Question Paper - Preliminary Screening - Quiz, Flashcards & Trivia

1. Select the change of Km and Vmax value in Lineweaver-Burk double reciprocal plot under the presence of different inhibitors:

Competitive inhibition

Non-competitive inhibition

Uncompetitive inhibition

Submit

2. Match broad enzyme class to appropriate business segments :

Cellulases / Hemicellulases

Microbial Inoculants

Hydrolases

Protease / amylase

Submit

3. Novozymes acquired enzyme business of which Indian company?

Advance Enzyme

Biocon

Praj Industries

DuPont

Novozymes acquired the enzyme business of Biocon, an Indian company.

Explanation

Novozymes acquired the enzyme business of Biocon, an Indian company.

4. Which of the following inventions are patentable?

Naturally occurring microbes

Non-naturally occurring microbes

GMO organisms

Synthetic Cells

2, 3 & 4

All of the above

The correct answer is 2, 3 & 4 because naturally occurring microbes cannot be patented as they are not inventions. However, non-naturally occurring microbes, GMO organisms, and synthetic cells can be patented as they are man-made inventions that are not naturally occurring.

Explanation

The correct answer is 2, 3 & 4 because naturally occurring microbes cannot be patented as they are not inventions. However, non-naturally occurring microbes, GMO organisms, and synthetic cells can be patented as they are man-made inventions that are not naturally occurring.

5. Is "Solar cooker" a patentable invention?

Yes

No

Yes but only with additional novel elements

No because it’s based on natural phenomena

The correct answer is "Yes but only with additional novel elements." This means that a solar cooker can be considered a patentable invention, but only if it includes additional unique and innovative elements. Simply using solar energy to cook food may not be enough to qualify for a patent, but if the solar cooker incorporates new and inventive features, it may be eligible for patent protection.

Explanation

The correct answer is "Yes but only with additional novel elements." This means that a solar cooker can be considered a patentable invention, but only if it includes additional unique and innovative elements. Simply using solar energy to cook food may not be enough to qualify for a patent, but if the solar cooker incorporates new and inventive features, it may be eligible for patent protection.

6. CRISPR is "Clustered regularly interspaced short palindromic repeats" discovered in prokaryotes:(A) CRISPR related to bacterial defense / immune system(B) CRISPR can use in gene therapies, enzyme modification, bio-agricuture applicationsSelect the appropriate response:

A – Correct, B – Partially correct

A & B – Both are correct

A & B - Partially Correct

A – Correct, B – wrong

CRISPR, which stands for "Clustered regularly interspaced short palindromic repeats," was discovered in prokaryotes. It is correct to say that CRISPR is related to the bacterial defense/immune system, as it plays a crucial role in protecting bacteria from viral infections. Additionally, it is also correct to say that CRISPR can be used in gene therapies, enzyme modification, and bio-agriculture applications, as it has revolutionized the field of genetic engineering and has immense potential in various applications. Therefore, both options A and B are correct.

Explanation

CRISPR, which stands for "Clustered regularly interspaced short palindromic repeats," was discovered in prokaryotes. It is correct to say that CRISPR is related to the bacterial defense/immune system, as it plays a crucial role in protecting bacteria from viral infections. Additionally, it is also correct to say that CRISPR can be used in gene therapies, enzyme modification, and bio-agriculture applications, as it has revolutionized the field of genetic engineering and has immense potential in various applications. Therefore, both options A and B are correct.

7. The Molecular Weight of bacteriophage DNA is 1.5 X 10⁸ (double stranded). How many amino acids can be coded by phage DNA? (average weight of DNA basepair is 618)

8k codons

80k codons

800k codons

800 codons

The molecular weight of the bacteriophage DNA is given as 1.5 X 10^8. The average weight of a DNA base pair is given as 618. To calculate the number of amino acids that can be coded by the phage DNA, we need to divide the molecular weight of the DNA by the weight of a single base pair. This gives us 1.5 X 10^8 / 618 = 242573. Since each codon codes for a single amino acid, the number of codons that can be coded by the phage DNA is equal to the number of amino acids, which is approximately 242573. Therefore, the correct answer is 80k codons, as 80k is the closest option to 242573.

Explanation

The molecular weight of the bacteriophage DNA is given as 1.5 X 10^8. The average weight of a DNA base pair is given as 618. To calculate the number of amino acids that can be coded by the phage DNA, we need to divide the molecular weight of the DNA by the weight of a single base pair. This gives us 1.5 X 10^8 / 618 = 242573. Since each codon codes for a single amino acid, the number of codons that can be coded by the phage DNA is equal to the number of amino acids, which is approximately 242573. Therefore, the correct answer is 80k codons, as 80k is the closest option to 242573.

8. What is the pH of 10^-8N HCL solution?

8

Between 8 and 9

Between 7 and 8

Between 6 and 7

The pH of a solution is a measure of its acidity or alkalinity. A pH value between 6 and 7 indicates that the solution is slightly acidic. Since HCl is a strong acid, it completely dissociates in water to form H+ ions. Therefore, a 10-8 N HCl solution will have a high concentration of H+ ions, resulting in a slightly acidic pH value between 6 and 7.

Explanation

The pH of a solution is a measure of its acidity or alkalinity. A pH value between 6 and 7 indicates that the solution is slightly acidic. Since HCl is a strong acid, it completely dissociates in water to form H+ ions. Therefore, a 10-8 N HCl solution will have a high concentration of H+ ions, resulting in a slightly acidic pH value between 6 and 7.

9. Which of the above stated technology statement discloses application of exogenous RNA / dsRNA for bio-agriculture application ?

A, B & C

A & C

Only A

None of the above

The correct answer is A & C because both statements A and C mention the application of exogenous RNA / dsRNA in bio-agriculture.

Explanation

The correct answer is A & C because both statements A and C mention the application of exogenous RNA / dsRNA in bio-agriculture.

10. Probability of co-occurrence of AABB or AAbb genes in the progeny population:

.53

.56

.27

.18

The probability of co-occurrence of AABB or AAbb genes in the progeny population is .56. This means that there is a 56% chance that either AABB or AAbb genes will be present in the offspring.

Explanation

The probability of co-occurrence of AABB or AAbb genes in the progeny population is .56. This means that there is a 56% chance that either AABB or AAbb genes will be present in the offspring.

11. Focus of the above stated invention is:

Novel compositions

Novel bacterial strains

Novel composition containing bacterial strains

All of the above

The focus of the above-stated invention is a novel composition containing bacterial strains. This means that the invention involves a new combination or formulation of bacterial strains that has not been previously used or discovered. The invention may have identified specific bacterial strains that have unique properties or characteristics, and the composition containing these strains could have potential applications in various fields such as medicine, agriculture, or environmental science.

Explanation

The focus of the above-stated invention is a novel composition containing bacterial strains. This means that the invention involves a new combination or formulation of bacterial strains that has not been previously used or discovered. The invention may have identified specific bacterial strains that have unique properties or characteristics, and the composition containing these strains could have potential applications in various fields such as medicine, agriculture, or environmental science.

12. Which is / are the merger & acquisitions happened in the biotechnology industry:

DuPont & Dow Chemical

Syngenta & ChemChina

Bayer & Monsanto

1 & 3

All of the above

The correct answer is "All of the above" because all three mergers and acquisitions listed (DuPont & Dow Chemical, Syngenta & ChemChina, and Bayer & Monsanto) have occurred in the biotechnology industry.

Explanation

The correct answer is "All of the above" because all three mergers and acquisitions listed (DuPont & Dow Chemical, Syngenta & ChemChina, and Bayer & Monsanto) have occurred in the biotechnology industry.

13. How many different linear tetrapeptides can be made from four different neutral amino acids (a) using any of the four amino acids for any position (repletion allowed) (b) using amino acid only once in a chain?

24 & 64

256 & 24

64 & 24

64 & 64

not-available-via-ai

Explanation

not-available-via-ai

14. Recombinant frequency for aabb and AABB gametes:

27 m.u

5.8 m.u

3.1 m.u

22 m.u

The recombinant frequency for aabb and AABB gametes is 5.8 m.u. Recombinant frequency refers to the percentage of offspring that show a combination of traits different from those of the parents. In this case, the recombinant frequency suggests that 5.8% of the offspring will have traits that differ from both the aabb and AABB gametes. This indicates a certain level of genetic recombination occurring during the formation of gametes.

Explanation

The recombinant frequency for aabb and AABB gametes is 5.8 m.u. Recombinant frequency refers to the percentage of offspring that show a combination of traits different from those of the parents. In this case, the recombinant frequency suggests that 5.8% of the offspring will have traits that differ from both the aabb and AABB gametes. This indicates a certain level of genetic recombination occurring during the formation of gametes.

15. Probability of co-occurrence of aa and bb genes in the progeny population:

.22

.18

.03

.40

The probability of co-occurrence of aa and bb genes in the progeny population is .40. This means that there is a 40% chance that both aa and bb genes will be present in the offspring.

Explanation

The probability of co-occurrence of aa and bb genes in the progeny population is .40. This means that there is a 40% chance that both aa and bb genes will be present in the offspring.

16. Above invention could be used in the treatment of:

Cardio-vascular disorders

Obesity

Hypolipoproteinemia

1 & 2

All of the above

The above invention could be used in the treatment of cardio-vascular disorders, obesity, and hypolipoproteinemia. This means that it has potential applications in treating various conditions related to the heart, weight management, and low levels of lipoproteins in the blood.

Explanation

The above invention could be used in the treatment of cardio-vascular disorders, obesity, and hypolipoproteinemia. This means that it has potential applications in treating various conditions related to the heart, weight management, and low levels of lipoproteins in the blood.