Quiz Tekn.Sediaan Solid S1 Farmasi Sem 5

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| By Sri Rahayu
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Sri Rahayu
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Quizzes Created: 1 | Total Attempts: 140
| Attempts: 140 | Questions: 14
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1. Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot tablet dengan cara mengambil 20 sampel acak tablet, kemudian menimbang 20 tablet tersebut dengan hasil sebagai berikut : 155 mg 153 mg 150 mg 152 mg 152 mg 149 mg 151 mg 150 mg 151 mg 150 mg 150 mg 145 mg 152 mg 151 mg 151 mg 159 mg 150 mg 150 mg 153 mg 151 mg Berapa bobot rata-rata tablet tersebut ?  

Explanation

The average weight of the tablets is calculated by adding up the weights of all the tablets and then dividing it by the total number of tablets. In this case, the sum of the weights of the 20 tablets is 3025 mg. Dividing this by 20 gives us an average weight of 151.25 mg. Therefore, the correct answer is 151.25 gram.

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2. Vitamin C dapat dibuat menggunakan metode kempa langsung , karena

Explanation

The correct answer is "Vitamin C mudah teroksidasi karena lembab" because it is stated in the given information that Vitamin C is easily oxidized when exposed to moisture. This implies that the presence of moisture can cause the degradation of Vitamin C, leading to its oxidation.

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3. Parasetamol cocok dibuat tablet dengan metode granulasi basah karena ..............

Explanation

Paracetamol memiliki sifat alir yang kurang bagus, sehingga metode granulasi basah cocok digunakan untuk membuat tablet. Metode granulasi basah melibatkan penambahan cairan ke bahan aktif (paracetamol) untuk membentuk granul yang dapat dengan mudah diubah menjadi tablet. Dalam metode ini, kelebihan cairan membantu meningkatkan aliran bahan aktif yang sulit mengalir, seperti paracetamol, sehingga memungkinkan pembentukan tablet yang lebih kompak.

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4. Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot tablet dengan cara mengambil 20 sampel acak tablet, kemudian menimbang 20 tablet tersebut dengan hasil sebagai berikut : 155 mg 153 mg 150 mg 152 mg 152 mg 149 mg 151 mg 150 mg 151 mg 150 mg 150 mg 145 mg 152 mg 151 mg 151 mg 159 mg 150 mg 150 mg 153 mg 151 mg Berapakah persyaratan penyimpangan pada kolom B?

Explanation

The correct answer is 15%. The requirement for deviation in column B is 15%. This means that the weight of each tablet should not deviate more than 15% from the average weight of the 20 tablets.

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5. Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot tablet dengan cara mengambil 20 sampel acak tablet, kemudian menimbang 20 tablet tersebut dengan hasil sebagai berikut : 155 mg 153 mg 150 mg 152 mg 152 mg 149 mg 151 mg 150 mg 151 mg 150 mg 150 mg 145 mg 152 mg 151 mg 151 mg 159 mg 150 mg 150 mg 153 mg 151 mg Berapa range bobot tablet yang diperbolehkan pada kolom B ?

Explanation

The range of tablet weights allowed in column B is 128.57 - 173.93 mg. This can be determined by finding the minimum and maximum values from the given tablet weights. The minimum weight is 145 mg and the maximum weight is 159 mg. Therefore, the range is 159 mg - 145 mg = 14 mg. Adding this range to the minimum weight gives 145 mg + 14 mg = 159 mg, and subtracting it from the maximum weight gives 159 mg - 14 mg = 145 mg. Therefore, the range of tablet weights allowed in column B is 128.57 - 173.93 mg.

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6. Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot tablet dengan cara mengambil 20 sampel acak tablet, kemudian menimbang 20 tablet tersebut dengan hasil sebagai berikut : 155 mg 153 mg 150 mg 152 mg 152 mg 149 mg 151 mg 150 mg 151 mg 150 mg 150 mg 145 mg 152 mg 151 mg 151 mg 159 mg 150 mg 150 mg 153 mg 151 mg Berapa range bobot tablet yang diperbolehkan pada kolom A ?

Explanation

The range of tablet weight allowed in column A is 139.91 - 162.59 mg. This is determined by finding the difference between the lowest and highest values in the given sample, which is 145 mg and 159 mg respectively. Therefore, the range of acceptable tablet weight falls within the range of 139.91 - 162.59 mg.

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7. Metode granulasi kering cocok untuk ......

Explanation

The dry granulation method is suitable for zat aktif that is sensitive to heat and moisture. This method helps to avoid any potential changes in the zat aktif due to unwanted recrystallization during the drying process. By using the dry granulation method, the zat aktif can be processed without excessive mechanical impact, which is beneficial for zat aktif that is sensitive to excessive mechanical impact. Additionally, this method is also suitable for zat aktif with poor flow properties.

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8. Pengukuran sifat alir secara langsung dapat dilakukan dengan mengukur ....

Explanation

Direct measurement of flow characteristics can be done by measuring the flow time.

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9. Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot tablet dengan cara mengambil 20 sampel acak tablet, kemudian menimbang 20 tablet tersebut dengan hasil sebagai berikut : 155 mg 153 mg 150 mg 152 mg 152 mg 149 mg 151 mg 150 mg 151 mg 150 mg 150 mg 145 mg 152 mg 151 mg 151 mg 159 mg 150 mg 150 mg 153 mg 151 mg Berapakah persyaratan penyimpangan pada kolom A?

Explanation

The correct answer is 7,5%. This is because the requirement for deviation in tablet weight uniformity is typically set at ±5% of the average weight. In this case, the average weight of the 20 tablets is 150 mg. Therefore, the acceptable deviation would be ±7,5 mg (which is 5% of 150 mg).

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10. Faktor yang berpengaruh terhadap keseragaman bobot adalah ...........

Explanation

The flowability of granules can affect the uniformity of weight. If the granules have poor flowability, it can result in uneven distribution of the active ingredient and other excipients, leading to variations in weight. Therefore, the flowability or flow properties of the granules play a significant role in ensuring the uniformity of weight in pharmaceutical manufacturing.

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11. Diketahu tinggi tumpukan serbuk adalah 8 cm dan diameternya adalah 6 cm , maka sudut diam yang terbentuk adalah ....

Explanation

The question provides information about the height and diameter of a stack of powder. To find the angle, we can use trigonometry. The diameter of the stack is the base of a right triangle, and the height is the opposite side. The angle can be found using the inverse tangent function (tan^-1). By substituting the values given (height = 8 cm, diameter = 6 cm) into the formula tan^-1(height/diameter), we can calculate the angle. The correct answer is 69,44.

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12. Parasetamol dapat dibuat secara kempa langsung meskipun sifat alirnya jelak, karena

Explanation

The correct answer suggests that the maximum amount of paracetamol that can be used in the tablet is 30% of its weight. This means that the formulation should not exceed this limit in order to ensure the safety and efficacy of the medication. Using more than 30% of paracetamol may lead to potential side effects or reduced effectiveness of the tablet.

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13. Granul mempunyai sifat alir yang baik jika .......

Explanation

Granul memiliki sifat alir yang baik jika memiliki indeks tap sebesar 15%. Indeks tap adalah ukuran yang digunakan untuk mengevaluasi kemampuan granul dalam mengalir. Semakin tinggi indeks tap, semakin baik kemampuan granul dalam mengalir. Dalam konteks ini, granul dengan indeks tap sebesar 15% memiliki sifat alir yang baik.

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14. Hal yang menjadi pertimbangan ketika memilih metode pembuatan tablet adalah .............

Explanation

When choosing a tablet manufacturing method, one important consideration is compactibility. This refers to the ability of the tablet ingredients to be compressed into a solid and stable form. A tablet that is not compacted properly may crumble or break easily, making it less effective or difficult to handle. Therefore, ensuring that the chosen method can achieve compactibility is crucial for producing high-quality tablets.

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Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot...
Vitamin C dapat dibuat menggunakan metode kempa langsung , karena
Parasetamol cocok dibuat tablet dengan metode granulasi basah karena...
Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot...
Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot...
Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot...
Metode granulasi kering cocok untuk ......
Pengukuran sifat alir secara langsung dapat dilakukan dengan mengukur...
Dalam pembuatan tablet dilakukan evaluasi terhadap keseragaman bobot...
Faktor yang berpengaruh terhadap keseragaman bobot adalah ...........
Diketahu tinggi tumpukan serbuk adalah 8 cm dan diameternya adalah 6...
Parasetamol dapat dibuat secara kempa langsung meskipun sifat alirnya...
Granul mempunyai sifat alir yang baik jika .......
Hal yang menjadi pertimbangan ketika memilih metode pembuatan tablet...
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