Dosing Problems

1. The dose of a drug for children based on body surface are based on

Weight and age

Weight and height

Age and height

Age

2. How many colchicines tablets, each containing 600 mcg, may be prepared from 30 g of colchicines?

50,000 tablets

20,000 tablets

55,000 tablets

25,000 tablets

3. An initial dose of not less than 150 units/kg of body weight has been recommended for open heart surgery. How many mL of an injection containing 5000 heparin units per mL should be administered to a 300-lb patient?

3.5 mL

4.1 mL

4.5 mL

5 mL

4. If 10 mg of a drug are added to a 500 mL large-volume parenteral fluid, what should be the rate of flow, in mL/hour, to deliver 1 mg of drug per hour?

500 ml/hr

50 mL/ hr

25 mL/ hr

250 mL/ hr

5. Acetazolamide sodium is available in 500-mg vials to be reconstituted to 5 mL with sterile water for injection prior to use. The dose of the drug for children is 5mg/ kg of body weight. How many mL of the injection should be administered to a child weighing 25 lbs?

0.59 mL

6.9 mL

0.69 mL

0.57 mL

6. Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. How many milliliters would provide dose of 40 mcg?

0.04mL

40L

40mL

0.4mL

7. The usual dose of digoxin for rapid digitalization is a total of 1.0 mg, divide into two or more portions at intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50 mcg/ mL would provide this dose?

25 mL

20 mL

5 mL

15 mL

8. A child weighing 25 lbs is to receive 5 mg of phenytoin per kg of body weight daily as anticonvulsant. How many mL of pediatric phenytoin suspension containing 30 mg per 5 mL should this child receive?

5.5

7.5

6.5

9.47

9. The pediatric dose of cefadroxil is 30 mg/kg/day. If a child is given a daily dose of 2 teaspoonfuls of a suspension containing 125 mg of cefadroxil per 5 mL, what is the weight in lb. of the child?

18.8

18.5

18.3

19

10. Acetazolamide sodium is available in 500-mg vials to be reconstituted to 5 mL with sterile water for injection prior to use. The dose of the drug for children is 5mg/ kg of body weight. How many mL of the injection should be administered to a child weighing 25 lbs?

1mL

0.67 mL

0.75 mL

0.57mL

11. If the adult dose of a drug is 90 mg, what should be the dose for a child with a body surface area of 0.60 sq. m.?

31.21 mg

54mg

150 mg

540 mg

12. In dosing the drug gentamicin in pediatric patients, for every 1 mg/kg of gentamicin administered, serum drug concentrations are expected to increase by 2.5mcg/mL. What would be the expected serum drug concentration following an administration of a 2.5 mg/kg dose of gentamicin?

5 mcg/ml

7.5 mcg/ml

6.25 mcg/ml

3.34 mcg/mL

13. Physicians prefer the calculation of doses for children based on:

Age

BSA

Weight

Height

14. Prescription calls for 250 mL of a liquid medicine contains 0.025 g of atropine sulfate and specific dose of 5 mL . Each dose contains ____ mg of atropine sulfate

0.0005

0.5

5

25

15. A physician orders meprobamate 0.2 g. How much is to be administered if the dose on hand is 400 mg in each tablet?

Do not dispense

Give 2 tablets

Give 1 tablet

Give 1/2 tablet