A Review Quiz On Pharmacology

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Bronchiectasis is a condition characterized by the widening and inflammation of the bronchial tubes in the lungs. This can lead to a buildup of mucus and bacteria, causing recurrent infections and difficulty breathing. Beta-2 adrenergic agonists are a type of medication that can help to relax and open up the airways, making it easier to breathe. Therefore, the correct answer is "Beta-2 adrenergic agonist therapies."

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Beta1 and Beta2 are mentioned as antiarrhythmic agents, which means they have the ability to stabilize irregular heart rhythms. This suggests that they can increase the efficiency of atrioventricular block by restoring normal heart rhythm.

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Adrenaline stimulates alpha1-adrenoceptors, which causes vasoconstriction of blood vessels. This leads to an increase in blood pressure.

Bronchial smooth muscle contraction is inhibited by beta2-adrenergic receptor stimulation. This means that when beta2-adrenergic receptors are activated, they prevent the contraction of the bronchial smooth muscles. This is important in the context of asthma, as bronchial smooth muscle contraction leads to airway constriction and narrowing, making it difficult for air to pass through the airways. By inhibiting this contraction, beta2-adrenergic receptor stimulation helps to relax the airways and improve airflow, providing relief for asthmatic symptoms.

The correct answer is "გუგების გაფართოება" (increased heart rate). Adrenaline stimulates the alpha-adrenergic receptors in the heart, causing the heart rate to increase. This is a physiological response that prepares the body for a fight-or-flight response in stressful or dangerous situations.

Bronchial smooth muscle contraction is mediated by beta2-adrenergic receptors. Beta1-adrenergic receptors are not involved in bronchial smooth muscle contraction. Adrenaline, released by the adrenal medulla, acts on beta2-adrenergic receptors to relax bronchial smooth muscle. Norepinephrine, released from sympathetic nerve endings, acts on alpha-adrenergic receptors to contract bronchial smooth muscle. Therefore, the correct answer is that bronchial smooth muscle contraction is mediated by beta2-adrenergic receptors.

The effects of adrenaline that are connected to beta2-adrenoceptors include bronchodilation, which means the relaxation and widening of the bronchial tubes. This allows for increased airflow and improved breathing.

Ephedrine is a sympathomimetic drug that stimulates both the heart's systolic contraction and overall peripheral vasoconstriction, leading to an increase in blood pressure. Phenotol, salbutamol, and isoprotenerol are not known to have these effects.

The correct answer is "ნორადრენალინი" because it is the only option that is a type of hormone. Noradrenaline, also known as norepinephrine, is a hormone and neurotransmitter that is released by the adrenal glands in response to stress. The other options, dobutamine, fenoterol, and salmeterol, are medications used for various purposes but are not hormones.

The correct answer is "ბეტა1, ბეტა2-ადრენომიმეტური საშუალებები." This means that beta-1 and beta-2 adrenergic receptors are stimulated, which increases the strength of the heart muscle contraction and the frequency of heart contractions. This leads to increased cardiac output.

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Ephedrine is a sympathomimetic drug that stimulates the release of norepinephrine from nerve endings, thereby increasing its availability. This enhances the overall sympathetic nervous system activity, leading to various physiological effects such as increased heart rate, blood pressure, and bronchodilation.

The correct answer is "ეფედრინი" because it is a well-known and commonly used non-selective sympathomimetic drug. It acts on both alpha and beta adrenergic receptors, causing vasoconstriction and bronchodilation. It is commonly used as a nasal decongestant and bronchodilator in conditions such as asthma and allergies. Adrenaline (ადრენალინი), xylometazoline (ქსილომეტაზოლინი), and salbutamol (სალბუტამოლი) are also sympathomimetic drugs, but they have more selective actions and different clinical uses.

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The correct answer is "იზოპროტერენოლი" because it is the only option that is not a type of adrenaline. The other options, "ეფედრინი," "ნორადრენალინი," and "ადრენალინი," are all different forms of adrenaline.

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The given options are describing the division of noradrenaline, a neurotransmitter, based on its characteristics. The term "პოსტგანგლიური" refers to postganglionic, which means it is released after the ganglion in the autonomic nervous system. "სიმპათიკური" means sympathetic, which is one of the divisions of the autonomic nervous system responsible for the fight-or-flight response. Therefore, the correct answer is "პოსტგანგლიური სიმპათიკური ბოჭკოებით," which means postganglionic sympathetic.

The effects of adrenaline that are not mediated by beta-adrenoceptors include the dilation of blood vessels in the eyes.

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The correct answer is "ალფა1-ადრენომიმეტური საშუალებები" because the sentence states that "they increase the level of adrenaline in the blood." This indicates that the drugs mentioned in the options are alpha-1 adrenergic agonists, which stimulate the release of adrenaline.

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Beta-1 and beta-2 adrenergic receptors are responsible for vasoconstriction, which means they constrict the blood vessels. This leads to an increase in blood pressure. Therefore, blocking these receptors would prevent vasoconstriction and lower blood pressure.

The correct answer is "პოსტსინაფსური და არასინაფსური ადრენორეცეპტორების პირდაპირი სტიმულაცია". This answer suggests that the main mechanisms of action for adrenergic drugs are the direct stimulation of both post-synaptic and non-synaptic adrenoceptors. This means that these drugs directly interact with and activate adrenoceptors in order to produce their effects.

Endogenous adrenaline activates alpha2-adrenoceptors, which leads to vasoconstriction, inhibition of noradrenaline release from adrenergic nerves, tachycardia, and bronchial smooth muscle relaxation.

Isoproterenol is a medication that is used to treat bradycardia, which is a slow heart rate. It works by stimulating beta-adrenergic receptors in the heart, causing an increase in heart rate. This medication is commonly used in emergency situations when the heart rate is dangerously low and needs to be increased quickly. Noradrenaline, dobutamine, and phenylephrine are not typically used to treat bradycardia, so they are not the correct answer.