Quiz: How Well Do You Know About Allelic Variation?

Huntington disease and neurofibromatosis are

• A.

  Autosomal recessive

• B.

  Autosomal dominant

• C.

  X-linked recessive

• D.

  Mitochondrial inheritance

• E.

  X-linked dominant

Sickle Cell, phenylketonuria, and cystic fibrosis are

• A.

  Autosomal recessive

• B.

  X-linked recessive

• C.

  Autosomal dominant

• D.

  X-linked dominant

• E.

  Mitochondrial inheritance

Mechanisms of mutation include

• A.

  Nucleotide subsituttions

• B.

  Deletions and insertions

• C.

  Trinucleotide repeat expansions

• D.

  A and C only

• E.

  A, B, and C

Duchenne muscular dystrophy, color blindness, and hemophilia A are

• A.

  X-linked dominant

• B.

  X-linked recessive

• C.

  Mitochondrial inheritance

• D.

  Autosomal dominant

• E.

  Autosomal recessive

RFLP, VNTR, STR, and SNP are

• A.

  Classes of DNA polymorphisms

• B.

  Used for paternity testing

• C.

  Types of HPLC machines

• D.

  Types of mutations

• E.

  Classes of proteins

_________________ inheritance predominantly or exclusively affects males, but there is NO male-to-male transmission.

________________ inheritance is transmitted only through mothers.

When all daughters of an affected father are affected, the mode of transmission is

• A.

  Autosomal recessive

• B.

  Autosomal dominant

• C.

  Mitochondrial

• D.

  X-linked dominant

• E.

  X-linked recessive