MLT Chemistry Test

102 Questions | Total Attempts: 5276

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  • 1. 
    • A. 

      Free amino acids

    • B. 

      Free carboxyl groups

    • C. 

      Peptide bonds

    • D. 

      Tyrosine residues

  • 2. 
    Calcium concentration in the serum is regulated by?  
    • A. 

      Insulin

    • B. 

      Parathyroid hormone

    • C. 

      Thyroxin

    • D. 

      Vitamin C

  • 3. 
    In the liver, bilirubin is converted to:  
    • A. 

      Urobilinogen

    • B. 

      Urobilin

    • C. 

      Bilirubin-albumin complex

    • D. 

      Bilirubin diglucuronide

  • 4. 
    The osmolality of a urine or serum specimen is measured by a change in the?  
    • A. 

      Freezing point

    • B. 

      Sediment point

    • C. 

      Midpoint

    • D. 

      Osmotic pressure

  • 5. 
    Which of the following steroids is an adrenal cortical hormone?  
    • A. 

      Angiotensinogen

    • B. 

      Corticosterone

    • C. 

      Progesterone

    • D. 

      Pregnanetriol

  • 6. 
    Which two conditions can “physiologically” elevate serum alkaline phosphatase?  
    • A. 

      Rickets, hyperparathyroidism

    • B. 

      Obstructive jaundice

    • C. 

      Growth, third trimester of pregnancy

    • D. 

      Viral hepatitis, infectious mononucleosis

  • 7. 
    • A. 

      A normal finding

    • B. 

      Cushing’s syndrome

    • C. 

      Addison’s disease

    • D. 

      Hypopituitarism

  • 8. 
    In electrophoretic analysis, buffers?  
    • A. 

      Stabilize electrolytes

    • B. 

      Maintain basic PH

    • C. 

      Act as a carrier for ions

    • D. 

      Produce an effect on protein configuration

  • 9. 
    The T3 resin uptake test is a measure of?  
    • A. 

      Circulating T3

    • B. 

      Bound T3

    • C. 

      Binding capacity of thyroxine-binding globulin

    • D. 

      Total thyroxine-binding globulin

  • 10. 
    • A. 

      Direct colorimetric measurement of dissolved CO2

    • B. 

      Calculations of blood PH and total CO2 concentration

    • C. 

      Measurement of CO2-saturated hemoglobin

    • D. 

      Measurement of CO2 consumed at the cathode

  • 11. 
    Which of the following serum constituents is unstable if a blood specimen is left standing at room temperature for 8 hours before processing?  
    • A. 

      Cholesterol

    • B. 

      Triglyceride

    • C. 

      Creatinine

    • D. 

      Glucose

  • 12. 
    Total iron-binding capacity measures the serum iron transporting capacity of?  
    • A. 

      Hemoglobin

    • B. 

      Ceruloplasmin

    • C. 

      Transferrin

    • D. 

      Ferritin

  • 13. 
    In a spectrophotometer, light of a specific wavelength can be isolated from white light with a(n)?  
    • A. 

      Double beam

    • B. 

      Diffraction grating

    • C. 

      Aperture

    • D. 

      Slit

  • 14. 
    Absorbance (A) of a solution may be converted to percent transmittance (%T) using the formula?  
    • A. 

      1 + Log %T

    • B. 

      2 + Log %T

    • C. 

      1 - Log %T

    • D. 

      2 - Log %T

  • 15. 
    A condition in which erythrocyte protoporphyrin is increased is?  
    • A. 

      Acute intermittent porphyria

    • B. 

      Iron Deficiency anemia

    • C. 

      Porphyria cutanea tarda

    • D. 

      Acute porphyric attack

  • 16. 
    • A. 

      2 Na x (Glucose/20) x (BUN/3)

    • B. 

      Na + (2 x Glucose/20) x (BUN/3)

    • C. 

      2 Na + Glucose/20 + (BUN/3)

    • D. 

      2 Na + Glucose/3 + (BUN/20)

  • 17. 
    The first step to be taken when attempting to repair a piece of electronic equipment is?  
    • A. 

      Check all the electronic connections

    • B. 

      Reset all the printed circuit boards

    • C. 

      Turn the instrument off

    • D. 

      Replace all the fuses

  • 18. 
    Most of the carbon dioxide present in the blood is in the form of?  
    • A. 

      Dissolve CO2

    • B. 

      Carbonate

    • C. 

      Bicarbonate ion

    • D. 

      Carbonic acid

  • 19. 
    The statistical term for the average value is the?  
    • A. 

      Mode

    • B. 

      Median

    • C. 

      Mean

    • D. 

      Coefficient of variation

  • 20. 
    An index of precision is statistically known as the?  
    • A. 

      Median

    • B. 

      Mean

    • C. 

      Standard deviation

    • D. 

      Coefficient of variation

  • 21. 
    The most frequent value in a collection of data is statistically known as the?  
    • A. 

      Mode

    • B. 

      Median

    • C. 

      Mean

    • D. 

      Standard deviation

  • 22. 
    The middle value of a data set is statistically known as the?  
    • A. 

      Mean

    • B. 

      Median

    • C. 

      Mode

    • D. 

      Standard deviation

  • 23. 
    In a specimen collected for plasma glucose analysis, sodium floride?  
    • A. 

      Serves as a coenzyme of hexokinase

    • B. 

      Prevents reactivity of non-glucose reducing substances

    • C. 

      Precipitates proteins

    • D. 

      Inhibits glycolysis

  • 24. 
    The serum that contributes to most serum osmolality is?  
    • A. 

      Glucose

    • B. 

      Sodium

    • C. 

      Chloride

    • D. 

      Urea

  • 25. 
    Which family of steroid hormones is characterized by an unsaturated A ring?  
    • A. 

      Progestins

    • B. 

      Estrogens

    • C. 

      Androgens

    • D. 

      Glucocorticoids

  • 26. 
    • A. 

      Alpha-1 globulin

    • B. 

      Alpha1- globulin and alpha-2 globulin

    • C. 

      Alpha-2 globulin and beta globulin

    • D. 

      Beta globulin and gamma globulin

  • 27. 
    The following lab results were obtained from arterial blood: sodium           136 mEq/L pH                   7.32 Potassium     4.4 mEq/L PCO2             79 mm Hg Chloride         92 mEq/L Bicarbonate  40 mEq/L these results are compatible with?  
    • A. 

      Respiratory alkalosis

    • B. 

      Respiratory acidosis

    • C. 

      Metabolic alkalosis

    • D. 

      Metabolic acidosis

  • 28. 
    Which of the following statements about fluorometry are true?  
    • A. 

      A compound is said to fluoresce when it absorbs light at one wavelength and emits light at a second wave length

    • B. 

      Detectors in fluorometers are placed 180 degrees from the excitation source

    • C. 

      It is less sensitive than spectrophotometry

    • D. 

      It avoids the necessity for complexing of components because fluorescence is a native property

  • 29. 
    Two standard deviations is the acceptable limit of error in the chemistry laboratory. If you run the normal control 100 times, how many of the values wou;d be out of control due to random error?  
    • A. 

      1

    • B. 

      5

    • C. 

      10

    • D. 

      20

  • 30. 
    Serum anion gap is increased in patients with?  
    • A. 

      Renal tubular acidosis

    • B. 

      Diabetic alkalosis

    • C. 

      Metabolic acidosis due to diarrhea

    • D. 

      Lactic acidosis

  • 31. 
    The nanometer is used as a measure of?   
    • A. 

      Absorbance

    • B. 

      % transmittance

    • C. 

      Intensity of radiant energy

    • D. 

      Wavelength of radiant energy

  • 32. 
    A common cause of respiratory alkalosis is?  
    • A. 

      Vomiting

    • B. 

      Starvation

    • C. 

      Asthma

    • D. 

      Hyperventilation

  • 33. 
     Major actions of angiotensin II include?  
    • A. 

      Increased pituitary secretion of rennin

    • B. 

      Increased vasoconstriction

    • C. 

      Increased parathyroid hormone secretion by the parathyroid

    • D. 

      Decreased adrenal secretion of aldosterone

  • 34. 
    The anion gap is useful for QC of laboratory results for?  
    • A. 

      Amino acids and proteins

    • B. 

      Blood gas analyses

    • C. 

      Sodium, potassium, chloride, and total CO2

    • D. 

      Calcium, phosphorus, and magnesium

  • 35. 
    Which of the following electrolytes is the chief plasma cation whose main function is maintaining osmotic pressure?  
    • A. 

      Chloride

    • B. 

      Calcium

    • C. 

      Potassium

    • D. 

      Sodium

  • 36. 
    What is the molarity of a solution that contains 18.7 g of KCI (MW=74.5) in 500 ml of water?  
    • A. 

      0.1

    • B. 

      0.5

    • C. 

      1.0

    • D. 

      5.0

  • 37. 
    The buffering capacity of blood is maintained by a reversible exchange process between bicarbonate and?  
    • A. 

      Sodium

    • B. 

      Potassium

    • C. 

      Calcium

    • D. 

      Chloride

  • 38. 
    The different water content of erythrocytes and plasma makes true glucose concentrations in whole blood a function of the?  
    • A. 

      Hematocrit

    • B. 

      Leukocyte count

    • C. 

      Erythrocyte count

    • D. 

      Erythrocyte indices

  • 39. 
    Acidosis and alkalosis are best defined as fluctuations in blood pH and CO2 content due to changes in?  
    • A. 

      Bohr’s effect

    • B. 

      O2 content

    • C. 

      Bicarbonate buffer

    • D. 

      Carbonic anhydrase

  • 40. 
    Metabolic acidosis is described as a(n)?
    • A. 

      Increase in CO2 content and PCO2 with a decreased pH

    • B. 

      Decrease in CO2 content with an increased pH

    • C. 

      Increase in CO2 with and increased pH

    • D. 

      Decrease in CO2 content and PCO2 with a decreased pH

  • 41. 
    The normal range for the pH of arterial blood measured at 37 degrees Celsius is?
    • A. 

      7.28-7.34

    • B. 

      7.33-7.37

    • C. 

      7.35-7.45

    • D. 

      7.45-7.50

  • 42. 
    Hydrogen ion concentration (pH) in blood is usually determined by means of which of the following electrodes?
    • A. 

      Silver

    • B. 

      Glass

    • C. 

      Platinum

    • D. 

      Platinum-lactate

  • 43. 
    The conversion of glucose or other hexoses into lactate or pyruvate is called?  
    • A. 

      Glycogenesis

    • B. 

      Glycogenolysis

    • C. 

      Gluconeogenesis

    • D. 

      Glycolysis

  • 44. 
    A reciprocal relationship exists between?  
    • A. 

      Sodium and potassium

    • B. 

      Calcium and phosphorus

    • C. 

      Chloride and CO2

    • D. 

      Calcium and magnesium

  • 45. 
    Respiratory acidosis is described as a(n)?  
    • A. 

      Increase in CO2 content and PCO2 with a decreased pH

    • B. 

      Decrease in CO2 content with an increased pH

    • C. 

      Increase in CO2 content with an increased pH

    • D. 

      Decrease in CO2 content and PCO2 with a decreased pH

  • 46. 
    Which of the following hemoglobins has glucose-6-phosphate on the amino-terminal valine of the beta chain?  
    • A. 

      S

    • B. 

      C

    • C. 

      A2

    • D. 

      A1c

  • 47. 
    The function of the major lipid components of the very low density lipoproteins (VLDL) is to transport?  
    • A. 

      Cholesterol from peripheral cells to the liver

    • B. 

      Cholesterol and Phospholipids to peripheral cells

    • C. 

      Exogenous triglycerides

    • D. 

      Endogenous triglycerides

  • 48. 
    A hospitalized patient is experiencing increased neuromuscular irritability (tetany). Which of the following tests should be ordered immediately?
    • A. 

      Calcium

    • B. 

      Phosphorus

    • C. 

      BUN

    • D. 

      Glucose

  • 49. 
    Sixty to seventy-five percent of the plasma cholesterol is transported by?  
    • A. 

      Chylomicrons

    • B. 

      VLDL

    • C. 

      LDL

    • D. 

      HDL

  • 50. 
    Measurement of total T4 by competitive protein binding or displacement is based on the specific binding properties of?  
    • A. 

      Thyroxine-binding prealbumin

    • B. 

      Albumin

    • C. 

      Thyroxine-binding globulin

    • D. 

      Thyroid-stimulating hormone

  • 51. 
    Which of the following methods employs a highly specific antibody to thyroxine?  
    • A. 

      Total T4 by competitive protein binding

    • B. 

      T4 by RIA

    • C. 

      T4 by column

    • D. 

      T4 by equilibrium dialysis

  • 52. 
    The extent to which measurements agree with the true value of the quantity being measured is known as?  
    • A. 

      Reliability

    • B. 

      Accuracy

    • C. 

      Reproducibility

    • D. 

      Precision

  • 53. 
    When myocardial infarction occurs, the first enzyme to become elevated is?  
    • A. 

      CK

    • B. 

      LD

    • C. 

      AST

    • D. 

      ALT

  • 54. 
    In the Jaffe reaction, creatinine reacts with?  
    • A. 

      Alkaline sulfasalazine solution to produce an orange-yellow complex

    • B. 

      Potassium iodide to form a reddish-purple complex

    • C. 

      Sodium nitroferricyanide to yield a reddish-brown color

    • D. 

      Alkaline picrate solution to yield and orange-red complex

  • 55. 
    Which of the following represents the end product of purine metabolism in humans?
    • A. 

      AMP and GMP

    • B. 

      DNA and RNA

    • C. 

      Allantoin

    • D. 

      Uric acid

  • 56. 
    The biological most active, naturally occurring androgen is?  
    • A. 

      Androstenedione

    • B. 

      Dehydroepiandrosterone

    • C. 

      Epiandrosterone

    • D. 

      Testosterone

  • 57. 
    Bile acid concentrations are useful to asses?   
    • A. 

      Diabetes mellitus

    • B. 

      Hepatobiliary disease

    • C. 

      Intestinal Malabsorption

    • D. 

      Kidney function

  • 58. 
    Which of the following is secreted by the placenta and used for the early detection of pregnancy?  
    • A. 

      Follicle-stimulating hormone (FSH)

    • B. 

      Human Chorionic gonadotropin (HCG)

    • C. 

      Luteinizing hormone (LH)

    • D. 

      Progesterone

  • 59. 
    Decreased serum iron associated with increased TIBC is compatible with which of the following disease states?  
    • A. 

      Anemia of chronic infection

    • B. 

      Iron deficiency anemia

    • C. 

      Chronic liver disease

    • D. 

      Nephrosis

  • 60. 
    The principle excretory form of nitrogen is?  
    • A. 

      Amino acids

    • B. 

      Creatinine

    • C. 

      Urea

    • D. 

      Uric acid

  • 61. 
    A 45 year old male of average height and weight was admitted to the hospital for renal function studies. He had the following lab results: Urine Creatinine                  120mg/dL Serum Creatinine                1.5 mg/dL Total Urine volume in 24h 1800/mL     Calculate the Creatinine Clearance for this patient in mL/min:
    • A. 

      100

    • B. 

      144

    • C. 

      156

    • D. 

      225

  • 62. 
    The parent substance in the biosynthesis of androgens and estrogens is:
    • A. 

      Cortisol

    • B. 

      Catecholamines

    • C. 

      Progesterone

    • D. 

      Cholesterol

  • 63. 
    In the Malloy and Evelyn method for the determination of bilirubin, the reagent that is reacted with bilirubin to form a purple azobilirubin is:  
    • A. 

      Dilute sulfuric acid

    • B. 

      Diazonium sulfate

    • C. 

      Sulfobromophthalein

    • D. 

      Diazotized sulfanilic acid

  • 64. 
    Maple syrup urine disease is characterized by an increase in which of the following urinary amino acids?  
    • A. 

      Phenylalanine

    • B. 

      Tyrosine

    • C. 

      Valine, leucine, and isoleucine

    • D. 

      Cystine and cysteine

  • 65. 
    Which of the following enzymes catalyzes the conversion of starch to glucose and maltose?  
    • A. 

      Malate dehydrogenase (MD)

    • B. 

      Amylase (AMS)

    • C. 

      Creatine kinase (CK)

    • D. 

      Isocitric dehydrogenase (ICD)

  • 66. 
    The greatest activities of serum AST and ALT are seen in?  
    • A. 

      Acute hepatitis

    • B. 

      Primary Biliary cirrhosis

    • C. 

      Metastatic hepatic carcinoma

    • D. 

      Alcoholic cirrhosis

  • 67. 
    Bioavailability of a drug refers to the?
    • A. 

      Availability for therapeutic administration

    • B. 

      Availability of the protein-bound fraction of the drug

    • C. 

      Drug transformation

    • D. 

      The fraction of the drug absorbed into the systemic circulation

  • 68. 
    The cyclic antidepressants are classified as?  
    • A. 

      Basic drugs

    • B. 

      Neutral drugs

    • C. 

      Acidic Drugs

    • D. 

      Structurally cycloparaffinic

  • 69. 
    The most widely employed screening technique for drug abuse is? 
    • A. 

      High performance liquid chromatography

    • B. 

      Gas liquid chromatography

    • C. 

      Thin layer chromatography

    • D. 

      UV spectrophotometry

  • 70. 
    Phenobarbital is a metabolite of?  
    • A. 

      Primidone

    • B. 

      Phenytoin

    • C. 

      Amobarbital

    • D. 

      Secobarbital

  • 71. 
    Increased serum albumin concentrations are seen in which of the following conditions?  
    • A. 

      Nephrotic syndrome

    • B. 

      Acute hepatitis

    • C. 

      Chronic inflammation

    • D. 

      Dehydration

  • 72. 
    Which of the following amino acids is associated with sulfhydryl group?  
    • A. 

      Cysteine

    • B. 

      Glycine

    • C. 

      Serine

    • D. 

      Tyrosine

  • 73. 
    Night blindness is associated with deficiency of which of the following vitamins?  
    • A. 

      A

    • B. 

      C

    • C. 

      Niacin

    • D. 

      Thiamine

  • 74. 
    Scurvy is associated with deficiency of which of the following vitamins?  
    • A. 

      A

    • B. 

      C

    • C. 

      Niacin

    • D. 

      Thiamine

  • 75. 
    A cardiac glycoside that is used in the treatment of congenital heart failure and arrhythmias by increasing the force and velocity of myocardial contraction is?  
    • A. 

      Digoxin

    • B. 

      Acetaminophen

    • C. 

      Lithium

    • D. 

      Phenytoin

  • 76. 
    Pellagra is associated with deficiency of which of the following vitamins?  
    • A. 

      A

    • B. 

      C

    • C. 

      Niacin

    • D. 

      Thiamine

  • 77. 
    A drug that relaxes the smooth muscles of the bronchial passages is?  
    • A. 

      Acetaminophen

    • B. 

      Lithium

    • C. 

      Phenytoin

    • D. 

      Theophylline

  • 78. 
    • A. 

      (A unknown/A standard) x C standard

    • B. 

      C standard x A unknown

    • C. 

      A standard x A unknown

    • D. 

      (C standard)/(A standard) x 100

  • 79. 
    Which of the following is the formula for coefficient of variation?  
    • A. 

      (standard deviation x 100)/standard error

    • B. 

      (mean x 100)/standard deviation

    • C. 

      (standard deviation x 100)/mean

    • D. 

      (variance x 100)/mean

  • 80. 
    Rickets is associated with deficiency in which of the following vitamins?  
    • A. 

      A

    • B. 

      C

    • C. 

      Niacin

    • D. 

      D

  • 81. 
    The regulation of calcium and phosphorus metabolism is accomplished by which of the following glands?  
    • A. 

      Thyroid

    • B. 

      Parathyroid

    • C. 

      Adrenal glands

    • D. 

      Pituitary

  • 82. 
    Lithium therapy is widely used in the treatment of?  
    • A. 

      Hypertension

    • B. 

      Hyperactivity

    • C. 

      Aggression

    • D. 

      Manic-depression

  • 83. 
    • A. 

      Perform the test immediately upon receipt

    • B. 

      Perform the test only if the specimen was submitted in ice water

    • C. 

      Request a venous blood specimen

    • D. 

      Request a new arterial specimen be obtained

  • 84. 
    The anticonvulsant used to control tonic-clonic (grand mal) seizures is?  
    • A. 

      Digoxin

    • B. 

      Acetaminophen

    • C. 

      Lithium

    • D. 

      Phenytoin

  • 85. 
    A carbonate salt used to control manic-depressive disorders is?
    • A. 

      Digoxin

    • B. 

      Acetaminophen

    • C. 

      Lithium

    • D. 

      Phenytoin

  • 86. 
    • A. 

      Check the serum for hemolysis

    • B. 

      Rerun the test

    • C. 

      Check the age of the patient

    • D. 

      Do nothing, simply report the result

  • 87. 
    Specimens for blood gas determination should be drawn into a syringe containing?  
    • A. 

      No preservatives

    • B. 

      Heparin

    • C. 

      EDTA

    • D. 

      Oxalate

  • 88. 
    The measurement of light scattered by particles in the sample is the principle of?  
    • A. 

      Spectrophotometer

    • B. 

      Fluorometry

    • C. 

      Nephelometry

    • D. 

      Atomic absorption

  • 89. 
    Coulometry is used to measure?  
    • A. 

      Chloride

    • B. 

      PH

    • C. 

      Bicarbonate

    • D. 

      Ammonia

  • 90. 
    The measurement of the amount of electricity passing between two electrodes in an electro-chemical cell is the principle of:
    • A. 

      Electrophoresis

    • B. 

      Amperometry

    • C. 

      Nephelometry

    • D. 

      Coulometry

  • 91. 
    Which of the following lipid results would be expected to be falsely elevated on a serum specimen from a nonfasting patient?
    • A. 

      Cholesterol

    • B. 

      Triglyceride

    • C. 

      HDL

    • D. 

      LDL

  • 92. 
    Turbidity in serum suggests elevation of?  
    • A. 

      Cholesterol

    • B. 

      Total protein

    • C. 

      Chylomicrons

    • D. 

      Albumin

  • 93. 
    Enzyme-multiplied immunoassay techniques (EMIT) differ from all other types of enzyme immunoassays in that?
    • A. 

      Lysozyme is the only enzyme used to label the hapten molecule

    • B. 

      No separation of bound and free antigen is required

    • C. 

      Inhibition of the enzyme label is accomplished with polyethyleneglycol

    • D. 

      Antibody absorption to polystyrene tubes precludes competition to labeled and unlabeled antigen

  • 94. 
    The TRH stimulation test is useful in assessing which of the following?  
    • A. 

      TRH concentration

    • B. 

      Iodine deficiency

    • C. 

      Depression

    • D. 

      Hyperthyroidism

  • 95. 
    Clinical assays for tumor markers are most important for?  
    • A. 

      Screening for the presence of cancer

    • B. 

      Monitoring the course of a known cancer

    • C. 

      Confirming the absence of disease

    • D. 

      Identifying patients at risk for cancer

  • 96. 
    • A. 

      6

    • B. 

      22

    • C. 

      60

    • D. 

      65

  • 97. 
    TSH is produced by the?  
    • A. 

      Hypothalamus

    • B. 

      Pituitary Gland

    • C. 

      Adrenal Cortex

    • D. 

      Thyroid

  • 98. 
    Estrogen and progesterone receptor assays are useful in assessing prognosis in which of the following?
    • A. 

      Ovarian Cancer

    • B. 

      Breast Cancer

    • C. 

      Endometriosis

    • D. 

      Amenorrhea

  • 99. 
    Cerebrospinal fluid for glucose assay should be?  
    • A. 

      Refrigerated

    • B. 

      Analyzed immediately

    • C. 

      Heated to 56 degrees Celsius

    • D. 

      Stored at room temperature after centrifugation

  • 100. 
    An analgesic that alleviates pain without causing loss of consciousness is?
    • A. 

      Digoxin

    • B. 

      Acetaminophen

    • C. 

      Lithium

    • D. 

      Phenytoin

  • 101. 
    Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in which of the following diseases?
    • A. 

      Muscular dystrophy

    • B. 

      Viral hepatitis

    • C. 

      Pulmonary emboli

    • D. 

      Infectious mononucleosis

  • 102. 
    • A. 

      Kidney

    • B. 

      Spleen

    • C. 

      Liver

    • D. 

      Intestine