Micro - Virology- The Viruses

32 Questions | By Chinedua | Last updated: Jan 21, 2013 | Total Attempts: 198

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Review quiz on microbiology- the viruses covering picornoviruses, enteroviruses, poliviruses, rhinoviruses, and arboviruses

Questions and Answers

1.

Which virus(es) can be considered positive sense?
- A.
  
  Picornoviruses
- B.
  
  Rhinoviruses
- C.
  
  Enteroviruses
- D.
  
  A & B
- E.
  
  All of the above
2.

Which of the following is true about poliovirus
- A.
  
  Can be asymptomatic
- B.
  
  Usually does not affect CNS
- C.
  
  Can cause flaccid paralysis
- D.
  
  A & C
- E.
  
  All of the above
3.

Enteroviruses are spread through which of the following routes
- A.
  
  Contaminated aerosol droplets
- B.
  
  Fecal oral contamination
- C.
  
  Penetration of skin and mucosa
- D.
  
  Inhalation
4.

A patient presents with poliovirus infection and is hospitalized for 4 days. On the second day she appears to have recovered with all labs within normal limits except that she is still shedding polivirus. this is problematic because of which of the following possibilities?
- A.
  
  May develop flaccid paralysis
- B.
  
  Illness has not subsided
- C.
  
  May develop flaccid paralysis
- D.
  
  This can lead to epidemics
5.

Polivirus can infect any organ that it comes in contact with
- A.
  
  True
- B.
  
  False
6.

Which of the following is true about poliovirus replication?
- A.
  
  Uses a RNA dependent DNA polymerase
- B.
  
  Attaches to receptors before replication
- C.
  
  Cannot replicate in small intestines
- D.
  
  Is negative sense single stranded RNA
7.

Which places are the first sites of enterovirus infection
- A.
  
  Intestine and oropharynx
- B.
  
  Blood stream
- C.
  
  Lymphatic system
- D.
  
  Skin
8.

Poliovirus's damage stage features which of the following conditions?
- A.
  
  Flaccid paralysis from destruction of posterior spinal cord
- B.
  
  Replication in any part of neurons
- C.
  
  Causes lytic destruction of host cell tissue
- D.
  
  A & C
9.

Hyper angina is best described by which of the following conditions?
- A.
  
  Caused by enterovirus 71 and coxsackievirus type A16
- B.
  
  Sudden onset of fever with vesicles on tonsils and palate
- C.
  
  Caused by replication of rhinoviruses
- D.
  
  None of the above
10.

Enterovirus and coxsackievirus are not linked to Type 1 Diabetes Mellitus
- A.
  
  True
- B.
  
  False
11.

Which of the following is true about diagnosis of picornoviruses?
- A.
  
  Need to be grown on chocolate agar plates
- B.
  
  Reverse transcription PCR are often ineffective
- C.
  
  Cell cultures are used
- D.
  
  Season, climate and epidemics are irrelevant
12.

A pt presents with polio infection which of the following is the best treatment?
- A.
  
  Antiviral drug therapy
- B.
  
  Salk vaccine IV
- C.
  
  Sabin vaccine PO
- D.
  
  Immunoglobulin injections
13.

A patient presents with a mild upper respiratory illness. The most common cause of this acute illness is ?
- A.
  
  Poliovirus
- B.
  
  Rhinovirus
- C.
  
  Coxsackievirus
- D.
  
  Arbovirus
14.

Rhinovirus can infect with which of the following conditions
- A.
  
  Aerosol and direct contact
- B.
  
  Fecal oral route
- C.
  
  Small inoculum
- D.
  
  A & C
- E.
  
  Insect bite
15.

Which receptors must rhinovirus bind to to cause infection
- A.
  
  ICAM1 and CD155
- B.
  
  PVR and VLDL
- C.
  
  VLDL and ICAM1
- D.
  
  PVR and CD155
16.

Which similarity is shared between polivirus and rhinovirus
- A.
  
  Need to bind to receptors to replicate
- B.
  
  Cause host tissue damage
- C.
  
  Tropism for posterior pharynx
- D.
  
  A & B
17.

VLDL is the receptor for major serotypes if rhinovirus infection
- A.
  
  True
- B.
  
  False
18.

Which of the following treatments are used for rhinoviruses?
- A.
  
  Antivirals/ nasal sprays
- B.
  
  Sabin/ salk vaccine
- C.
  
  Self limiting, no drug therapy available
- D.
  
  Heat to 30 degrees celcius
19.

Rhinovirus shows tropism for the intestinal tract
- A.
  
  True
- B.
  
  False
20.

Which virus causes SARS?
- A.
  
  Rhinovirus
- B.
  
  Coronavirus
- C.
  
  Arbovirus
- D.
  
  None of the aboce
21.

Which property allows corona virus to mutate and adapt during epidemics?
- A.
  
  Ingested in contaminated foods
- B.
  
  MRNA synthesized in short templates
- C.
  
  DNA is incorporated into hosts DNA
- D.
  
  DNA polymerase jumps templates and causes erros
22.

Which of the following is true about arboviruses?
- A.
  
  Excludes bunyaviridae
- B.
  
  Can cause asymptomatic infection
- C.
  
  Spread by aerosols
- D.
  
  Rarely spread by insect bites
23.

Which of the following conditions is most likely to reduce arbovirus infections?
- A.
  
  Virus spreading to salivary glands of insect
- B.
  
  Asymptomatic carriers
- C.
  
  Warm climates
- D.
  
  Cold climate
24.

Which of the following is a site of entrance for arboviruses but not enteroviruses?
- A.
  
  Capillaries
- B.
  
  Ingestion
- C.
  
  CNS
- D.
  
  Intestines
25.

Which of the following is not caused by arboviruses?
- A.
  
  SARS
- B.
  
  WNV
- C.
  
  Hemorraghic fever
- D.
  
  Rash and arthritis