Hardest Test On Microbiology! Trivia Quiz

73 Questions | Total Attempts: 242

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Microbiology Quizzes & Trivia

The quiz you see below is considered one of the hardest microbiology quizzes to be made in the history of quizzes and it is not to be tackled by anyone who doubts their ability when it comes to Microbiology. Take it up and see just where you stand when compared to the best of the best in all things microbiology.


Questions and Answers
  • 1. 
    A mutation from the most prevalent form of a gene to a mutant form is called a __________ mutation.  
    • A. 

      Forward

    • B. 

      Reverse

    • C. 

      Wild card

    • D. 

      Escalating

  • 2. 
    A mutagen that inserts between the stacked bases of a DNA double helix, distorting the DNA to induce single-pair insertions or deletions is called a(n) __________ agent.  
    • A. 

      Insertional

    • B. 

      Interspersing

    • C. 

      Intercalating

    • D. 

      Distortional

  • 3. 
    Spontaneous mutations are caused by  
    • A. 

      Errors in DNA replication

    • B. 

      Insertion of transposons

    • C. 

      Radiation

    • D. 

      Errors in DNA replication and insertion of transposons

    • E. 

      All of the choices

  • 4. 
    A __________ mutation does not alter the amino acid sequence of the resulting protein.  
    • A. 

      Missense

    • B. 

      Nonsense

    • C. 

      Silent

    • D. 

      None of the choices

  • 5. 
    • A. 

      Transversion

    • B. 

      Transition

    • C. 

      Frameshift

    • D. 

      Insertion

  • 6. 
    Which of the following can lead to transition mutations?  
    • A. 

      Incorporation of a base analog that exhibits different base-pairing properties from the base it replaces

    • B. 

      Chemical modification of an existing base in the DNA so that in the next round of replication it will pair differently from the unmodified base

    • C. 

      Incorporation of a base analog that exhibits different base-pairing properties from the base it replaces and chemical modification of an existing base in the DNA so that in the next round of replication it will pair differently from the unmodified base


    • D. 

      A small insertion or deletion

  • 7. 
    Which of the following is considered a reverse mutation that will restore the wild type phenotype?  
    • A. 

       true reversion back to the wild type base sequence

    • B. 

      Mutation to a different base sequence, but one that restores the amino acid sequence in the protein to the wild type sequence

    • C. 

      A mutation that restores the function of a protein even though it does not restore the base sequence or the amino acid sequence to the wild type

    • D. 

      All of the choices

  • 8. 
    Which of the following types of mutation may play an important role in driving evolution because they are often nonlethal and, therefore, remain in the gene pool?  
    • A. 

      Nonsense

    • B. 

      Missense

    • C. 

      Frameshift

    • D. 

      Deletion

  • 9. 
    A mutation that changes the amino acid sequence of the resulting protein by substitution is called a __________ mutation.  
    • A. 

      Missense

    • B. 

      Nonsense

    • C. 

      Silent

    • D. 

      None of the choices

  • 10. 
    _______ are strains that are unable to grow on a minimal medium that supports growth of the wild type strain but are able to grow on the minimal medium if one or more nutritional supplements are added.  
    • A. 

      Autotrophs

    • B. 

      Auxotrophs

    • C. 

      Portotrophs

    • D. 

      Minitrophs

  • 11. 
    Mutations that result in the death of an organism when expressed are called __________ mutations.  
    • A. 

      Dominant

    • B. 

      Recessive

    • C. 

      Lethal

    • D. 

      Conditional

  • 12. 
    Lethal mutations can be maintained in diploid organisms if they are  
    • A. 

      Dominant

    • B. 

      Recessive

    • C. 

      Deletions

    • D. 

      None of the choices

  • 13. 
    Lethal mutations can be recovered in haploid organisms if they are  
    • A. 

      Dominant

    • B. 

      Active

    • C. 

      Conditional

    • D. 

      None of the choices

  • 14. 
    A __________ mutation is one that causes premature termination of the synthesis of the protein product.  
    • A. 

      Missense

    • B. 

      Nonsense

    • C. 

      Silent

    • D. 

      None of the choices

  • 15. 
    The __________ __________ is the most prevalent form of a gene in a population. (2 words)  
  • 16. 
    __________ are physical or chemical agents that cause mutation.  
  • 17. 
    __________ mutations affect only a single base pair in a gene.  
  • 18. 
    Mutations resulting from exposure to physical or chemical agents are called __________ mutations.  
  • 19. 
    __________ mutations occur in the promoter or operator region of a gene or set of genes and affects the expression of the downstream genes without affecting the amino acid sequences of the gene products.  
  • 20. 
    Microbial strains that can grow on minimal medium are called __________.  
    • A. 

      Autotrophs

    • B. 

      Auxotrophs

    • C. 

      Prototrophs

    • D. 

      Minitrophs

  • 21. 
    Which one of the following contributes to the utility of the strains of Salmonella typhimurium used in the Ames reversion assay?  
    • A. 

      They are highly permeable to test substances.

    • B. 

      They are defective in DNA repair and, therefore, cannot readily repair damage done by the test substances.

    • C. 

      It is very straightforward to assay the conversion of their histidine auxotrophy mutations to histidine prototrophy.

    • D. 

      All of the choices

  • 22. 
    The Ames test  
    • A. 

      Can be used to measure the mutagenicity of chemicals.

    • B. 

      Is used to measure the repair of thymine dimers.

    • C. 

       is used to measure levels of oxygen free radicals.

    • D. 

      None of the choices

  • 23. 
    In mismatch repair on newly replicated DNA, enzymes distinguish between old and newly replicated DNA strands based on the fact that newly replicated DNA strands are ________ methylated relative to older DNA.  
  • 24. 
    Photoreactivation repairs thymine dimers by splitting them back into separate thymines.  
    • A. 

      True

    • B. 

      False

  • 25. 
    Approximately half of known animal carcinogens can be detected by the Ames test.  
    • A. 

      True

    • B. 

      False