What is the best way to differentiate B cells from T cells? - ProProfs
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What is the best way to differentiate B cells from T cells?




This question is part of REVIEW IN CLINICAL IMMUNOLOGY & SEROLOGY
Asked by Mmtech_ on Apr 14, 2017

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4 Answers

C. Evins

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C. Evins
College Student, Schooling, Wolverhampton

Answered on Oct 03, 2019

There are so many ways to differentiate B cells from T cells. Below are some notable differences: B cells are produced in the bone marrow, and they also mature in the Bone marrow. These cells produce and secrete antibodies. Antibodies fight against pathogens that have gotten into the body. There are two types of B cells: the memory cells and plasma cells.

B cells have a B cell receptor, also known as BCR. T cells are also produced in the bone marrow, but they travel to the thymus where they mature. T cells identify viruses and microorganisms by the antigen-presenting cells (APC) present on the surface of the cell. There are two types of T cells: cytotoxic T cells and helper T cells. T cells have T cell receptor commonly referred to as TCR. Compared to B cells, T cells have a longer life span. I hope you find this information helpful.

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safoora

Safoora

Answered on Apr 25, 2018

T cells mature in the thymus and B cells mature in the bone marrow. T cells are involved in T cell mediated immunity where they do not produce any antibodies. On the other hand, B cells are involved in humoral antibodies and are responsible to produce antibodies specific to the antigens.B cells have receptors i.e IgM serves as a receptor for antigen. T cells have receptors(TCR) for antigen presenting cells in contrast to certain MHC which is I and II.

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Nibras Saleam Al-Ammar

Nibras Saleam Al-Ammar

Answered on Oct 11, 2017

I used a method in my Master research to differentiate T cells from B cells by rossate formation with sheep RBCs.

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John Adney

John Adney

Answered on May 21, 2017

B cells recognize certain antigens (through B cell receptor) and mature and develop into specialized forms that produce any of the five classes of immhuoglobulins capable of rapid & efficient neutralization of antigens.
T cells also recognize certain antigens (through T cell receptor) in association with certain molecules and respond to antigens by releasing chemical substances that promote protective biological processes.T cells also over help to B cells.
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