The given trinomial can be factored as (x + 1)(x + 4). This can be determined by using the FOIL method, which states that when multiplying two binomials, the product is equal to the sum of the products of the First terms, Outer terms, Inner terms, and Last terms. In this case, the First terms are x and x, the Outer terms are x and 4, the Inner terms are 1 and x, and the Last terms are 1 and 4. When simplified, the sum of these products is x^2 + 5x + 4, which matches the original trinomial. Therefore, (x + 1)(x + 4) is the correct answer.