinitis medusa
- B.
Polly pockets
- C.
Rhinitis medicamentosa
- D.
Rhinitis adversica
- 26.H1 and H2 receptor blockers can cause a classic "triple response" on skin. This includes which the following?
- A.
Pain, pallor, pink
- B.
Wheal, reddening and flare
- C.
Purpura, edema and pain
- D.
Wheal, pallor and flare
Back to top
