Pathogens and Diseases: Identification and Implications in Healthcare

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| Questions: 29 | Updated: Aug 4, 2025
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1. Which tick-borne infection common in North America presents with a red rash, constitutional symptoms, chronic arthritis, and CNS effects?

Explanation

Borrelia burgdorferi is the causative agent of Lyme disease, characterized by a red rash known as erythema migrans, constitutional symptoms like fever and fatigue, chronic arthritis, and central nervous system effects. Anaplasma phagocytophilum and Ehrlichia chaffeensis cause diseases similar to Rocky Mountain spotted fever, while Powassan virus can lead to severe neurological symptoms.

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About This Quiz
Pathogens And Diseases: Identification And Implications In Healthcare - Quiz

Explore the world of medical microbiology, focusing on common microorganisms. This quiz enhances your understanding of pathogens, their identification, and implications in healthcare, making it vital for students and professionals in medical and life sciences.

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2. Which disease is transmitted by ticks and lice and presents with high fever followed by hypotension and drop in temperature, confirmed by peripheral blood smear with Gemsa or Wright staining?

Explanation

Relapsing fever is caused by Borrelia species which are transmitted by ticks and lice. The characteristic symptoms include high fever, hypotension, and a drop in temperature. Diagnosis is confirmed by examining peripheral blood smear with Gemsa or Wright staining, showing the presence of Borrelia organisms.

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3. Which bacteria is responsible for food poisoning/intoxication, toxin mediated skin syndrome, and hospital acquired infections, often resistant to many antibiotics? It typically infects wounds or catheters and many people are carriers. It is a Coagulase-positive Gram-positive coccus.

Explanation

Staphylococcus aureus is a common bacterium that can cause a range of infections in humans. It is known for causing food poisoning, skin infections, and hospital-acquired infections. It is often resistant to many antibiotics, making treatment challenging. The bacterium can infect wounds or catheters, and many people can be carriers of the bacteria without displaying symptoms.

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4. Coagulase -ve, gram +ve coccus. Opportunistic infection often found in blood. Part of the normal flora of skin. Forms biofilms on plastic. Can cause endocarditis peritonitis bacterimia.

Explanation

The correct answer is Staphylococcus epidermidis, a common species of bacteria that fits the description provided in the question. Streptococcus pyogenes, Clostridium difficile, and Escherichia coli are other bacterial species with distinct characteristics and clinical presentations.

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5. Normal GI flora, coagulase -ve gram +ve coccus. 2nd most common UTI in females. Surface adherens facilitate attachment.

Explanation

Staphylococcus saprophyticus is the correct answer as it is a coagulase-negative Gram-positive coccus commonly found in the genitourinary tract. It is the second most common cause of urinary tract infections in females due to its ability to adhere to urinary tract surfaces. Escherichia coli, Streptococcus pyogenes, and Enterococcus faecalis are incorrect choices as they are not commonly associated with urinary tract infections caused by surface adherens facilitating attachment.

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6. Which Gram-negative bacterium causes diarrhea, fever, vomiting, and abdominal cramps through fecal-oral transmission from contaminated foods, avoids destruction in the stomach, and colonizes the ileum and cecum with flagellum and pili?

Explanation

Salmonella enterica is a pathogenic bacterium often associated with foodborne illnesses. It is known to cause symptoms such as diarrhea, fever, vomiting, and abdominal cramps. Salmonella is able to evade destruction in the stomach and can colonize the ileum and cecum using its flagellum and pili. Escherichia coli, Campylobacter jejuni, and Shigella flexneri are other bacteria that can also cause gastrointestinal symptoms but do not match all the characteristics mentioned in the question.

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7. Which of the following bacteria is gram-negative cocci that is motile, contains pili, and is sexually transmitted causing symptoms such as purulent discharge and burning sensation when urinating?

Explanation

Neisseria gonorrhoeae fits the description provided in the question, as it is a gram-negative cocci bacterium that is motile and contains pili. It is transmitted sexually and commonly causes symptoms such as purulent discharge from the genitals and burning sensation during urination. Chlamydia trachomatis is a different bacterium that causes similar symptoms but does not fit all the characteristics described in the question. Treponema pallidum causes syphilis, which is a different sexually transmitted infection. Haemophilus ducreyi, on the other hand, causes chancroid, another sexually transmitted infection, but does not match all the features mentioned in the question.

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8. Which of the following pathogens is characterized by gram negative diplococci, respiratory route through aerosolized particles, symptoms of meningitis such as neck stiffness and altered mental status (manic behavior), and sudden onset of fever, nausea, vomiting, headache, and myalgia?

Explanation

Neisseria meningitidis is the correct answer as it is a Gram-negative diplococci bacterium known to cause meningitis. Streptococcus pneumoniae is a common cause of pneumonia and otitis media. Haemophilus influenzae can cause respiratory infections but is not typically associated with the symptoms described. Legionella pneumophila causes Legionnaires' disease, which presents with symptoms like pneumonia and gastrointestinal issues, but does not typically lead to symptoms of meningitis.

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9. Which of the following pathogens is a gram-negative rod, facultative anaerobe, non-motile, and transmitted through the respiratory route in aerosol droplets?

Explanation

Haemophilus influenza fits all the given characteristics, including being a gram-negative rod, facultative anaerobe, non-motile, and transmitted through the respiratory route. It can cause meningitis, bacteremia, lethargy, and vomiting. LPS can cause an inflammatory response, and its capsule prevents phagocytosis and IgA protease.

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10. Which sexually transmitted infection is transmitted by intercourse and oral sex and from mother to daughter? Primary infection presents as a chancre at the site of infection followed by system symptoms with a rash on the palms and soles of the feet.

Explanation

Syphilis, caused by Treponema pallidum, is commonly transmitted through sexual contact and from mother to child during pregnancy. The primary infection is characterized by a painless sore called a chancre, followed by secondary symptoms including a rash on the palms and soles of the feet. This distinguishes syphilis from other sexually transmitted infections like Gonorrhea, Chlamydia, and Herpes simplex virus (HSV-2).

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11. Which bacterium has an end-hook that allows for better attachment to the host, is found in tropical and temperate regions, and is often present in kidney tubules, with transmission occurring from infected animal urine or the environment?

Explanation

Leptospira interrogans fits the description provided in the question, with its unique characteristics and transmission methods matching the given details.

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12. Which coagulase-negative gram-positive coccus, part of normal skin flora, can cause skin or soft tissue infections as well as endocarditis?

Explanation

Staphylococcus lugdunensis is a coagulase-negative gram-positive coccus that is commonly found in the normal skin flora. It has been known to cause skin or soft tissue infections as well as endocarditis.

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13. Which coagulase-negative gram-positive coccus, part of normal skin flora, can cause skin or soft tissue infections as well as wound infections?

Explanation

While Staphylococcus haemolyticus is a coagulase-negative gram-positive coccus, it is not typically associated with skin infections. Streptococcus pyogenes and Enterococcus faecalis are also gram-positive cocci but are not part of the normal skin flora and are more commonly associated with other types of infections.

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14. Which bacterial pathogen is responsible for Scarlet Fever, pharyngitis, necrotizing fasciitis, and rheumatic fever, all of which can be transmitted directly from person to person?

Explanation

These incorrect answers are not responsible for the mentioned diseases caused by Streptococcus pyogenes.

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15. Gram +ve bacteria belonging to the lactic acid bacteria group. Coccus Neonates pheumonia sepsis and meningtis. Droplet transmission.

Explanation

Streptococcus agalactiae is the correct answer as it fits all the criteria mentioned in the question, including being a Gram +ve coccus bacterium causing neonatal pneumonia, sepsis, and meningitis. It is primarily transmitted through droplet transmission. Streptococcus pyogenes, Streptococcus pneumoniae, and Staphylococcus aureus are not specific to the characteristics mentioned in the question.

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16. Gram +ve bacteria belonging to the lactic acid bacteria group causing Pneumonia, Meningitis, and Otitis media through droplet transmission.

Explanation

Streptococcus pneumoniae is a common Gram +ve bacteria that causes respiratory infections such as pneumonia, meningitis, and otitis media through droplet transmission. The other incorrect options belong to different bacterial species that are not specifically known for causing these types of infections.

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17. Which bacterium is a Gram-negative bacillus that is aerobic, a commensal bacteria in large intestine, motile with peritrichous flagellae, transmitted fecal-orally, causes gastroenteritis and produces heat stable/labile enterotoxin which prevents water absorption in intestinal cells, is responsible for 90% of UTIs, and causes neonatal meningitis?

Explanation

Escherichia coli matches all the characteristics mentioned in the question, making it the correct answer. Salmonella enterica is also responsible for gastrointestinal infections, but does not match all the other characteristics. Staphylococcus aureus is a Gram-positive bacterium and does not cause the specific illnesses mentioned. Clostridium difficile is an anaerobic bacterium known for causing antibiotic-associated diarrhea, but doesn't match the rest of the characteristics mentioned for the correct answer.

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18. Gram-negative facultative anaerobe transmitted in contaminated food or water. Produces diarrhea, abdominal pain, and fever. Infects small bowel and proximal large bowel. Can invade to the basolateral side, replicate within macrophages, avoid innate immune response, and form granulomas and microabscesses.

Explanation

The correct answer is Yersinia enterocolitica, as it fits the descriptions provided in the question. Salmonella typhi causes typhoid fever, Clostridium difficile causes antibiotic-associated diarrhoea, and Vibrio cholerae causes cholera, which are not consistent with the symptoms and characteristics mentioned in the question.

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19. Which Gram-negative non-motile bacterium ferments glucose but not lactose, is transmitted person to person via the fecal-oral route, causes watery and possibly bloody stools, and uses an actin tail to spread?

Explanation

Shigella is a bacterium known for causing bacillary dysentery in humans, whereas Salmonella, E. coli, and Campylobacter are other common bacterial causes of foodborne illnesses, but do not match all the specific characteristics described in the question.

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20. What is the causative agent of Black Death which is gram-negative, non-motile and transmitted from rodent fleas handling infected bodies or bites from infected cats or rodents, leading to fever, chills, headache, and death in 90% of patients as it travels to lymph nodes and multiplies to form buboes?

Explanation

The correct answer is Yersinia pestis, as it is the bacterium responsible for causing the plague known as Black Death. The other options, Escherichia coli, Staphylococcus aureus, and Clostridium tetani, are not associated with the specific characteristics and transmission methods mentioned in the question.

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21. Gram-negative coccobacillus obligate aerobic transmitted by respiratory route. Contains a toxin which stops cilia from beating and toxins that block macrophages. Presents with 5+ coughs at a time followed by high-pitched whooping sounds, runny nose, sneezing, low-grade fever. Typically diagnosed via swab testing.

Explanation

Bordetella pertussis is the causative agent of whooping cough, or pertussis, which is characterized by the symptoms described in the question. Haemophilus influenzae, Mycoplasma pneumoniae, and Legionella pneumophila are other bacteria that can cause respiratory infections but do not match the specific characteristics mentioned in the question.

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22. Which gram-negative coccobacillus, sexually transmitted and enters skin through a break in epithelial cells, causes painful erythematous papules that can burst and cause ulcers?

Explanation

Haemophilus ducreyi is the correct answer as it is the causative agent of chancroid, a sexually transmitted infection characterized by painful genital ulcers. Neisseria gonorrhoeae is a gram-negative diplococcus responsible for gonorrhea, which presents with urethritis or cervicitis. Treponema pallidum is a spirochete bacterium that causes syphilis, presenting with various stages of skin and mucosal lesions. Chlamydia trachomatis is an obligate intracellular bacterium that causes chlamydia, which can lead to urethritis, cervicitis, and pelvic inflammatory disease.

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23. Identify the gram-negative bacterium with curved rod shape and polar flagella, facultative anaerobes, transmitted by consumption of fecal contaminated drinking water, which colonizes the small intestine and secretes a toxin that activates G protein causing high cAMP and CFTR activation leading to severe dehydrating diarrhea with a death rate of 25-50% in untreated patients.

Explanation

Vibrio Cholerae O1 is the correct answer as it fits all the characteristics described in the question. Salmonella typhi is responsible for causing typhoid fever, and does not match the description. Escherichia coli can cause diarrhea but does not match all the specific characteristics given. Shigella dysenteriae is a different bacterium that causes dysentery, not cholera.

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24. Gram-negative bacteria with curved rod shape and polar flagella. Facultative anaerobes. Transmitted mainly through contaminated food same as O1 but usually not fatal.

Explanation

Vibrio cholerae non-O1 matches the description provided, while Salmonella, Escherichia coli, and Campylobacter jejuni are other common foodborne pathogens with different characteristics.

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25. Gram-negative with curved rod shape and polar flagella. Facultative anaerobes. Acquired when swimming with open wounds in infected water or after eating undercooked seafood. Releases capsular polysaccharide that triggers TNF alpha. Rapidly expanding cellulitis if wound infected. Vomiting diarrhea if foodborne.

Explanation

Vibrio vulnificus is a bacterium known for causing infections through the routes described in the question. Escherichia coli is a common bacterium found in the gastrointestinal tract and can cause various infections, but not typically associated with the described characteristics. Salmonella typhi is the causative agent of typhoid fever, transmitted through contaminated food and water. Pseudomonas aeruginosa is an opportunistic pathogen found in moist environments, known for causing infections in immunocompromised individuals.

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26. Which gram-negative bacteria has a curved rod shape and polar flagella, is a facultative anaerobe, and is acquired from undercooked shellfish or through consumption of cecal contaminated drinking water/food, causing mild to moderate gastroenteritis with symptoms such as diarrhea and abdominal pain?

Explanation

Vibrio parahaemolyticus is a gram-negative bacterium with a curved rod shape and polar flagella. It is a facultative anaerobe and is commonly acquired from undercooked shellfish or through the consumption of contaminated water or food. This bacterium can cause mild to moderate gastroenteritis with symptoms such as diarrhea and abdominal pain. Salmonella enterica, Campylobacter jejuni, and Escherichia coli are other bacteria that can cause gastroenteritis but do not match the specific characteristics described in the question.

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27. What is the name of the Gram-negative obligate intracellular bacteria that is non-motile, non-spore forming, aerobic, highly pathogenic, and transmitted by ticks and fleas? This disease occurs in the Americas and is characterized by symptoms such as headache, fever, muscle pain, nausea, vomiting, rash on soles and palms of feet, and a black spot in the middle of the rash where the bite occurred.

Explanation

Rocky Mountain spotted fever is caused by Rickettsia rickettsii, a Gram-negative obligate intracellular bacteria that is transmitted by ticks and fleas. The disease presents with specific symptoms and occurs in the Americas. Lyme disease is caused by Borrelia burgdorferi and transmitted by ticks, while Ehrlichiosis is caused by Anaplasma phagocytophilum and is also transmitted by ticks. Tularemia is caused by Francisella tularensis and can be transmitted through various routes including ticks.

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28. Gram-negative obligate intracellular bacteria, non-motile, non-spore forming aerobes that are highly pathogenic. Transmitted by feces of human body louse that enters via cut or skin abrasion. Occurs in regions of crowded cold unhygienic locations. Symptoms include severe fever, headache, pain, nausea, diarrhea, macular flat rash from trunk to extremities. Some patients have confusion or seizures.

Explanation

Rickettsia prowazekii causes Epidemic Typhus which matches the description given in the question. Borrelia burgdorferi causes Lyme disease which is transmitted by ticks, Yersinia pestis causes Plague transmitted by fleas, and Mycobacterium tuberculosis causes Tuberculosis which is not transmitted by body lice as described in the question.

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29. Gram -ve obligate intracellular bacteria non-motile non-spore forming aerobes highly pathogenic. transmitted by mites that live on house mice. occurs in urban areas. disease is mild and self-limited. Skin lesion where bite occurred, abrupt onset of fever and constitutional symptoms papulovesicular rash.

Explanation

Rickettsia akari causes Rickettsialpox, which matches the description provided in the question. Yersinia pestis causes Plague, Bartonella henselae causes Cat Scratch Fever, and Francisella tularensis causes Tularemia, which do not fully align with the characteristics mentioned in the question.

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Which tick-borne infection common in North America presents with a red...
Which disease is transmitted by ticks and lice and presents with high...
Which bacteria is responsible for food poisoning/intoxication, toxin...
Coagulase -ve, gram +ve coccus. Opportunistic infection often found in...
Normal GI flora, coagulase -ve gram +ve coccus. 2nd most common UTI in...
Which Gram-negative bacterium causes diarrhea, fever, vomiting, and...
Which of the following bacteria is gram-negative cocci that is motile,...
Which of the following pathogens is characterized by gram negative...
Which of the following pathogens is a gram-negative rod, facultative...
Which sexually transmitted infection is transmitted by intercourse and...
Which bacterium has an end-hook that allows for better attachment to...
Which coagulase-negative gram-positive coccus, part of normal skin...
Which coagulase-negative gram-positive coccus, part of normal skin...
Which bacterial pathogen is responsible for Scarlet Fever,...
Gram +ve bacteria belonging to the lactic acid bacteria group. Coccus...
Gram +ve bacteria belonging to the lactic acid bacteria group causing...
Which bacterium is a Gram-negative bacillus that is aerobic, a...
Gram-negative facultative anaerobe transmitted in contaminated food or...
Which Gram-negative non-motile bacterium ferments glucose but not...
What is the causative agent of Black Death which is gram-negative,...
Gram-negative coccobacillus obligate aerobic transmitted by...
Which gram-negative coccobacillus, sexually transmitted and enters...
Identify the gram-negative bacterium with curved rod shape and polar...
Gram-negative bacteria with curved rod shape and polar flagella....
Gram-negative with curved rod shape and polar flagella. Facultative...
Which gram-negative bacteria has a curved rod shape and polar...
What is the name of the Gram-negative obligate intracellular bacteria...
Gram-negative obligate intracellular bacteria, non-motile, non-spore...
Gram -ve obligate intracellular bacteria non-motile non-spore forming...
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