Mlsp 5112 Micro - Spirochetes
- 1.Which are general characteristics of Leptospira?
- A.
Short tight spirals
- B.
Easy to identify
- C.
Requires dark field microscopy
- D.
Answers 1 and 3
- E.
All of the above
- 2.Leptospirosis is common in rats and can infect humans by coming into contact with infected urine.
- A.
True
- B.
False
- 3.Which is a complication of Leptospirosis and what can prevent it?
- A.
Weil's disease, frequent hand washing
- B.
Jarisch-Herxheimer reaction, low dose antibiotics
- C.
Weil's disease, low dose antibiotics
- D.
Jarisch-Herxheimer, no way to prevent
- 4.What media is used to culture Leptospira?
- A.
Middlebrook media
- B.
PPLO broth
- C.
Fletcher's semi-solid media
- D.
Cell culture
- 5.When doing serological testing of Leptospira, it is important to use killed organism as it is more sensitive than live organism.
- A.
True
- B.
False
- 6.How is Borrelia transferred?
- A.
Via lice or tick
- B.
Via mucous membranes
- C.
Via bodily fluids
- 7.Which organism(s) cause Relapsing Fever?
- A.
Borrelia recurrentis
- B.
Borrelia hermsii
- C.
Borrelia burgdorferi
- D.
Answers 1 and 2
- E.
All of the above
- 8.What causes the recurrent fever episodes in Relapsing Fever?
- A.
New infections
- B.
Neutrophil reaction
- C.
Eosinophilic reaction
- D.
Antigenic variation of surface proteins
- 9.What antibiotic(s) are used to treat Relapsing Fever?
- A.
Amoxicillin
- B.
Erythromycin
- C.
Cephalosporin
- D.
Tetracycline
- 10.The adult Ixodes tick has the best transmission rates for Lyme Disease.
- A.
True
- B.
False
- 11.OspA is an important protein for B.burgdorferi and the pathogenesis of Lyme Disease.
- A.
True
- B.
False
- 12.Culture of B.burgdorferi is the primary method of identification in the laboratory.
- A.
True
- B.
False
- 13.Which organism causes Syphilis.
- A.
T. pertenue
- B.
T. pallidum
- C.
T. carateum
- 14.Which phase(s) are associated with transplacental transfer of syphilis?
- A.
Primary phase
- B.
Secondary phase
- C.
Tertiary phase
- 15.Non-trepanemal serologic testing non-specific and is used as a screening test whereas trepanemal is specific and confirmatory.
- A.
True
- B.
False
- 16.Why can't oral samples be used for direct microscopic examination for syphilis?
- A.
Organism does not live in oral habitats
- B.
Organism is anaerobic
- C.
Contains normal flora treponemes
- D.
All of the above
- 17.A single dose of penicillin is sufficient to treat a syphilis infection.
- A.
True, infection
- B.
True, infection >1 year
- 18.Which of the below are associated with Rat-bite fever.
- A.
Short, thick, tightly coiled spirals
- B.
Common in USA
- C.
Not culturable
- D.
Caused by Spirillium minor
- E.
No serologic testing available
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