Pedigree Quiz: Test Your Knowledge About The Pedigree Diagram

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Questions: 28 | Attempts: 29,954 | Updated: Feb 21, 2024

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Pedigree Quiz: Test Your Knowledge About The Pedigree Diagram - Quiz

Think you are a Biology buff? Do you want to test your genetic knowledge? This quiz is based on the pedigree diagram that represents biological relationships between an organism and its ancestors. Ever wondered how much you know about the pedigree diagram. Let's play this quiz and prove yourself!

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Current Version
Feb 21, 2024

Quiz Edited by
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Dec 05, 2011

Quiz Created by
BLACKMD

Pedigree Quiz: Test Your Knowledge About The Pedigree Diagram

II-3 in the pedigree below has two brothers with hemophilia A, a bleeding disorder that is inherited as an X‑linked recessive trait. What is the risk of hemophilia for her children?

II-3 in the below family has two brothers and three sons with classical hemophilia (factor VIII deficiency). Now she is pregnant again. How likely is it that this child will also have hemophilia?

II-3 in the below family has two brothers with hemophilia and three healthy sons. How likely is it that she is a carrier of the hemophilia gene?

In the below family, a child has been born with Acheiropodia (congenital absence of hands and feet). Assuming that this is a genetic problem, what is the MOST LIKELY inheritance pattern and how LIKELY is it that a next child of III3 and III4 will be affected?

Given that the onset of the disease is by 40 years of age and given that all of the individuals shown are at least 45-years-old except III‑2 who is only 30-years-old, what is the probability that the fetus (IV-1) will be affected?

In the family below, two brothers have classical hemophilia. Now I-4 asks you about the risk that her children will have hemophilia. You can tell her that the risk is:

It turns out that after two healthy sons, the third son of I-4 in the family above has hemophilia. After this sad event, what is the chance that a next child will be affected?

Now assume that I-4 (above) has two healthy sons. In that case, you can use Bayes' theorem to figure out that her chance of being a carrier is:

Albinism is a harmless autosomal recessive trait. If we assume that 2% of the general population are carriers of the albinism gene, how likely is it that the child of an albino with a healthy unrelated partner is an albino?

Now assume that the unaffected sister of an albino asks you how likely it is that her child with a healthy unrelated man will be an albino. Her parents are both unaffected. Assume again a carrier frequency of 2% in the general population.

The pedigree below represents a family with cystic fibrosis (autosomal recessive). What is the risk that individual II‑2 will have an affected child if the prevalence of cystic fibrosis is 1 in 2500 individuals?

The figure below shows the pedigree of a family with Huntington disease. Which of the following statements best describes the linkage analysis for the person indicated by the arrow (III‑2)?

A normal male mates with a female who is homozygous for an x‑linked recessive disorder. Of the offspring that they may have, it is probable that:

What is the probability of having an affected child if one parent is affected with an autosomal recessive disease and the other parent is unaffected?

Parents of a child with an autosomal recessive disease are:

If one parent has an autosomal dominant disorder and is a heterozygote, what are the chances that they will have an affected offspring?

What is the probability that an offspring of an affected person and an unaffected person with an autosomal dominant disorder will be affected?

What proportion of all offspring are affected females if the father is affected with an X‑linked recessive disease and the mother is a carrier of the same disease?

If an affected male mates with a normal female and has four offspring: one normal male, one affected male, and two affected female, the disease is MOST LIKELY inherited as:

If your mother was known to be a carrier of alpha‑antitrypsin deficiency, an autosomal recessive disorder, what is the probability that your child is also a carrier of this disease gene?

A normal male mates with a female who is a carrier for an x‑linked recessive disorder. Of the offspring that they may have, it is probable that:

What is the probability of having an affected child if one parent is affected with an autosomal recessive disease and the other parent is a carrier?

If an affected male mate with a phenotypically normal female and has both an affected male and an affected female offspring, the disease is MOST LIKELY inherited as:

Pedigree Quiz: Test Your Knowledge About The Pedigree Diagram

II-3 in the pedigree below has two brothers with hemophilia A, a bleeding disorder that is inherited as an X‑linked recessive trait. What is the risk of hemophilia for her children?

II-3 in the below family has two brothers and three sons with classical hemophilia (factor VIII deficiency). Now she is pregnant again. How likely is it that this child will also have hemophilia?

II-3 in the below family has two brothers with hemophilia and three healthy sons. How likely is it that she is a carrier of the hemophilia gene?

In the below family, a child has been born with Acheiropodia (congenital absence of hands and feet). Assuming that this is a genetic problem, what is the MOST LIKELY inheritance pattern and how LIKELY is it that a next child of III3 and III4 will be affected?

Given that the onset of the disease is by 40 years of age and given that all of the individuals shown are at least 45-years-old except III‑2 who is only 30-years-old, what is the probability that the fetus (IV­-1) will be affected?

In the family below, two brothers have classical hemophilia. Now I-4 asks you about the risk that her children will have hemophilia. You can tell her that the risk is:

It turns out that after two healthy sons, the third son of I-4 in the family above has hemophilia. After this sad event, what is the chance that a next child will be affected?

Now assume that I-4 (above) has two healthy sons. In that case, you can use Bayes' theorem to figure out that her chance of being a carrier is:

Albinism is a harmless autosomal recessive trait. If we assume that 2% of the general population are carriers of the albinism gene, how likely is it that the child of an albino with a healthy unrelated partner is an albino?

Now assume that the unaffected sister of an albino asks you how likely it is that her child with a healthy unrelated man will be an albino. Her parents are both unaffected. Assume again a carrier frequency of 2% in the general population.

The pedigree below represents a family with cystic fibrosis (autosomal recessive). What is the risk that individual II‑2 will have an affected child if the prevalence of cystic fibrosis is 1 in 2500 individuals?

The figure below shows the pedigree of a family with Huntington disease. Which of the following statements best describes the linkage analysis for the person indicated by the arrow (III‑2)?

A normal male mates with a female who is homozygous for an x‑linked recessive disorder. Of the offspring that they may have, it is probable that:

What is the probability of having an affected child if one parent is affected with an autosomal recessive disease and the other parent is unaffected?

Parents of a child with an autosomal recessive disease are:

If one parent has an autosomal dominant disorder and is a heterozygote, what are the chances that they will have an affected offspring?

What is the probability that an offspring of an affected person and an unaffected person with an autosomal dominant disorder will be affected?

What proportion of all offspring are affected females if the father is affected with an X‑linked recessive disease and the mother is a carrier of the same disease?

If an affected male mates with a normal female and has four offspring: one normal male, one affected male, and two affected female, the disease is MOST LIKELY inherited as:

If your mother was known to be a carrier of alpha‑antitrypsin deficiency, an autosomal recessive disorder, what is the probability that your child is also a carrier of this disease gene?

A normal male mates with a female who is a carrier for an x‑linked recessive disorder. Of the offspring that they may have, it is probable that:

What is the probability of having an affected child if one parent is affected with an autosomal recessive disease and the other parent is a carrier?

If an affected male mate with a phenotypically normal female and has both an affected male and an affected female offspring, the disease is MOST LIKELY inherited as:

Given that the onset of the disease is by 40 years of age and given that all of the individuals shown are at least 45-years-old except III‑2 who is only 30-years-old, what is the probability that the fetus (IV-1) will be affected?