Demonstrate a sound knowledge of the principles of transcription Demonstrate an appreciation of RNA processing in the nucleus, including intron removal and differential splicing
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True
False
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It is more reactive than DNA
It is less reactive than DNA
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5' to 3'
3' to 5'
N to C
C to N
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The 3′ end of the mRNA gets a tail of poly-A nucleotides
The 5' end of the mRNA gets a tail of poly-A nucleotides
The 3′ end of the mRNA gets a tail of poly-B nucleotides
The 5′ end of the mRNA gets a tail of poly-B nucleotides
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Its sugar, ribose, has a 2' OH group
Its sugar, ribose, has a 4' OH group
RNA base uracil is more chemically reactive than DNA base thymine
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3' to 5'
5' to 3'
C to N
N to C
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Small nuclear RNAs (snRNAs)
Transfer RNAs (tRNAs)
Small interfering RNAs (siRNAs)
Micro RNAs (miRNAs)
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The 5' end is "capped" with an atypical nucleotide.
The 3' end is "capped" with an atypical nucleotide.
The 5' end is "capped" with a typical nucleotide.
The 3' end is "capped" with a typical nucleotide.
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Pyrophosphate is lost from NTP, and breakage of phosphoanhydride bond provides energy for polymerisation
A phosphate is lost from NTP, and breakage of phosphoanhydride bond provides energy for polymerisation
Pyrophosphate is lost from NTP, and breakage of hydrogen bond provides energy for polymerisation
A phosphate is lost from NTP, and breakage of hydrogen bond provides energy for polymerisation
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Single stranded, so no back-up of genetic information
More prone to mutate; cytosine --> uracil cannot be detected and repaired
More prone to mutate; adenine --> uracil cannot be detected and repaired
Double stranded, so mutation twice as likely
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