To solve the inequality 4(x - 1) + 3 > 15, we first distribute 4 to the terms inside the parentheses, resulting in 4x - 4 + 3 > 15. Simplifying further, we get 4x - 1 > 15. Adding 1 to both sides, we have 4x > 16. Finally, dividing both sides by 4, we find that x > 4. Therefore, the correct answer is x > 4.