Tear Film
.
- 1.
Reflex tears are not part of the tear film
- A.
True
- B.
False
Correct Answer
A. True -
- 2.
Anteriorly to posteriorly, in what order are the layers of the tear film arranged?
- A.
Mucin, aqueous, lipid
- B.
Lipid, aqueous, mucin
- C.
Lipid, mucin, aqueous
- D.
Mucin, lipid, aqueous
- E.
Aqueous, mucin, lipid
Correct Answer
B. Lipid, aqueous, mucin -
- 3.
What is the thickest layer of the tear film?
- A.
Aqueous
- B.
Mucin
- C.
Lipid
Correct Answer
A. Aqueous -
- 4.
What layer of the tear film is in contact with glycocalyx?
- A.
Aqueous
- B.
Mucin
- C.
Lipid
Correct Answer
B. Mucin -
- 5.
Which of the following is true of glycocalyx? (Select 3)
- A.
Protects against bacterial pathogens
- B.
Disruption of it can lead to dry eye
- C.
Surface atea can be increased with microvilli
- D.
Contact lenses protect this layer of proteins
- E.
Interacts with lipid layer of tear film
Correct Answer(s)
A. Protects against bacterial pathogens
B. Disruption of it can lead to dry eye
C. Surface atea can be increased with microvilli -
- 6.
How does mucin interact with glycocalyx
- A.
The sugar side chains from both surfaces crosslink
- B.
Hydrogen bonding of the protein backbones
- C.
Covalent bonding of the side chains
- D.
The sugar side chain of the glycocalyx cross links with the protein backbone of mucin
Correct Answer
A. The sugar side chains from both surfaces crosslink -
- 7.
Mucin is a homogenous collection of low molecular weight glycoproteins
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
mucin is a heterogenous collection of high molecular weight glycoproteinsRate this question:
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- 8.
Which of the following is true of mucin? (select 3)
- A.
Provide hydrophilic surface
- B.
Provide hydrophobic surface
- C.
Decreases surface tension
- D.
Interact with trefoil factor family peptides
- E.
Increases wetting angle of cornea
Correct Answer(s)
A. Provide hydrophilic surface
C. Decreases surface tension
D. Interact with trefoil factor family peptides -
- 9.
A surfactant does which of the following
- A.
Decrease surface tension reducing dry areas
- B.
Decrease surface tension increasing dry areas
- C.
Increase surface tension reducing dry areas
- D.
Increase surface tension increasing dry areas
Correct Answer
A. Decrease surface tension reducing dry areas -
- 10.
A highly wettable material will have spread water across the tear film and have a low contact angle
- A.
True
- B.
False
Correct Answer
A. True -
- 11.
A high wetting angle means that the surface does not wet well and has many dry areas
- A.
True
- B.
False
Correct Answer
A. True -
- 12.
Which phase of the mucin layer do goblet cells form?
- A.
Gel
- B.
Aqueous
- C.
Fat
- D.
Cellular
Correct Answer
A. Gel -
- 13.
In what way do goblet cells secret mucus?
- A.
Via vesicles by calcium dependent exocytosis
- B.
Passive export
- C.
Sodium potassium ATPase
- D.
None of the above
Correct Answer
A. Via vesicles by calcium dependent exocytosis -
- 14.
How can the secretion of mucin be blocked in regards to neural control?
- A.
Muscarinic agonist
- B.
Muscarinic antagonist
- C.
Cholinergic agonist
- D.
Cholinergic antagonist
Correct Answer
B. Muscarinic antagonist -
- 15.
What is the role of P2Y2 receptor agonists in mucin release? (Select 3)
- A.
Mediates mucousal surface lubrication
- B.
Stimulate the release of mucous and other tear components
- C.
Stimulation also increases Cl- secretion by corneal epithelium
- D.
Inhibit the release of mucous and other tear components
- E.
Stimulation also decreases Cl- secretion by corneal epithelium
Correct Answer(s)
A. Mediates mucousal surface lubrication
B. Stimulate the release of mucous and other tear components
C. Stimulation also increases Cl- secretion by corneal epithelium -
- 16.
Which of the following are mucin secretory glands? (Select 3)
- A.
Goblet cells
- B.
Crypts of Henle
- C.
Manz
- D.
Krausse
- E.
Wolfring
Correct Answer(s)
A. Goblet cells
B. Crypts of Henle
C. Manz -
- 17.
What bacteria produces cholestryl esterase and fatty wax esterase and can lead to meibomian dysfunction (meibomitis) and can be treated with doxycycline?
- A.
Staphilococcous aureus
- B.
Streptococcus pneumonae
- C.
Herpes zoster
- D.
Pseudomonas aeuruginosa
Correct Answer
A. Staphilococcous aureus -
- 18.
What electrolyte is greatest in amount in the serum
- A.
K+
- B.
Cl-
- C.
Na+
- D.
Ca2+
Correct Answer
A. K+ -
- 19.
Ions enter the lumen via
- A.
Ligand-gated channels
- B.
Na+/K+ ATPase
- C.
Calcium dependent exocytosis
- D.
Passive diffusion
Correct Answer
A. Ligand-gated channels -
- 20.
Protein secretory vesicles are stored and released upon stimulation via [Blank} mediated pathways involving enzymes
Correct Answer
G proteinExplanation
or cAMPRate this question:
- 21.
60% (most) of total proteins present in the aqueous are
- A.
Albumin
- B.
Alpha and beta globulin
- C.
Gamma globulin (like IgA)
- D.
Amino acids
Correct Answer
A. Albumin -
- 22.
Which of the following is true of lactoferrin? (select 3)
- A.
Tear specific pre-albumin
- B.
Bacteriostatic and may be bacteriolytic
- C.
Binds Fe+ ions essential to bacterial metabolism
- D.
A type of immunoglobulin
- E.
Hydrolyzes beta 1-4 glycosidic bond
- F.
Only bateriolytic
Correct Answer(s)
A. Tear specific pre-albumin
B. Bacteriostatic and may be bacteriolytic
C. Binds Fe+ ions essential to bacterial metabolism -
- 23.
________ is a condition where PLA2 is secreted by inflammatory cells which induces the release of histamines, prostaglandins, and erotomim causing tear film disruption.
Correct Answer(s)
blepharitis - 24.
________ is defined as dry mouth resulting from reduced or absent saliva flow and is associated with Sjogrens syndrome
Correct Answer(s)
xerostomia - 25.
Non sjorgrens syndrome is local autoimmunity/inflammatory based
- A.
True
- B.
False
Correct Answer
A. True -
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Sep 20, 2017Quiz Edited by
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Sep 17, 2017Quiz Created by
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