Arrhythmias Quiz Part (1)

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1. Under normal circumstances, when a premature impulse is initiated, it cannot be conducted in either direction down either pathway because :

Explanation

When a premature impulse is initiated, the tissue is in its absolute refractory period from the previous impulse. During this period, the tissue is unable to respond to any new stimulus and is temporarily unexcitable. As a result, the premature impulse cannot be conducted in either direction down either pathway. This refractory period allows the tissue to recover and reset its electrical properties before it can be stimulated again.

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About This Quiz
Arrhythmias Quiz Part (1) - Quiz

The 'ARRHYTHMIAS Quiz Part (1)' tests knowledge on heart function, focusing on electrical activity and mechanisms driving blood flow. It assesses understanding of key cardiac components like the... see moreSA node and action potential, crucial for medical and biology students. see less

2. Acute treatment of the symptomatic and/or hemodynamically unstable patient with sinus bradycardia includes administration of :

Explanation

In the acute treatment of a symptomatic and/or hemodynamically unstable patient with sinus bradycardia, administering 0.5 mg of IV Atropine is recommended. Atropine is a medication that helps increase heart rate by blocking the action of the vagus nerve, which slows down the heart. By administering Atropine intravenously, it can quickly act on the body and increase the heart rate, improving symptoms and stabilizing the patient's condition.

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3. Abnormal initiation of electrical impulses occurs as a result of abnormal automaticity

Explanation

Abnormal initiation of electrical impulses refers to the generation of electrical signals in the heart at irregular times or locations. This can lead to irregular heart rhythms or arrhythmias. Abnormal automaticity refers to the ability of certain cells in the heart to spontaneously generate electrical impulses, which can disrupt the normal electrical conduction system. Therefore, it is true that abnormal automaticity can result in abnormal initiation of electrical impulses.

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4. The pacemaker of the heart is not the SA node

Explanation

The pacemaker of the heart is the SA node, also known as the sinoatrial node. This small group of cells located in the right atrium of the heart initiates electrical impulses that regulate the heart's rhythm and rate. These impulses then travel through the atria and ventricles, causing them to contract and pump blood. Therefore, the correct answer is False.

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5. The SA node has the greatest degree of automaticity

Explanation

The SA node, also known as the sinoatrial node, is located in the right atrium of the heart and is responsible for initiating the electrical impulses that regulate the heart rhythm. It has the highest degree of automaticity among all the cardiac cells, meaning it has the ability to generate electrical impulses spontaneously without any external stimulation. This automaticity allows the SA node to set the pace for the rest of the heart, making it the natural pacemaker of the heart. Therefore, the statement "The SA node has the greatest degree of automaticity" is true.

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6. During phase 2, potassium ions continue to exit the cell, but the membrane potential is balanced by an influx of calcium and sodium ions, transported through slow calcium and slow sodium channels, resulting in a plateau.

Explanation

During phase 2 of the cardiac action potential, the membrane potential is balanced by the exit of potassium ions from the cell. However, this exit is counteracted by the influx of calcium and sodium ions through slow calcium and slow sodium channels. This balanced movement of ions results in a plateau phase, which is a characteristic feature of phase 2. Therefore, the statement is true.

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7. CARDIAC ARRHYTHMIAS Cardiac arrhythmias are classified into two broad categories: supraventricular (those occurring above the ventricles) and ventricular (those occurring in the ventricles).

Explanation

The statement is true because cardiac arrhythmias are indeed classified into two broad categories: supraventricular and ventricular. Supraventricular arrhythmias occur above the ventricles, which include the atria and the atrioventricular node. Ventricular arrhythmias, on the other hand, occur in the ventricles of the heart. This classification helps in understanding the location and origin of different types of arrhythmias, which in turn helps in determining the appropriate treatment strategies.

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8. The mechanism of abnormal impulse conduction is traditionally referred to as :

Explanation

not-available-via-ai

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9. During phase 3, the efflux of potassium ions greatly exceeds calcium and sodium influx, resulting in the major component of ventricular repolarization.

Explanation

During phase 3 of the cardiac action potential, the efflux (outward movement) of potassium ions is much higher than the influx (inward movement) of calcium and sodium ions. This leads to the repolarization of the ventricles, which is the process of restoring the electrical potential of the heart muscle cells back to their resting state after contraction. Therefore, the statement that the efflux of potassium ions greatly exceeds calcium and sodium influx during phase 3, resulting in the major component of ventricular repolarization, is true.

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10. Myocardial ischemia does not alter impulse conduction velocity

Explanation

Myocardial ischemia refers to a condition where there is a lack of blood flow and oxygen supply to the heart muscle. This can result in various changes in the heart, including a decrease in the conduction velocity of electrical impulses. When the heart muscle is deprived of oxygen, it becomes less efficient in conducting electrical signals, leading to abnormalities in the heart's rhythm and potentially causing arrhythmias. Therefore, the statement that myocardial ischemia does not alter impulse conduction velocity is incorrect.

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11. These three conditions are  (1) at least two pathways for the impulse to travel  (2) a "unidirectional block" in one of the conduction pathways                                                                                     (3) slowing of the velocity of impulse conduction down the other conduction pathway.

Explanation

The explanation for the given correct answer is that for reentry to occur, there must be at least two pathways for the impulse to travel. This allows the impulse to continue circulating in a circuit, leading to a sustained abnormal rhythm. Additionally, there must be a "unidirectional block" in one of the conduction pathways, meaning that the impulse can only travel in one direction in that pathway. Finally, the velocity of impulse conduction must be slowed down in the other conduction pathway, further promoting the reentry circuit. These three conditions together create the necessary conditions for reentry to occur.

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12. In patients with hemodynamically unstable sinus bradycardia unresponsive to atropine, transcutaneous pacing may be initiated.

Explanation

Transcutaneous pacing is a temporary method used to treat hemodynamically unstable sinus bradycardia. It involves the application of electrical impulses to the chest wall to stimulate the heart and increase the heart rate. Atropine is a medication commonly used to treat bradycardia, but if it is ineffective, transcutaneous pacing can be initiated as an alternative treatment option. Therefore, the statement is true.

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13. Ventricular myocyte resting membrane potential is usually –70 to –90 mV

Explanation

The resting membrane potential of ventricular myocytes is typically between -70 to -90 mV. This means that the inside of the cell is more negatively charged compared to the outside. This electrical gradient is important for the normal functioning of the heart, as it allows for the generation and propagation of action potentials, which are essential for cardiac contraction and rhythm.

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14. He class I drugs are subdivided into classes IA, IB, and IC

Explanation

The statement is true because class I drugs are indeed subdivided into classes IA, IB, and IC. Class I drugs are a category of drugs that affect the action potential of cardiac cells and are used to treat certain heart conditions. The subdivision into classes IA, IB, and IC is based on their specific effects on cardiac cells and their mechanisms of action. This categorization helps in understanding the different properties and therapeutic uses of these drugs.

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15. Class IV drugs are the calcium channel blockers (CCBs), diltiazem and verapamil

Explanation

The statement is true because class IV drugs, such as diltiazem and verapamil, are indeed calcium channel blockers (CCBs). These medications work by blocking the calcium channels in the heart and blood vessels, leading to relaxation of the smooth muscles and dilation of the blood vessels. This helps to lower blood pressure and reduce the workload on the heart. Diltiazem and verapamil are commonly used to treat conditions such as high blood pressure, angina, and certain heart rhythm disorders.

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16. Abnormal atrial automaticity will not result premature atrial contractions, atrial tachycardia or atrial fibrillation

Explanation

Abnormal atrial automaticity can result in premature atrial contractions, atrial tachycardia, or atrial fibrillation. This is because abnormal automaticity refers to the generation of electrical impulses by the atrial tissue outside of the normal pacemaker cells. These abnormal impulses can disrupt the normal electrical activity of the atria, leading to irregular or rapid heart rhythms such as premature contractions, tachycardia, or fibrillation. Therefore, the statement that abnormal atrial automaticity will not result in these conditions is false.

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17. If the patient is taking any medication(s) that may cause symptomatic sinus bradycardia, they should be discontinued whenever possible. If the patient remains in sinus bradycardia after drug discontinuation and after five half-lives of the drug(s) have elapsed, then the drugs(s) can usually be excluded as the etiology of the arrhythmia

Explanation

If a patient is taking medication that is known to cause symptomatic sinus bradycardia, it is recommended to discontinue the medication whenever possible. This is because the medication could be the cause of the bradycardia. If the patient's heart rate remains slow even after stopping the medication and after a sufficient amount of time has passed (five half-lives of the drug), it is likely that the medication is not the cause of the bradycardia. Therefore, the statement "If the patient remains in sinus bradycardia after drug discontinuation and after five half-lives of the drug(s) have elapsed, then the drugs(s) can usually be excluded as the etiology of the arrhythmia" is true.

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18. The class IC drugs have the greatest potency for slowing ventricular conduction

Explanation

Class IC drugs are a type of antiarrhythmic medication that are known to have the greatest potency for slowing ventricular conduction. These drugs work by blocking sodium channels in the heart, which helps to slow down the electrical signals that control the heart's rhythm. By slowing ventricular conduction, these drugs can be effective in treating certain types of abnormal heart rhythms, such as ventricular tachycardia. Therefore, the statement that class IC drugs have the greatest potency for slowing ventricular conduction is true.

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19. Cardiac arrhythmias are caused by

Explanation

Cardiac arrhythmias can be caused by abnormal impulse initiation, meaning that the electrical signals that regulate the heartbeat are not generated properly. They can also be caused by abnormal impulse conduction, where the electrical signals are not transmitted correctly through the heart. Therefore, both of these factors can contribute to the development of cardiac arrhythmias.

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20. A premature impulse may be conducted down both pathways if it is only slightly premature and arrives after the tissue is no longer refractory

Explanation

A premature impulse refers to an electrical signal that occurs earlier than expected in the heart. In this case, the explanation states that if the impulse is only slightly premature and arrives after the tissue is no longer refractory, it can be conducted down both pathways. This means that the electrical signal can travel through both normal and abnormal pathways in the heart. Therefore, the statement is true.

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21. When the membrane potential reaches this threshold, the fast sodium channels open, allowing sodium ions to enter the cell rapidly

Explanation

When the membrane potential reaches the threshold, it triggers the opening of fast sodium channels. This allows sodium ions to flow into the cell rapidly. This influx of positive ions depolarizes the cell and generates an action potential, which is a rapid change in the membrane potential. Therefore, the statement is true.

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22. In patients with hemodynamically unstable or severely symptomatic sinus bradycardia unresponsive to atropine and in whom temporary or transvenous pacing is not available you can use :

Explanation

Patients with hemodynamically unstable or severely symptomatic sinus bradycardia may require immediate intervention when atropine and temporary or transvenous pacing are not available. Isoproterenol, dopamine, and epinephrine are all potential treatment options in such cases. Isoproterenol is a beta-adrenergic agonist that increases heart rate and cardiac output. Dopamine is a catecholamine that can stimulate beta-1 adrenergic receptors and increase heart rate. Epinephrine is also a catecholamine with similar effects on heart rate and cardiac output. Therefore, all three options can be used as alternatives in the management of hemodynamically unstable or severely symptomatic sinus bradycardia.

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23. Class III drugs are those that inhibit ventricular repolarization and prolong refractoriness

Explanation

Class III drugs are a category of antiarrhythmic medications that work by inhibiting ventricular repolarization and prolonging refractoriness. This means that they delay the time it takes for the heart's ventricles to reset after each heartbeat, which can help to prevent abnormal heart rhythms. Therefore, the statement that class III drugs inhibit ventricular repolarization and prolong refractoriness is true.

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24. Atropine should not be used cautiously in patients with myocardial ischemia or MI

Explanation

Atropine should be used cautiously in patients with myocardial ischemia or MI. This is because atropine can increase heart rate and worsen ischemia or MI by increasing the oxygen demand of the heart. Therefore, it is important to monitor these patients closely and use atropine with caution, if necessary.

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25. Class IA drugs have intermediate potency, and class IB drugs have the lowest potency

Explanation

This statement is true because class IA drugs have intermediate potency, meaning they have a moderate level of effectiveness or strength. On the other hand, class IB drugs have the lowest potency, indicating that they have the least amount of effectiveness or strength compared to other classes of drugs. Therefore, the statement accurately describes the potency levels of class IA and class IB drugs.

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26. Which one do you like?

Explanation

not-available-via-ai

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27. This rapid influx of positive ions creates a vertical upstroke of the action potential. This previous is considered as phase 0, which represents ventricular depolarization. At this point, the fast sodium channels become inactivated.

Explanation

During an action potential, the rapid influx of positive ions, particularly sodium ions, causes the depolarization of the ventricles. This depolarization is referred to as phase 0. As the positive ions enter the cell, the fast sodium channels responsible for their entry become inactivated. Therefore, the statement that the fast sodium channels become inactivated during phase 0 is true.

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28. Amiodarone is a drug that is classified as :

Explanation

Amiodarone is classified as Class III antiarrhythmic drug. Class III drugs primarily work by blocking potassium channels, which prolongs the action potential duration and refractory period of cardiac cells. This helps to stabilize the rhythm of the heart and prevent abnormal heartbeats. Amiodarone is commonly used to treat various types of arrhythmias, including atrial fibrillation and ventricular tachycardia. It has a broad spectrum of action and can affect multiple ion channels, which is why it is classified as Class III.

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29. Class II drugs are (Alpha) blockers 

Explanation

They are (Beta) blockers not (Alpha)

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30. Phase 1 repolarization occurs primarily as a result of an influx of potassium ions.

Explanation

efflux not influx

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31. Class (I) drugs primarily increase ventricular automaticity and speed up conduction velocity.

Explanation

Class (I) drugs primarily decrease ventricular automaticity and slow down conduction velocity. These drugs are used to treat abnormal heart rhythms by suppressing the electrical activity in the heart. By reducing the automaticity and conduction velocity, Class (I) drugs help to stabilize the heart's rhythm and prevent arrhythmias. Therefore, the given statement that Class (I) drugs primarily increase ventricular automaticity and speed up conduction velocity is false.

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32. Lidocaine & Mexiletin are classified into calss

Explanation

Lidocaine and Mexiletin are classified as Class IB antiarrhythmic drugs. Class IB drugs primarily work by blocking sodium channels in the heart, which helps to decrease the excitability and conduction of electrical impulses. This class of drugs is particularly effective in treating ventricular arrhythmias, such as ventricular tachycardia and ventricular fibrillation. They have a fast onset of action and a short duration of effect. Class IB drugs have a moderate effect on the duration of the action potential and can help to stabilize the heart's electrical activity.

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33. Sinus bradycardia, originating in the SA node, is defined by a sinus rate less than 50 beats/min

Explanation

60 beats

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34. Ventricular depolarization begins, consisting of phases 1 through 3 of the action potential.

Explanation

repolarization not depolarization

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35. During phase 4, Calcium ions gradually enter the cell, increasing the threshold again to –60 to –80 mV and initiating another action potential.

Explanation

sodium ions not calcium

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36. During each action potential cycle, the potential of the membrane rapidly increases to a threshold potential due to a rapid influx of sodium into the cell

Explanation

Slow increase - Slow influx

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Under normal circumstances, when a premature impulse is initiated, it...
Acute treatment of the symptomatic and/or hemodynamically unstable...
Abnormal initiation of electrical impulses occurs as a result of...
The pacemaker of the heart is not the SA node
The SA node has the greatest degree of automaticity
During phase 2, potassium ions continue to exit the cell, but the...
CARDIAC ARRHYTHMIAS Cardiac arrhythmias are classified into two broad...
The mechanism of abnormal impulse conduction is traditionally referred...
During phase 3, the efflux of potassium ions greatly exceeds calcium...
Myocardial ischemia does not alter impulse conduction velocity
These three conditions are  (1) at least two pathways for the...
In patients with hemodynamically unstable sinus bradycardia...
Ventricular myocyte resting membrane potential is usually –70 to...
He class I drugs are subdivided into classes IA, IB, and IC
Class IV drugs are the calcium channel blockers (CCBs), diltiazem and...
Abnormal atrial automaticity will not result premature atrial...
If the patient is taking any medication(s) that may cause symptomatic...
The class IC drugs have the greatest potency for slowing ventricular...
Cardiac arrhythmias are caused by
A premature impulse may be conducted down both pathways if it is only...
When the membrane potential reaches this threshold, the fast sodium...
In patients with hemodynamically unstable or severely symptomatic...
Class III drugs are those that inhibit ventricular repolarization and...
Atropine should not be used cautiously in patients with myocardial...
Class IA drugs have intermediate potency, and class IB drugs have the...
Which one do you like?
This rapid influx of positive ions creates a vertical upstroke of the...
Amiodarone is a drug that is classified as :
Class II drugs are (Alpha) blockers 
Phase 1 repolarization occurs primarily as a result of an influx of...
Class (I) drugs primarily increase ventricular automaticity and speed...
Lidocaine & Mexiletin are classified into calss
Sinus bradycardia, originating in the SA node, is defined by a sinus...
Ventricular depolarization begins, consisting of phases 1 through 3 of...
During phase 4, Calcium ions gradually enter the cell, increasing the...
During each action potential cycle, the potential of the membrane...
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