MLT Chemistry Test
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Quiz for Chemistry. Enjoy it.
- 1.
- A.
Free amino acids
- B.
Free carboxyl groups
- C.
Peptide bonds
- D.
Tyrosine residues
- 2.Calcium concentration in the serum is regulated by?
- A.
Insulin
- B.
Parathyroid hormone
- C.
Thyroxin
- D.
Vitamin C
- 3.In the liver, bilirubin is converted to:
- A.
Urobilinogen
- B.
Urobilin
- C.
Bilirubin-albumin complex
- D.
Bilirubin diglucuronide
- 4.The osmolality of a urine or serum specimen is measured by a change in the?
- A.
Freezing point
- B.
Sediment point
- C.
Midpoint
- D.
Osmotic pressure
- 5.Which of the following steroids is an adrenal cortical hormone?
- A.
Angiotensinogen
- B.
Corticosterone
- C.
Progesterone
- D.
Pregnanetriol
- 6.Which two conditions can “physiologically” elevate serum alkaline phosphatase?
- A.
Rickets, hyperparathyroidism
- B.
Obstructive jaundice
- C.
Growth, third trimester of pregnancy
- D.
Viral hepatitis, infectious mononucleosis
- 7.
- A.
A normal finding
- B.
Cushing’s syndrome
- C.
Addison’s disease
- D.
Hypopituitarism
- 8.In electrophoretic analysis, buffers?
- A.
Stabilize electrolytes
- B.
Maintain basic PH
- C.
Act as a carrier for ions
- D.
Produce an effect on protein configuration
- 9.The T3 resin uptake test is a measure of?
- A.
Circulating T3
- B.
Bound T3
- C.
Binding capacity of thyroxine-binding globulin
- D.
Total thyroxine-binding globulin
- 10.
- A.
Direct colorimetric measurement of dissolved CO2
- B.
Calculations of blood PH and total CO2 concentration
- C.
Measurement of CO2-saturated hemoglobin
- D.
Measurement of CO2 consumed at the cathode
- 11.Which of the following serum constituents is unstable if a blood specimen is left standing at room temperature for 8 hours before processing?
- A.
Cholesterol
- B.
Triglyceride
- C.
Creatinine
- D.
Glucose
- 12.Total iron-binding capacity measures the serum iron transporting capacity of?
- A.
Hemoglobin
- B.
Ceruloplasmin
- C.
Transferrin
- D.
Ferritin
- 13.In a spectrophotometer, light of a specific wavelength can be isolated from white light with a(n)?
- A.
Double beam
- B.
Diffraction grating
- C.
Aperture
- D.
Slit
- 14.Absorbance (A) of a solution may be converted to percent transmittance (%T) using the formula?
- A.
1 + Log %T
- B.
2 + Log %T
- C.
1 - Log %T
- D.
2 - Log %T
- 15.A condition in which erythrocyte protoporphyrin is increased is?
- A.
Acute intermittent porphyria
- B.
Iron Deficiency anemia
- C.
Porphyria cutanea tarda
- D.
Acute porphyric attack
- 16.
- A.
2 Na x (Glucose/20) x (BUN/3)
- B.
Na + (2 x Glucose/20) x (BUN/3)
- C.
2 Na + Glucose/20 + (BUN/3)
- D.
2 Na + Glucose/3 + (BUN/20)
- 17.The first step to be taken when attempting to repair a piece of electronic equipment is?
- A.
Check all the electronic connections
- B.
Reset all the printed circuit boards
- C.
Turn the instrument off
- D.
Replace all the fuses
- 18.Most of the carbon dioxide present in the blood is in the form of?
- A.
Dissolve CO2
- B.
Carbonate
- C.
Bicarbonate ion
- D.
Carbonic acid
- 19.The statistical term for the average value is the?
- A.
Mode
- B.
Median
- C.
Mean
- D.
Coefficient of variation
- 20.An index of precision is statistically known as the?
- A.
Median
- B.
Mean
- C.
Standard deviation
- D.
Coefficient of variation
- 21.The most frequent value in a collection of data is statistically known as the?
- A.
Mode
- B.
Median
- C.
Mean
- D.
Standard deviation
- 22.The middle value of a data set is statistically known as the?
- A.
Mean
- B.
Median
- C.
Mode
- D.
Standard deviation
- 23.In a specimen collected for plasma glucose analysis, sodium floride?
- A.
Serves as a coenzyme of hexokinase
- B.
Prevents reactivity of non-glucose reducing substances
- C.
Precipitates proteins
- D.
Inhibits glycolysis
- 24.The serum that contributes to most serum osmolality is?
- A.
Glucose
- B.
Sodium
- C.
Chloride
- D.
Urea
- 25.Which family of steroid hormones is characterized by an unsaturated A ring?
- A.
Progestins
- B.
Estrogens
- C.
Androgens
- D.
Glucocorticoids
- 26.
- A.
Alpha-1 globulin
- B.
Alpha1- globulin and alpha-2 globulin
- C.
Alpha-2 globulin and beta globulin
- D.
Beta globulin and gamma globulin
- 27.The following lab results were obtained from arterial blood: sodium 136 mEq/L pH 7.32 Potassium 4.4 mEq/L PCO2 79 mm Hg Chloride 92 mEq/L Bicarbonate 40 mEq/L these results are compatible with?
- A.
Respiratory alkalosis
- B.
Respiratory acidosis
- C.
Metabolic alkalosis
- D.
Metabolic acidosis
- 28.Which of the following statements about fluorometry are true?
- A.
A compound is said to fluoresce when it absorbs light at one wavelength and emits light at a second wave length
- B.
Detectors in fluorometers are placed 180 degrees from the excitation source
- C.
It is less sensitive than spectrophotometry
- D.
It avoids the necessity for complexing of components because fluorescence is a native property
- 29.Two standard deviations is the acceptable limit of error in the chemistry laboratory. If you run the normal control 100 times, how many of the values wou;d be out of control due to random error?
- A.
1
- B.
5
- C.
10
- D.
20
- 30.Serum anion gap is increased in patients with?
- A.
Renal tubular acidosis
- B.
Diabetic alkalosis
- C.
Metabolic acidosis due to diarrhea
- D.
Lactic acidosis
- 31.The nanometer is used as a measure of?
- A.
Absorbance
- B.
% transmittance
- C.
Intensity of radiant energy
- D.
Wavelength of radiant energy
- 32.A common cause of respiratory alkalosis is?
- A.
Vomiting
- B.
Starvation
- C.
Asthma
- D.
Hyperventilation
- 33.Major actions of angiotensin II include?
- A.
Increased pituitary secretion of rennin
- B.
Increased vasoconstriction
- C.
Increased parathyroid hormone secretion by the parathyroid
- D.
Decreased adrenal secretion of aldosterone
- 34.The anion gap is useful for QC of laboratory results for?
- A.
Amino acids and proteins
- B.
Blood gas analyses
- C.
Sodium, potassium, chloride, and total CO2
- D.
Calcium, phosphorus, and magnesium
- 35.Which of the following electrolytes is the chief plasma cation whose main function is maintaining osmotic pressure?
- A.
Chloride
- B.
Calcium
- C.
Potassium
- D.
Sodium
- 36.What is the molarity of a solution that contains 18.7 g of KCI (MW=74.5) in 500 ml of water?
- A.
0.1
- B.
0.5
- C.
1.0
- D.
5.0
- 37.The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and?
- A.
Sodium
- B.
Potassium
- C.
Calcium
- D.
Chloride
- 38.The different water content of erythrocytes and plasma makes true glucose concentrations in whole blood a function of the?
- A.
Hematocrit
- B.
Leukocyte count
- C.
Erythrocyte count
- D.
Erythrocyte indices
- 39.Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in?
- A.
Bohr’s effect
- B.
O2 content
- C.
Bicarbonate buffer
- D.
Carbonic anhydrase
- 40.Metabolic acidosis is described as a(n)?
- A.
Increase in CO2 content and PCO2 with a decreased pH
- B.
Decrease in CO2 content with an increased pH
- C.
Increase in CO2 with and increased pH
- D.
Decrease in CO2 content and PCO2 with a decreased pH
- 41.The normal range for the pH of arterial blood measured at 37 degrees Celsius is?
- A.
7.28-7.34
- B.
7.33-7.37
- C.
7.35-7.45
- D.
7.45-7.50
- 42.Hydrogen ion concentration (pH) in blood is usually determined by means of which of the following electrodes?
- A.
Silver
- B.
Glass
- C.
Platinum
- D.
Platinum-lactate
- 43.The conversion of glucose or other hexoses into lactate or pyruvate is called?
- A.
Glycogenesis
- B.
Glycogenolysis
- C.
Gluconeogenesis
- D.
Glycolysis
- 44.A reciprocal relationship exists between?
- A.
Sodium and potassium
- B.
Calcium and phosphorus
- C.
Chloride and CO2
- D.
Calcium and magnesium
- 45.Respiratory acidosis is described as a(n)?
- A.
Increase in CO2 content and PCO2 with a decreased pH
- B.
Decrease in CO2 content with an increased pH
- C.
Increase in CO2 content with an increased pH
- D.
Decrease in CO2 content and PCO2 with a decreased pH
- 46.Which of the following hemoglobins has glucose-6-phosphate on the amino-terminal valine of the beta chain?
- A.
S
- B.
C
- C.
A2
- D.
A1c
- 47.The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport?
- A.
Cholesterol from peripheral cells to the liver
- B.
Cholesterol and Phospholipids to peripheral cells
- C.
Exogenous triglycerides
- D.
Endogenous triglycerides
- 48.A hospitalized patient is experiencing increased neuromuscular irritability (tetany). Which of the following tests should be ordered immediately?
- A.
Calcium
- B.
Phosphorus
- C.
BUN
- D.
Glucose
- 49.Sixty to seventy-five percent of the plasma cholesterol is transported by?
- A.
Chylomicrons
- B.
VLDL
- C.
LDL
- D.
HDL
- 50.Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of?
- A.
Thyroxine-binding prealbumin
- B.
Albumin
- C.
Thyroxine-binding globulin
- D.
Thyroid-stimulating hormone
- 51.Which of the following methods employs a highly specific antibody to thyroxine?
- A.
Total T4 by competitive protein binding
- B.
T4 by RIA
- C.
T4 by column
- D.
T4 by equilibrium dialysis
- 52.The extent to which measurements agree with the true value of the quantity being measured is known as?
- A.
Reliability
- B.
Accuracy
- C.
Reproducibility
- D.
Precision
- 53.When myocardial infarction occurs, the first enzyme to become elevated is?
- A.
CK
- B.
LD
- C.
AST
- D.
ALT
- 54.In the Jaffe reaction, creatinine reacts with?
- A.
Alkaline sulfasalazine solution to produce an orange-yellow complex
- B.
Potassium iodide to form a reddish-purple complex
- C.
Sodium nitroferricyanide to yield a reddish-brown color
- D.
Alkaline picrate solution to yield and orange-red complex
- 55.Which of the following represents the end product of purine metabolism in humans?
- A.
AMP and GMP
- B.
DNA and RNA
- C.
Allantoin
- D.
Uric acid
- 56.The biological most active, naturally occurring androgen is?
- A.
Androstenedione
- B.
Dehydroepiandrosterone
- C.
Epiandrosterone
- D.
Testosterone
- 57.Bile acid concentrations are useful to asses?
- A.
Diabetes mellitus
- B.
Hepatobiliary disease
- C.
Intestinal Malabsorption
- D.
Kidney function
- 58.Which of the following is secreted by the placenta and used for the early detection of pregnancy?
- A.
Follicle-stimulating hormone (FSH)
- B.
Human Chorionic gonadotropin (HCG)
- C.
Luteinizing hormone (LH)
- D.
Progesterone
- 59.Decreased serum iron associated with increased TIBC is compatible with which of the following disease states?
- A.
Anemia of chronic infection
- B.
Iron deficiency anemia
- C.
Chronic liver disease
- D.
Nephrosis
- 60.The principle excretory form of nitrogen is?
- A.
Amino acids
- B.
Creatinine
- C.
Urea
- D.
Uric acid
- 61.A 45 year old male of average height and weight was admitted to the hospital for renal function studies. He had the following lab results: Urine Creatinine 120mg/dL Serum Creatinine 1.5 mg/dL Total Urine volume in 24h 1800/mL Calculate the Creatinine Clearance for this patient in mL/min:
- A.
100
- B.
144
- C.
156
- D.
225
- 62.The parent substance in the biosynthesis of androgens and estrogens is:
- A.
Cortisol
- B.
Catecholamines
- C.
Progesterone
- D.
Cholesterol
- 63.In the Malloy and Evelyn method for the determination of bilirubin, the reagent that is reacted with bilirubin to form a purple azobilirubin is:
- A.
Dilute sulfuric acid
- B.
Diazonium sulfate
- C.
Sulfobromophthalein
- D.
Diazotized sulfanilic acid
- 64.Maple syrup urine disease is characterized by an increase in which of the following urinary amino acids?
- A.
Phenylalanine
- B.
Tyrosine
- C.
Valine, leucine, and isoleucine
- D.
Cystine and cysteine
- 65.Which of the following enzymes catalyzes the conversion of starch to glucose and maltose?
- A.
Malate dehydrogenase (MD)
- B.
Amylase (AMS)
- C.
Creatine kinase (CK)
- D.
Isocitric dehydrogenase (ICD)
- 66.The greatest activities of serum AST and ALT are seen in?
- A.
Acute hepatitis
- B.
Primary Biliary cirrhosis
- C.
Metastatic hepatic carcinoma
- D.
Alcoholic cirrhosis
- 67.Bioavailability of a drug refers to the?
- A.
Availability for therapeutic administration
- B.
Availability of the protein-bound fraction of the drug
- C.
Drug transformation
- D.
The fraction of the drug absorbed into the systemic circulation
- 68.The cyclic antidepressants are classified as?
- A.
Basic drugs
- B.
Neutral drugs
- C.
Acidic Drugs
- D.
Structurally cycloparaffinic
- 69.The most widely employed screening technique for drug abuse is?
- A.
High performance liquid chromatography
- B.
Gas liquid chromatography
- C.
Thin layer chromatography
- D.
UV spectrophotometry
- 70.Phenobarbital is a metabolite of?
- A.
Primidone
- B.
Phenytoin
- C.
Amobarbital
- D.
Secobarbital
- 71.Increased serum albumin concentrations are seen in which of the following conditions?
- A.
Nephrotic syndrome
- B.
Acute hepatitis
- C.
Chronic inflammation
- D.
Dehydration
- 72.Which of the following amino acids is associated with sulfhydryl group?
- A.
Cysteine
- B.
Glycine
- C.
Serine
- D.
Tyrosine
- 73.Night blindness is associated with deficiency of which of the following vitamins?
- A.
A
- B.
C
- C.
Niacin
- D.
Thiamine
- 74.Scurvy is associated with deficiency of which of the following vitamins?
- A.
A
- B.
C
- C.
Niacin
- D.
Thiamine
- 75.A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is?
- A.
Digoxin
- B.
Acetaminophen
- C.
Lithium
- D.
Phenytoin
- 76.Pellagra is associated with deficiency of which of the following vitamins?
- A.
A
- B.
C
- C.
Niacin
- D.
Thiamine
- 77.A drug that relaxes the smooth muscles of the bronchial passages is?
- A.
Acetaminophen
- B.
Lithium
- C.
Phenytoin
- D.
Theophylline
- 78.
- A.
(A unknown/A standard) x C standard
- B.
C standard x A unknown
- C.
A standard x A unknown
- D.
(C standard)/(A standard) x 100
- 79.Which of the following is the formula for coefficient of variation?
- A.
(standard deviation x 100)/standard error
- B.
(mean x 100)/standard deviation
- C.
(standard deviation x 100)/mean
- D.
(variance x 100)/mean
- 80.Rickets is associated with deficiency in which of the following vitamins?
- A.
A
- B.
C
- C.
Niacin
- D.
D
- 81.The regulation of calcium and phosphorus metabolism is accomplished by which of the following glands?
- A.
Thyroid
- B.
Parathyroid
- C.
Adrenal glands
- D.
Pituitary
- 82.Lithium therapy is widely used in the treatment of?
- A.
Hypertension
- B.
Hyperactivity
- C.
Aggression
- D.
Manic-depression
- 83.
- A.
Perform the test immediately upon receipt
- B.
Perform the test only if the specimen was submitted in ice water
- C.
Request a venous blood specimen
- D.
Request a new arterial specimen be obtained
- 84.The anticonvulsant used to control tonic-clonic (grand mal) seizures is?
- A.
Digoxin
- B.
Acetaminophen
- C.
Lithium
- D.
Phenytoin
- 85.A carbonate salt used to control manic-depressive disorders is?
- A.
Digoxin
- B.
Acetaminophen
- C.
Lithium
- D.
Phenytoin
- 86.
- A.
Check the serum for hemolysis
- B.
Rerun the test
- C.
Check the age of the patient
- D.
Do nothing, simply report the result
- 87.Specimens for blood gas determination should be drawn into a syringe containing?
- A.
No preservatives
- B.
Heparin
- C.
EDTA
- D.
Oxalate
- 88.The measurement of light scattered by particles in the sample is the principle of?
- A.
Spectrophotometer
- B.
Fluorometry
- C.
Nephelometry
- D.
Atomic absorption
- 89.Coulometry is used to measure?
- A.
Chloride
- B.
PH
- C.
Bicarbonate
- D.
Ammonia
- 90.The measurement of the amount of electricity passing between two electrodes in an electro-chemical cell is the principle of:
- A.
Electrophoresis
- B.
Amperometry
- C.
Nephelometry
- D.
Coulometry
- 91.Which of the following lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient?
- A.
Cholesterol
- B.
Triglyceride
- C.
HDL
- D.
LDL
- 92.Turbidity in serum suggests elevation of?
- A.
Cholesterol
- B.
Total protein
- C.
Chylomicrons
- D.
Albumin
- 93.Enzyme-multiplied immunoassay techniques (EMIT) differ from all other types of enzyme immunoassays in that?
- A.
Lysozyme is the only enzyme used to label the hapten molecule
- B.
No separation of bound and free antigen is required
- C.
Inhibition of the enzyme label is accomplished with polyethyleneglycol
- D.
Antibody absorption to polystyrene tubes precludes competition to labeled and unlabeled antigen
- 94.The TRH stimulation test is useful in assessing which of the following?
- A.
TRH concentration
- B.
Iodine deficiency
- C.
Depression
- D.
Hyperthyroidism
- 95.Clinical assays for tumor markers are most important for?
- A.
Screening for the presence of cancer
- B.
Monitoring the course of a known cancer
- C.
Confirming the absence of disease
- D.
Identifying patients at risk for cancer
- 96.
- A.
6
- B.
22
- C.
60
- D.
65
- 97.TSH is produced by the?
- A.
Hypothalamus
- B.
Pituitary Gland
- C.
Adrenal Cortex
- D.
Thyroid
- 98.Estrogen and progesterone receptor assays are useful in assessing prognosis in which of the following?
- A.
Ovarian Cancer
- B.
Breast Cancer
- C.
Endometriosis
- D.
Amenorrhea
- 99.Cerebrospinal fluid for glucose assay should be?
- A.
Refrigerated
- B.
Analyzed immediately
- C.
Heated to 56 degrees Celsius
- D.
Stored at room temperature after centrifugation
- 100.An analgesic that alleviates pain without causing loss of consciousness is?
- A.
Digoxin
- B.
Acetaminophen
- C.
Lithium
- D.
Phenytoin
- 101.Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in which of the following diseases?
- A.
Muscular dystrophy
- B.
Viral hepatitis
- C.
Pulmonary emboli
- D.
Infectious mononucleosis
- 102.
- A.
Kidney
- B.
Spleen
- C.
Liver
- D.
Intestine
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