Genetics Chapter 3

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Genetics Chapter 3


Questions and Answers
  • 1. 

    Alleles, genes, and loci are different names for the same thing.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 2. 

    The probability of two or more independent events occurring together is calculated by multiplying their independent probabilities.  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 3. 

    The phenotype of a dominant allele is never seen in the F1 progeny of a monohybrid cross.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 4. 

    A Mendelian dihybrid cross involves one gene and two different alleles.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 5. 

    The occurrences of partial expressivity and incomplete penetrance demonstrate that gene expression can be influenced by non-genetic factors  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 6. 

    Mendel did his genetic work with peas in a Viennese monastery.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 7. 

    The principle of independent assortment can be demonstrated using a monohybrid cross.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 8. 

    A single gene can only have two alleles.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 9. 

    The forked-line method generates genotypes and corresponding probabilities for Mendelian genetic crosses.  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 10. 

    Mendel’s experiments involved both discrete and continuous genetic traits.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 11. 

    The genotype is the physical appearance of a trait.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 12. 

    Normal recessive genes typically do not produce functional products.  

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
  • 13. 

    A testcross can be used to determine whether an individual is homozygous or heterozygous.  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 14. 

    The probability of a woman giving birth to three girls in a row is 1/8.  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 15. 

    The chi-square test is used to determine if observed outcomes are consistent with expected outcomes.  

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
  • 16. 

    Honey bees have a haplo-diploid sex determination system where femalesdevelop from a fertilized egg (they are diploid, having one allele from the femalequeen and 1 allele from the male) and males develop from unfertilized eggs (theyare haploid, having only 1 allele from the queen). What is the probability that a daughter will inherit a particular allele from her mother? What is the probability that a son will inherit a particular allele from his mother?  

    • A.

      The probability that a daughter will inherit a particular allele from her mother is 50%; the probability that a son will inherit a particular allele from his mother is 100%

    • B.

      The probability that a daughter will inherit a particular allele from her mother is 100%; the probability that a son will inherit a particular allele from his mother is 50%

    • C.

      The probability that a daughter will inherit a particular allele from her mother is 50%; the probability that a son will inherit a particular allele from his mother is 50%

    • D.

      None of the above

    Correct Answer
    A. The probability that a daughter will inherit a particular allele from her mother is 50%; the probability that a son will inherit a particular allele from his mother is 100%
  • 17. 

    What is a backcross and a testcross?  

    • A.

      A testcross is used to determine genotypes of individuals that may be heterozygous or homozygous for a dominant allele (and therefore express identical phenotypes). The unknown genotypes are exposed by crossing to a “tester” that is known to be homozygous for the recessive allele in question.

    • B.

      A testcross is used to determine phenotypes of individuals that may be heterozygous or homozygous for a recessive allele (and therefore express identical phenotypes). The unknown genotypes are exposed by crossing to a “tester” that is known to be heterozygous for the dominant allele in question.

    • C.

      A backcross is the mating of F1 progeny back to one of their parents. Backcrosses can also be testcrosses if the original parent is homozygous for the recessive allele(s). Backcrosses are typically used to introgress allele(s) of interest, which segregated out in the F1 progeny, back into the genetic background of one of the original parents.

    • D.

      A backcross is the mating of F2 progeny back to one of their siblings. Backcrosses can also be testcrosses if the original parent is homozygous for the recessive allele(s). Backcrosses are typically used to introgress allele(s) of interest, which segregated out in the F2 progeny, back into the genetic background of one of the original parents.

    Correct Answer(s)
    A. A testcross is used to determine genotypes of individuals that may be heterozygous or homozygous for a dominant allele (and therefore express identical phenotypes). The unknown genotypes are exposed by crossing to a “tester” that is known to be homozygous for the recessive allele in question.
    C. A backcross is the mating of F1 progeny back to one of their parents. Backcrosses can also be testcrosses if the original parent is homozygous for the recessive allele(s). Backcrosses are typically used to introgress allele(s) of interest, which segregated out in the F1 progeny, back into the genetic background of one of the original parents.
  • 18. 

    A man has either an AaBB or AABb genotype with equal probability. a. Assume these genes are unlinked (i.e., assorting independently). What is the overall probability that the man will produce an Ab gamete?  

    • A.

      Only the AABb genotype can produce Ab gametes, and the expected probability of Ab gametes produced will be 1/2. Because the parent has an equal probability (50%) of having either genotype (AaBB or AABb), the final probability of the parent producing an Ab gamete is (1/2) × (1/2) = 1/4 = 0.25 = 25%.

    • B.

      Only the AABb genotype can produce Ab gametes, and the expected probability of Ab gametes produced will be 1/4. Because the parent has an equal probability (50%) of having either genotype (AaBB or AABb), the final probability of the parent producing an Ab gamete is (1/4) × (1/4) = 1/2 = 0.50 = 50%.

    • C.

      Neither of the above

    • D.

      All of the above

    Correct Answer
    A. Only the AABb genotype can produce Ab gametes, and the expected probability of Ab gametes produced will be 1/2. Because the parent has an equal probability (50%) of having either genotype (AaBB or AABb), the final probability of the parent producing an Ab gamete is (1/2) × (1/2) = 1/4 = 0.25 = 25%.
  • 19. 

    A man has either an AaBB or AABb genotype with equal probability. a.  What is the probability of the man producing an AB gamete?  

    • A.

      For genotype AaBB, the probability of generating an AB gamete is 1/2. For genotype AABb, the probability of generating an AB gamete is 1/2. Again, because both genotypes have equal probabilities, the final probability of the parent generating an AB gamete is (1/2) × (1/2) + (1/2) × (1/2) = 2/4 = 0.5 = 50%.

    • B.

      For genotype AaBB, the probability of generating an AB gamete is 1/8. For genotype AABb, the probability of generating an AB gamete is 1/8. Again, because both genotypes have equal probabilities, the final probability of the parent generating an AB gamete is (1/8) × (1/8) + (1/8) × (1/8) = 2/32 = 0.031 = 3%.

    • C.

      Neither of them

    • D.

      All of the above

    Correct Answer
    A. For genotype AaBB, the probability of generating an AB gamete is 1/2. For genotype AABb, the probability of generating an AB gamete is 1/2. Again, because both genotypes have equal probabilities, the final probability of the parent generating an AB gamete is (1/2) × (1/2) + (1/2) × (1/2) = 2/4 = 0.5 = 50%.
  • 20. 

    While doing field work in Madagascar, you discover a new dragonfly species that has either red (R) or clear (r) wings. Initial crosses indicate that R is dominant to r. You perform three crosses using three different sets of redwinged parents with unknown genotype and observe the following data: Cross Phenotypes 1 72 red-winged, 24 clear-winged 2 4 red-winged 3 96 red-winged a. What is the most likely genotype for each pair of parents?  

    • A.

      Cross 1 results in a 3:1 ratio of red-winged to clear-winged progeny, therefore the parents are most likely both Rr. Crosses 2 and 3 result in only red-winged progeny, therefore the parents are most likely all RR.

    • B.

      Cross 1 results in a 2:1 ratio of red-winged to clear-winged progeny, therefore the parents are most likely both Rr. Crosses 2 and 3 result in only red-winged progeny, therefore the parents are most likely all rr.

    • C.

      Neither

    • D.

      All of the above

    Correct Answer
    A. Cross 1 results in a 3:1 ratio of red-winged to clear-winged progeny, therefore the parents are most likely both Rr. Crosses 2 and 3 result in only red-winged progeny, therefore the parents are most likely all RR.
  • 21. 

    While doing field work in Madagascar, you discover a new dragonfly species that has either red (R) or clear (r) wings. Initial crosses indicate that R is dominant to r. You perform three crosses using three different sets of redwinged parents with unknown genotype and observe the following data: Cross Phenotypes 1 72 red-winged, 24 clear-winged 2 4 red-winged 3 96 red-winged Do you think there are a sufficient number of progeny to support each of your answers in the previous question?  

    • A.

      Crosses 1 and 3 have a insufficient number of progeny, but the high number of progeny from cross 3 precludes making any conclusions.

    • B.

      Crosses 1 and 3 have a sufficient number of progeny, but the low number of progeny from cross 2 precludes making any conclusions.

    • C.

      Neither

    • D.

      All of the above

    Correct Answer
    B. Crosses 1 and 3 have a sufficient number of progeny, but the low number of progeny from cross 2 precludes making any conclusions.
  • 22. 

    A cross produces an F1 ratio of 159:41. What is the probability that this reflects a chance departure from a 13:3 expected ratio?  

    • A.

      First, calculate the observed and expected numbers of progeny in the two categories. A 13:3 ratio is equivalent to an 0.8125 probability of having the larger class and a 0.1875 probability of being in the less frequent class. The total individuals are 200, so to calculate the expected number, multiply 0.8125 by 200 and 0.1875 by 200 to yield 162.5 and 37.5. Using the formula for the chi-square goodness-of-fit test, you should obtain a value of 0.402. By checking that value with a single degree of freedom on the chi-square table, you will see that the value is well below the significance threshold. (For your information, the probability is 0.526.) Therefore, we cannot conclude that there is a significant difference between the 13:3 ratio and the 159:41 ratio.

    • B.

      Not listed

    Correct Answer
    A. First, calculate the observed and expected numbers of progeny in the two categories. A 13:3 ratio is equivalent to an 0.8125 probability of having the larger class and a 0.1875 probability of being in the less frequent class. The total individuals are 200, so to calculate the expected number, multiply 0.8125 by 200 and 0.1875 by 200 to yield 162.5 and 37.5. Using the formula for the chi-square goodness-of-fit test, you should obtain a value of 0.402. By checking that value with a single degree of freedom on the chi-square table, you will see that the value is well below the significance threshold. (For your information, the probability is 0.526.) Therefore, we cannot conclude that there is a significant difference between the 13:3 ratio and the 159:41 ratio.
  • 23. 

    Compare and contrast Mendel’s principle of segregation and the principle of independent assortment.  

    • A.

      The principle of segregation involves segregation (separation) of the single alleles of any gene pair as paired homologs separate during meiotic anaphase I. This principle can be demonstrated using a single pair of homologous chromosomes.

    • B.

      The principle of independent assortment involves the random assortment of alleles from different homologs into separate daughter cells during meiosis. This principle can only be demonstrated using two or more pairs of homologous chromosomes.

    • C.

      Not listed

    Correct Answer(s)
    A. The principle of segregation involves segregation (separation) of the single alleles of any gene pair as paired homologs separate during meiotic anaphase I. This principle can be demonstrated using a single pair of homologous chromosomes.
    B. The principle of independent assortment involves the random assortment of alleles from different homologs into separate daughter cells during meiosis. This principle can only be demonstrated using two or more pairs of homologous chromosomes.
  • 24. 

    Two pea plants with purple flowers are crossed. Among the offspring, 63 have purple flowers, and 17 have white flowers. With a chi-square test, compare the observed numbers with a 3:1 ratio and determine the probability that the difference between observed and expected could be a result of chance.  

    • A.

      Plugging the numbers into the chi-square equation: (63 – 60)2/60 + (17 – 20)2 /20 = 0.15 + 0.45 = 0.6 (the chi-square statistic). Degrees of freedom = the number of classes (phenotypes) – 1 = 2 – 1 = 1. Looking at the chisquare table for one degree of freedom and using the standard critical value of 5%, we do not reject the hypothesis and thus conclude that the differences between observed and expected progeny numbers are a result of chance. We can further conclude that both purple parents are heterozygous at the single gene locus controlling flower color (at least for purple and white).

    • B.

      Not listed

    Correct Answer
    A. Plugging the numbers into the chi-square equation: (63 – 60)2/60 + (17 – 20)2 /20 = 0.15 + 0.45 = 0.6 (the chi-square statistic). Degrees of freedom = the number of classes (phenotypes) – 1 = 2 – 1 = 1. Looking at the chisquare table for one degree of freedom and using the standard critical value of 5%, we do not reject the hypothesis and thus conclude that the differences between observed and expected progeny numbers are a result of chance. We can further conclude that both purple parents are heterozygous at the single gene locus controlling flower color (at least for purple and white).
  • 25. 

    How did Sutton’s chromosome theory of inheritance link Mendel’s work with a more mechanistic understanding of heredity.  

    • A.

      Sutton documented the fact that each homologous pair of chromosomes consists of one maternal chromosome and one paternal chromosome. Showing that these pairs segregate independently into gametes in meiosis, he concluded that this process is the biological basis for Mendel’s principles of heredity.

    • B.

      Not listed

    Correct Answer
    A. Sutton documented the fact that each homologous pair of chromosomes consists of one maternal chromosome and one paternal chromosome. Showing that these pairs segregate independently into gametes in meiosis, he concluded that this process is the biological basis for Mendel’s principles of heredity.
  • 26. 

    A couple has one girl and is expecting a second child. What is the probability that this child will be a boy? After several years and several births, this couple now has six daughters and is expecting a seventh. What is the probability that this child will be a boy?  

    • A.

      Like flipping a fair coin, each birth is independent, so in both cases the probability is ½.

    • B.

      1/2 x 1/2 = 1/4

    • C.

      Not listed

    Correct Answer
    A. Like flipping a fair coin, each birth is independent, so in both cases the probability is ½.
  • 27. 

    What conclusions did Mendel make from his monohybrid crosses?  

    • A.

      Progeny inherit genetic factors from both parents.

    • B.

      Each individual possesses two factors (alleles) that control the appearance of each phenotypic trait.

    • C.

      Individual possesses X from dad and Y from mom.

    • D.

      The two alleles in each individual separate (segregate) during gametogenesis and are randomly distributed with equal probability of being distributed into the gametes.

    • E.

      From a cross between two true-breeding (homozygous) parents expressing different phenotypes for a given trait, traits that appeared unchanged in the F1 heterozygous offspring were dominant, and traits that disappeared in F1 heterozygous offspring were recessive.

    Correct Answer(s)
    A. Progeny inherit genetic factors from both parents.
    B. Each individual possesses two factors (alleles) that control the appearance of each phenotypic trait.
    D. The two alleles in each individual separate (segregate) during gametogenesis and are randomly distributed with equal probability of being distributed into the gametes.
    E. From a cross between two true-breeding (homozygous) parents expressing different phenotypes for a given trait, traits that appeared unchanged in the F1 heterozygous offspring were dominant, and traits that disappeared in F1 heterozygous offspring were recessive.
  • 28. 

    Genes come in different versions called:  

    • A.

      Alleles

    • B.

      Loci

    • C.

      Genotypes

    • D.

      Chromosomes

    • E.

      Genomes

    Correct Answer
    A. Alleles
  • 29. 

    Codominant alleles are expressed in individuals that are _____________.  

    • A.

      Penetrant

    • B.

      Homozygous

    • C.

      Polymorphic

    • D.

      Heterozygous

    • E.

      Mutually exclusive

    Correct Answer
    D. Heterozygous
  • 30. 

    The occurrence of partial expressivity and incomplete penetrance demonstrates that gene expression can be influenced by biological or environmental context. Explain this statement and give examples to support it.  

    • A.

      Individuals with identical genotypes can exhibit different degrees of given phenotypes based on their sex, stress levels, lifestyle, nutritional status, and so forth. An individual’s genotype defines genetic potential; the expression of genetic potential can vary greatly depending on other factors that determine the overall context of gene expression. For example, men and women with the same genotype for pattern baldness exhibit very different phenotypes due to the biological context (i.e., male or female) in which the genotype exists in. The high relative level of testosterone produced in men provides a biological context whereby the genotype for baldness can be more fully expressed. The variation in the degree of pattern baldness in men and women with identical “baldness” genotypes is an example of partial expressivity. Note also that stress, nutritional deficiency, and so forth, can also result in loss of hair even in individuals not having a “baldness” genotype.

    • B.

      Not listed

    Correct Answer
    A. Individuals with identical genotypes can exhibit different degrees of given phenotypes based on their sex, stress levels, lifestyle, nutritional status, and so forth. An individual’s genotype defines genetic potential; the expression of genetic potential can vary greatly depending on other factors that determine the overall context of gene expression. For example, men and women with the same genotype for pattern baldness exhibit very different phenotypes due to the biological context (i.e., male or female) in which the genotype exists in. The high relative level of testosterone produced in men provides a biological context whereby the genotype for baldness can be more fully expressed. The variation in the degree of pattern baldness in men and women with identical “baldness” genotypes is an example of partial expressivity. Note also that stress, nutritional deficiency, and so forth, can also result in loss of hair even in individuals not having a “baldness” genotype.
  • 31. 

    Describe the differences between dominance, co-dominance, and incomplete dominance.  

    • A.

      Dominance is the condition in which one allele of a gene pair completely masks or inhibits phenotypic expression of the other allele.

    • B.

      Dominance is the condition in which the complete expression of both alleles of a given gene pair is observed; that is, the expression of neither allele influences the expression of the other.

    • C.

      Co-dominance is the condition in which the complete expression of both alleles of a given gene pair is observed; that is, the expression of neither allele influences the expression of the other.

    • D.

      Dominance is the condition in which one allele only partially inhibits the expression of the other allele in the phenotype. Heterozygotes exhibit phenotypes representing a combination (or blending) of the two homozygotes.

    • E.

      Incomplete (or partial) dominance is the condition in which one allele only partially inhibits the expression of the other allele in the phenotype. Heterozygotes exhibit phenotypes representing a combination (or blending) of the two homozygotes.

    Correct Answer(s)
    A. Dominance is the condition in which one allele of a gene pair completely masks or inhibits phenotypic expression of the other allele.
    C. Co-dominance is the condition in which the complete expression of both alleles of a given gene pair is observed; that is, the expression of neither allele influences the expression of the other.
    E. Incomplete (or partial) dominance is the condition in which one allele only partially inhibits the expression of the other allele in the phenotype. Heterozygotes exhibit phenotypes representing a combination (or blending) of the two homozygotes.

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  • Feb 18, 2013
    Quiz Edited by
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