Micro: Toxins And Such

17 Questions | Total Attempts: 50

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Micro: Toxins And Such - Quiz

Questions and Answers
  • 1. 
    What codes for proteins of exotoxins?
    • A. 

      Chromosomes

    • B. 

      SsDNA

    • C. 

      MRNA

    • D. 

      Plasmids

  • 2. 
    Activation of toxins without altering antigenicity results in successful vaccines.
    • A. 

      True

    • B. 

      False

  • 3. 
    What toxin(s) are internalized for activation of the A subunit?
    • A. 

      Tetanus and botulinum

    • B. 

      Cholera and diphtheria

    • C. 

      Staphylococcus

    • D. 

      Diphtheria and botulinum

  • 4. 
    Diphtheria blocks the transfer of _____ _____ to polypeptide chains during ______ of mRNA by ribosomes.
    • A. 

      Amino acids; transcrption

    • B. 

      Adenosine diphosphate; translation

    • C. 

      Amino acids; translation

    • D. 

      Adenosine diphosphate; transcription

  • 5. 
    The cholera toxin inhibits the regulatory mechanism of?
    • A. 

      ATP

    • B. 

      CAMP

    • C. 

      Protein kinase A

    • D. 

      GTP

  • 6. 
    What exotoxin is active at low does and extrememly potent?
    • A. 

      Tetanus

    • B. 

      Cholera

    • C. 

      Diphtheria

    • D. 

      LPS

  • 7. 
    Tetanus affects inhibitory neurons causing continuous stimulation to motor neurons.
    • A. 

      True

    • B. 

      False

  • 8. 
    Botulinum toxin ____ neurotransmitter function of ____ terminals.
    • A. 

      Inhibits; postsynaptic

    • B. 

      Inhibits; presynaptic

    • C. 

      Increases; postsynaptic

    • D. 

      Increases; presynaptic

  • 9. 
    Endotoxins are only released when the cell dies.
    • A. 

      True

    • B. 

      False

  • 10. 
    What bacteria release LPS?
    • A. 

      Gram positve

    • B. 

      Streptococci

    • C. 

      Gram negative

    • D. 

      Staphylococci

  • 11. 
    Which best represents the composition of LPS?
    • A. 

      Lipid B, core polysaccharide, variable O-polysaccharide

    • B. 

      Lipid A, core monosaccharide, variable O-monosaccharide

    • C. 

      Lipid B, core monosaccharide, variable O-monosaccharide

    • D. 

      Lipid A, core polysaccharide, variable O-polysaccharide

  • 12. 
    What cytokines are the primary cause of fever? And they're produced by what cell?
    • A. 

      IL-5, IL-12; eosinophils

    • B. 

      IL-2, IL-1; T cells

    • C. 

      IFN-gamma, TNF; macrophages

    • D. 

      TNF, IL-1; macrophages

  • 13. 
    What structure in the brain to cytokines act on to produce fever?
    • A. 

      Midbrain

    • B. 

      Hypothalamus

    • C. 

      Brainstem

    • D. 

      Thalamus

  • 14. 
    What are the most important effects of LPS?
    • A. 

      Fever and cell lysis

    • B. 

      Cell lysis and shock

    • C. 

      Fever and shock

  • 15. 
    What bacteria is the most common endotoxic shock with septicemia?
    • A. 

      E. coli

    • B. 

      S. aureus

    • C. 

      Shigella

    • D. 

      Salmonella

  • 16. 
    Toxic shock syndrome is caused by ______ infections of the _____.
    • A. 

      Staphylococcus; intestinal

    • B. 

      Staphylococcus; genital

    • C. 

      Streptococcus; intestinal

    • D. 

      Streptococcus; genital

  • 17. 
    After direct activation of completment by LPS, C3a and C5a components are produced in large quantities. This can cause aggregation of PMNs in the pulmonary capillaries resulting in a severe condtion called ____.
    • A. 

      Acute eosinophilic pneumonia

    • B. 

      Adult respiratory distress syndrome

    • C. 

      Acute hypersensitivity pneumonitis

    • D. 

      Noncardiogenic pulmonary edema

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