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3g03 Test 5

25 Questions  I  By ISci2A18
3G03 Test 5

  
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Question Excerpt

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1.  Which of the following statements is FALSE?
A.
B.
C.
D.
E.
2.  Most  ____ have well defined 3'ends terminating in poly(A) tails of ~250 nucleotides.
A.
B.
C.
D.
E.
3.  Choose the correct statement.
A.
B.
C.
D.
E.
4.  RNA transcription is apparently carried out by immobile protein complexes that reel in the ____.
A.
B.
C.
D.
E.
5.  In eukaryotes, the three RNA polymerases recognize
A.
B.
C.
D.
E.
6.  Transcriptionally active DNA in eukaryotes is contained in ____.
A.
B.
C.
D.
E.
7.  Prokaryotic mRNA encodes ____.
A.
B.
C.
D.
E.
8.  Which of the following best describes the functioning of the lac repressor protein?
A.
B.
C.
D.
E.
9.  Eukaryotic promoter regions can contain canonical sequences, which mark the site of transcription initiation. One such sequence is the TATA box. Transcription in eukaryotes is mediated by the TATA box in the following way:
A.
B.
C.
D.
E.
10.  Chromatin remodeling may precede transcription. Which of the following is NOT a way that transcriptionally inactive DNA maintains a condensed state?
A.
B.
C.
D.
E.
11.  RNA interference is a mechanism of posttranscriptional RNA-dependent
A.
B.
C.
D.
E.
12.  Which of the following is NOT one of the six highly conserved proteins that initiate transcription in eukaryotes?
A.
B.
C.
D.
E.
13.  When an activator binds to the enhancer, a protein complex known as Mediator links the enhancer-bound activator to the transcription machinery poised at the ____.
A.
B.
C.
D.
E.
14.  The phosphorylation of the CTD of RNA polymerase II is important for which phase of transcription?
A.
B.
C.
D.
E.
15.  Which of the following statements best describes the role of sigma factors in bacterial gene expression?
A.
B.
C.
D.
E.
16.  During transcription, the DNA strands separate, and RNA polymerase constructs an RNA molecule that forms a short hybrid helix with the ____.
A.
B.
C.
D.
E.
17.  ____ is a process essential to maturation of eukaryotic mRNA, and allows for production of multiple proteins from one gene.
A.
B.
C.
D.
E.
18.  During which of the following processes are RNA-DNA hybrids observed?
A.
B.
C.
D.
E.
19.  You are a researcher studying a genetic disease, which results in neurodegeneration through production of an aberrant protein. To understand the impact this protein has within the cell, you decide to perform an experiment to reduce its expression in cells grown in a tissue culture. To do this, you:
A.
B.
C.
D.
E.
20.  The expressed sequences of eukaryotic pre-mRNAs are known as ____.
A.
B.
C.
D.
E.
21.  Which of the following factors mediate(s) splicing?
A.
B.
C.
D.
E.
22.  How does the preinitiation complex begin to form at a TATA box-containing eukaryotic promoter?
A.
B.
C.
D.
E.
23.  In eukaryotics, mRNAs are synthesized in the cell ____, whereas most translation occurs in the ____.
A.
B.
C.
D.
E.
24.  Which of the following statements regarding eukaryotic transcription is TRUE?
A.
B.
C.
D.
E.
25.  The shift from initiation to elongation in eukaryotes involves structural changes in RNA polymerase, including ____ of its C-terminal domain
A.
B.
C.
D.
E.
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