BRS Endocrine Physiology Quiz: Trivia!

30 Questions | Total Attempts: 57

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BRS Endocrine Physiology Quiz: Trivia!

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Questions and Answers
  • 1. 
    The increase shown at point A is caused by the effect of
    • A. 

      Estrogen on the anterior pituitary

    • B. 

      Progesterone on the hypothalamus

    • C. 

      Follicle-stimulating hormone (FSH) on the ovary

    • D. 

      Luteinizing hormone (LH) on the anterior pituitary

    • E. 

      Prolactin on the ovary

  • 2. 
    Blood levels of which substance are described by curve B?
    • A. 

      Estradiol

    • B. 

      Estriol

    • C. 

      Progesterone

    • D. 

      FSH

    • E. 

      LH

  • 3. 
    The source of the increase in concentration indicated at point C is the
    • A. 

      Hypothalamus

    • B. 

      Anterior pituitary

    • C. 

      Corpus luteum

    • D. 

      Ovary

    • E. 

      Adrenal cortex

  • 4. 
    The source of the increase in concentrationat point D is the
    • A. 

      Ovary

    • B. 

      Adrenal cortex

    • C. 

      Corpus luteum

    • D. 

      Hypothalamus

    • E. 

      Anterior pituitary

  • 5. 
    The cause of the sudden increase shown at point E is
    • A. 

      Negative feedback of progesterone on the hypothalamus

    • B. 

      Negative feedback of estrogen on the anterior pituitary

    • C. 

      Negative feedback of follicle-stimulating hormone (FSH) on the ovary

    • D. 

      Positive feedback of FSH on the ovary

    • E. 

      Positive feedback of estrogen on the anterior pituitary

  • 6. 
    A woman has hypocalcemia, hyperphosphatemia, and decreased urinary phosphate excretion. Injection of parathyroid hormone (PTH) causes an increase in urinary cyclic adenosine monophosphate (cAMP). The most likely diagnosis is
    • A. 

      Primary hyperparathyroidism

    • B. 

      Vitamin D intoxication

    • C. 

      Vitamin D deficiency

    • D. 

      Hypoparathyroidism after thyroid surgery

    • E. 

      Pseudohypoparathyroidism

  • 7. 
    Which of the following hormones acts on its target tissues by a steroid hormone mechanism of action?
    • A. 

      Thyroid hormone

    • B. 

      Parathyroid hormone (PTH)

    • C. 

      Antidiuretic hormone (ADH) on the collecting duct

    • D. 

      Rl adrenergic agonists

    • E. 

      Glucagon

  • 8. 
    A man who has galactorrhea is found to have a prolactinoma. His physician treats him with bromocriptine, which eliminates the galactorrhea. The basis for the therapeutic action of bromocriptine is that it
    • A. 

      Antagonizes the action of prolactin on the breast

    • B. 

      Enhances the action of prolactin on the breast

    • C. 

      Inhibits prolactin release from the anterior pituitary

    • D. 

      Inhibits prolactin release from the hypothalamus

    • E. 

      Enhances the action of dopamine on the anterior pituitary

  • 9. 
    Which of the following hormones originates in the anterior pituitary?
    • A. 

      Dopamine

    • B. 

      Growth hormone releasing hormone (GHRH)

    • C. 

      Somatostatin

    • D. 

      Gonadotropin-releasing hormone (GnRH)

    • E. 

      Thyroid-stimulating hormone (TSH)

    • F. 

      Oxytocin

    • G. 

      Testosterone

  • 10. 
    Which of the following functions of the Sertoli cells mediates negative feedback control of follicle-stimulating hormone (FSH) secretion?
    • A. 

      Synthesis of inhibin

    • B. 

      Synthesis of testosterone

    • C. 

      Aromatization of testosterone

    • D. 

      Maintenance of the blood—testes barrier

  • 11. 
    Which of the following substances is derived from proopiomelanocortin (POMC)?
    • A. 

      Adrenocorticotropic hormone (ACTH)

    • B. 

      Follicle-stimulating hormone (FSH)

    • C. 

      Melatonin

    • D. 

      Cortisol

    • E. 

      Dehydroepiandrosterone

  • 12. 
    Which of the following inhibits the secretion of growth hormone by the anterior pituitary?
    • A. 

      Sleep

    • B. 

      Stress

    • C. 

      Puberty

    • D. 

      Somatomedins

    • E. 

      Starvation

    • F. 

      Hypoglycemia

  • 13. 
    Selective destruction of the zona glomerulosa of the adrenal cortex would produce a deficiency of which hormone?
    • A. 

      Aldosterone

    • B. 

      Androstenedione

    • C. 

      Cortisol

    • D. 

      Dehydroepiandrosterone

    • E. 

      Testosterone

  • 14. 
    Which of the following explains the suppression of lactation during pregnancy?
    • A. 

      Blood prolactin levels are too low for milk production to occur

    • B. 

      Human placental lactogen levels are too low for milk production to occur

    • C. 

      The fetal adrenal gland does not produce sufficient estriol

    • D. 

      Blood levels of estrogen and progesterone are high

    • E. 

      The maternal anterior pituitary is suppressed

  • 15. 
    Which step in steroid hormone biosynthesis, if inhibited, blocks the production of all androgenic compounds but does not block the production of glucocorticoids?
    • A. 

      Cholesterol —> pregnenolone

    • B. 

      Progesterone —> 11-deoxycorticosterone

    • C. 

      17-Hydroxypregnenolone —> dehydroepiandrosterone

    • D. 

      Testosterone -, estradiol

    • E. 

      Testosterone —> dihydrotestosterone

  • 16. 
    A woman has hirsutism, hyperglycemia, obesity, muscle wasting, and increased circulating levels of adrenocorticotropic hormone (ACTH). The most likely cause of her symptoms is
    • A. 

      Primary adrenocortical insufficiency (Addison's disease)

    • B. 

      Pheochromocytoma

    • C. 

      Primary overproduction of ACTH (Cushing's disease)

    • D. 

      Treatment with exogenous glucocorticoids

    • E. 

      Hypophysectomy

  • 17. 
    Which of the following decreases the conversion of 25-hydroxycholecalciferol to 1,25- dihydroxycholecalciferol?
    • A. 

      A diet low in Ca2+

    • B. 

      Hypocalcemia

    • C. 

      Hyperparathyroidism

    • D. 

      Hypophosphatemia

    • E. 

      Chronic renal failure

  • 18. 
    Increased adrenocorticotropic hormone (ACTH) secretion would be expected in patients
    • A. 

      With chronic adrenocortical insufficiency (Addison's disease)

    • B. 

      With primary adrenocortical hyperplasia

    • C. 

      Who are receiving glucocorticoid for immunosuppression after a renal transplant

    • D. 

      With elevated levels of angiotensin II

  • 19. 
    Which of the following would be expected in a patient with Graves' disease?
    • A. 

      Cold sensitivity

    • B. 

      Weight gain

    • C. 

      Decreased 02 consumption

    • D. 

      Decreased cardiac output

    • E. 

      Drooping eyelids

    • F. 

      Atrophy of the thyroid gland

    • G. 

      Increased thyroid-stimulating hormone (TSH) levels

    • H. 

      Increased triiodothyronine (r3) levels

  • 20. 
    Blood levels of which of the following substances is decreased in Graves' disease?
    • A. 

      Triiodothyronine (T3)

    • B. 

      Thyroxine (r,)

    • C. 

      Diiodotyrosine (DIT)

    • D. 

      Thyroid-stimulating hormone (TSH)

    • E. 

      Iodide (I-)

  • 21. 
    Which of the following hormones acts by an inositol 1,4,5-triphosphate (IP 3)-Ca2+ mechanism of action?
    • A. 

      1,25-Dihydroxycholecalciferol

    • B. 

      Progesterone

    • C. 

      Insulin

    • D. 

      Parathyroid hormone (PTH)

    • E. 

      Gonadotropin-releasing hormone (GnRH)

  • 22. 
    Which step in steroid hormone biosynthesis is stimulated by adrenocorticotropic hormone (ACTH)?
    • A. 

      Cholesterol-* pregnenolone

    • B. 

      Progesterone —> 11-deoxycorticosterone

    • C. 

      17-Hydroxypregnenolone dehydroepiandrosterone

    • D. 

      Testosterone —> estradiol

    • E. 

      Testosterone -+ dihydrotestosterone

  • 23. 
    The source of estrogen during the second and third trimesters of pregnancy is the
    • A. 

      Corpus luteum

    • B. 

      Maternal ovaries

    • C. 

      Fetal ovaries

    • D. 

      Placenta

    • E. 

      Maternal ovaries and fetal adrenal gland

    • F. 

      Maternal adrenal gland and fetal liver

    • G. 

      Fetal adrenal gland, fetal liver, and placenta

  • 24. 
    Which of the following causes increased aldosterone secretion?
    • A. 

      Decreased blood volume

    • B. 

      Administration of an inhibitor of angiotensin-converting enzyme (ACE)

    • C. 

      Hyperosmolarity

    • D. 

      Hypokalemia

  • 25. 
    Secretion of oxytocin is increased by
    • A. 

      Milk ejection

    • B. 

      Dilation of the cervix

    • C. 

      Increased prolactin levels

    • D. 

      Increased extracellular fluid (ECF) volume

    • E. 

      Increased serum osmolarity