What is the site of pathology for the following patient?
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A 32-year-old develops polyuria. Her nephrologist monitors her closely on a water deprivation test, and she continues to have increased urine output. A diagnosis of diabetes insipidus is made. The nephrologist orders an antidiuretic hormone level and determines that it is inappropriately elevated.
A. Adenohypophysis B. D1 C. Pituitary function D. V1 E. V2
Adenohypophysis-the correct answer is a. the adenohypophysis is not related to the pathology of diabetes insipidus.answer b is incorrect. d1 receptors are not involved in nephrogenic diabetes insipidus.answer c is incorrect. this is nephrogenic, not central, diabetes insipidus.answer d is incorrect. the v1 receptor is involved in vascular smooth muscle contraction.answer e is incorrect. this scenario describes nephrogenic diabetes insipidus, which is pathology at the antidiuretic hormone receptor in the kidney. this receptor is the v2 receptor.