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Chapter 11

14 Questions  I  By RiseAsOne
Chapter 11
DNA: The Molecule of Heredity

  
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1.  What did Wilkins and Franklin discover?
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2.  How can we best summarize the role of Watson and Crick in discovering the structure of DNA?
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3.  What forms the backbone of a DNA molecule?
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4.  Look at the structures of adenine and cytosine. Why can't adenine bind to cytosine like it binds to thymine?
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5.  What is the complementary strand to the following sequence? ATTGCC
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6.  When sequencing DNA, scientists usually only determine the sequence of one of the two strands. Why is this?
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7.  How is it that the entire diversity of life can be spelled out using only four different bases?
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8.  On the molecular level, what exactly is a mutation?
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10.  Scientists can perform a process called polymerase chain reaction in the lab in order to copy DNA inside a test tube. This method is part of creating a DNA fingerprint of a suspected criminal. Cells from the suspect's cheek are placed into a tube. They are popped open and all the proteins and lipids are removed from the solution. The strands of DNA are separated by heating and polymerase is added to copy the DNA. What necessary component of DNA replication has been left out of this description?
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11.  What is the final result of DNA replication of one chromosome?
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12.  You wish to prove that DNA replication is semi-conservative. You choose to work with bacteria because they only have a single chromosome. You have a very special device that can measure radiation in individual cells. Which radioactive element or compound should you add to the cells prior to division and what do you expect to see?
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13.  How do cigarettes and radiation cause cancer?
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14.  Where in the cell cycle would a checkpoint activate if a mistake were made during replication?
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