3g03 Test 5

25 Questions  I  By ISci2A18
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3G03 Test 5

  
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1.  RNA interference is a mechanism of posttranscriptional RNA-dependent
A.
B.
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D.
E.
2.  ____ is a process essential to maturation of eukaryotic mRNA, and allows for production of multiple proteins from one gene.
A.
B.
C.
D.
E.
3.  Which of the following statements regarding eukaryotic transcription is TRUE?
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B.
C.
D.
E.
4.  Which of the following is NOT one of the six highly conserved proteins that initiate transcription in eukaryotes?
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B.
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D.
E.
5.  Chromatin remodeling may precede transcription. Which of the following is NOT a way that transcriptionally inactive DNA maintains a condensed state?
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B.
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D.
E.
6.  Transcriptionally active DNA in eukaryotes is contained in ____.
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B.
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D.
E.
7.  The expressed sequences of eukaryotic pre-mRNAs are known as ____.
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8.  In eukaryotics, mRNAs are synthesized in the cell ____, whereas most translation occurs in the ____.
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D.
E.
9.  When an activator binds to the enhancer, a protein complex known as Mediator links the enhancer-bound activator to the transcription machinery poised at the ____.
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10.  Prokaryotic mRNA encodes ____.
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11.  Eukaryotic promoter regions can contain canonical sequences, which mark the site of transcription initiation. One such sequence is the TATA box. Transcription in eukaryotes is mediated by the TATA box in the following way:
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E.
12.  Choose the correct statement.
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13.  During transcription, the DNA strands separate, and RNA polymerase constructs an RNA molecule that forms a short hybrid helix with the ____.
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14.  RNA transcription is apparently carried out by immobile protein complexes that reel in the ____.
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D.
E.
15.  Which of the following best describes the functioning of the lac repressor protein?
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E.
16.  The phosphorylation of the CTD of RNA polymerase II is important for which phase of transcription?
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D.
E.
17.  Most  ____ have well defined 3'ends terminating in poly(A) tails of ~250 nucleotides.
A.
B.
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D.
E.
18.  During which of the following processes are RNA-DNA hybrids observed?
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19.  The shift from initiation to elongation in eukaryotes involves structural changes in RNA polymerase, including ____ of its C-terminal domain
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20.  In eukaryotes, the three RNA polymerases recognize
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21.  How does the preinitiation complex begin to form at a TATA box-containing eukaryotic promoter?
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D.
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22.  Which of the following statements best describes the role of sigma factors in bacterial gene expression?
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B.
C.
D.
E.
23.  Which of the following statements is FALSE?
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B.
C.
D.
E.
24.  You are a researcher studying a genetic disease, which results in neurodegeneration through production of an aberrant protein. To understand the impact this protein has within the cell, you decide to perform an experiment to reduce its expression in cells grown in a tissue culture. To do this, you:
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B.
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D.
E.
25.  Which of the following factors mediate(s) splicing?
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B.
C.
D.
E.
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