What is the difference between Okazaki Fragments and Lagging Strand? - ProProfs Discuss
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What is the difference between Okazaki Fragments and Lagging Strand?

Asked by S. Barnes, Last updated: Sep 11, 2019

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4 Answers

N. Reyes

A good writer and orator as well.

N. ReyesWriter, B.ed, California
Writer, B.ed, California

Answered on Oct 22, 2019

If you are studying chemistry, Okazaki Fragments and lagging strands are known to be common terms that are used. They are part of the DNA replication process. Okazaki fragments usually occur during DNA replication. They are the fragments that will start forming on the lagging strand. The lagging strand is the DNA strand that will replicate in a certain direction.

These two are different from each other, but they also complement each other. They usually appear in eukaryotes that come with more complicated cell structures as compared to the usual cells. Aside from the lagging strand, there is also another strand needed to complete the whole process called the leading strand.

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H. Jones

H. JonesWeb Content Writer, San Antonio,
Web Content Writer, San Antonio,

Answered on Sep 11, 2019

Okazaki fragments and lagging strands are terms in DNA replication. These two terms are not in any way the same, but they are related. Lagging strands refers to the DNA strands that grow or replicate in a discontinuous manner. It becomes by producing Okazaki fragments. For Okazaki fragments to be added to the lagging strand, a new primer is needed for each Okazaki fragment. These primers are later removed by DNA polymerase I and the gaps between the Okazaki fragments are sealed off by DNA ligase.

Okazaki fragments are small fragments of DNA added to the lagging strands. It was named after the Japanese scientist that discovered it. The leading strand of DNA does not have Okazaki fragments as it grows in a continuous manner rather than a discontinuous manner like the lagging strand. In summary, the lagging strand is the DNA strand that grows in a discontinuous manner, and Okazaki fragments are fragments added to the lagging strand. I hope this helps.

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F. Ray

F. RayStudent, Kansas City
Student, Kansas City

Answered on Sep 06, 2019

These are two terms that are familiar to those who are taking up chemistry. These are both used during the DNA replication process. One of the main differences between the two is their size. Okazaki fragments are known to be short. These short strands are the end products of the new DNA fragments that have formed on the lagging strand.

The lagging strand is a type of DNA fragment that can be replicated discontinuously. It was in the year 1966 when Reiji Okazaki and Kiwako Sakabe first discovered the Okazaki fragments. It is easy to see how the fragment has gotten its name.

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J. Pollock

J. PollockScience Professor, Los Angeles
Science Professor, Los Angeles

Answered on Sep 04, 2019

There are some people who are familiar with Ozakaki Fragments and Lagging Strand because these are terms that are normally used for chemistry. These two are actually complementary with each other. These two are used in the DNA replication process. One of the things that will set the Ozakaki fragments from the Lagging Strand is their length.

The lagging strand is also replicated discontinuously from a certain direction. If in case you are wondering where these fragments have gotten their names, they were discovered by Kiwako Sakabe and Reiji Okazaki. They were the ones who came up with the names.

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