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NBME Questions and Answers (Q&A)

The correct answer to this question is A. Alcohol dehydrogenase is a group of dehydrogenase enzymes, a class of zinc enzymes, that catalyze the oxidation of primary and secondary alcohols and facilitate the interconversion of alcohols and aldehydes with the reduction of hydride anion to NAD+ to NADH, the realease of a proton.

Alcohol dehydrogenase will be inhibited because it is the first step in the metabolism of both methanol and ethylene glycol. The patient has tachypea which is abnormally rapid breathing. The patient also has anion gap metabolic acidosis which is the result of type I diabetes, chronic alcoholism, or undernutrition.

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Amount of calcium sequestered in the sarcoplasmic reticulum is highestduring relaxation, i.e. when not contracting. Thus it is highest when the stimulus frequency is lowest -> Answer A.

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Dx is Cushing disease based off of the classic sx(adbo stria, wt gain, htn,central obesity) therefore Answer is Cortical Hyperplasia. ACTH-secreting pituitary adenoma (Cushing disease); paraneoplastic ACTH secretion (eg, small cell lung cancer, bronchial carcinoids)—result in ACTH, bilateral adrenal hyperplasia.

You fell for the bait like many of us. Pituitary adenoma can be for any of the "FLAT PiG" hormones. This was specifically ACTH-secreting pituitary adenoma (Cushing disease).

Adrenal hypertrophy may be a result of stress or indeed may result from functional impairment of the adrenal cortex and reduced capacity to secrete glucocorticoids (in turn resulting in diminished negative feedback inhibition of ACTH and overstimulation of the gland

Pt would not have sx of Cushing for a pituitary tumor but rather Sx of which ever "FLAT PiG" hormone is excessivly spewing out ie Prolactinoma -Headache gynacomastia galactorrhea.

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The answer is C. The most appropriate therapy for a female newborn that has been delivered at 34 weeks into the gestation period in an advanced care setting where special delivery systems are available where the diagnosis of persistent pulmonary hypertension has been made is a treatment with nitric oxide.

This is also under the circumstances where the newborn can be carefully monitored for methemoglobinemia. In this question, they were looking for the treatment for pulmonary hypertension and nitric oxide helps to reduce pulmonary hypertension by decreasing the vascular resistance. This is the only choice which fits the situation and provides the appropriate treatment.

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The correct answer to this question is E, Praziquantel. This medication is sold under other brand names, such as Biltricide. It is used to treat many parasitic worm infections, including tapeworm infections, schistosomiasis, opisthorchiasis, and fluke infections. The medication is taken orally and is not recommended for use for worm infections in the eye.

Like all medications, there are side effects that can occur, including headaches, vomiting, and pain in the abdomen. In 1982 was when Praziquantel was first approved for use in the United States and it is regarded as one of the safest and most effective medicines. An average cost of treatment can range from $100 to $200

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