Bch211 - Exam 2

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 Bch211 - Exam 2
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1.  True or false:  Enzymes, being proteins, are sensitive to temperature and will be denatured by high temperatures.
A.
B.
2.  True or false:  Energy is generally consumed during anabolism
A.
B.
3.  True or false:  Aspirin acts as an reversible inhibitor of the COX 2 enzyme
A.
B.
4.  Which of the following is a common function of many vitamins in the body?
A.
B.
C.
D.
5.  The following structure is shown in 
A.
B.
C.
D.
6.  The following represents the results of an experiment on a metabolic enzyme.  What is the optimum pH of this enzyme?
A.
B.
C.
D.
7.  A metal ion required for enzyme activity is called
A.
B.
C.
D.
8.  Sugars which contain an aldehyde group that can be oxidized are called
A.
B.
C.
D.
9.  The cyclic form of glucose results from the formation of
A.
B.
C.
D.
10.  The carbohydrate below may be classified as
A.
B.
C.
D.
11.  The conditions required for maximum enzyme function are called:
A.
B.
C.
D.
12.  The synthesis of an enzyme in response to a cellular need is called
A.
B.
C.
D.
13.  The following compounds are enantiomers of each other
A.
B.
C.
D.
14.  A monosaccharide used to form nucleic acids is
A.
B.
C.
D.
15.  Which of the following terms can be used correctly to fill the blank in the following equation?  
A.
B.
C.
D.
16. 
  1. Lineweaver Burke - If everything else has a higher slope, anything lower than it represents the activation space.  everything above it represents the inhibition space
Gibbs free energy  delta G(negative - ) = spontaneous delta G(positive +) = nonspontaneous
A.
B.
C.
D.
17.  Which form of monosaccharides is preferred by human cells?
A.
B.
C.
D.
18.  Refer to Exhibit 6A.  "Hindrate" is an inhibitor of triose phosphate isomerase.  When it is added to cells at a concentration of 0.1 nM, the enzyme's Km for the substrate is unchanged, but the apparent Vmax is altered to 50nM/sec. 
A.
B.
C.
D.
19.  The structure below is shown in what anomeric form?
A.
B.
C.
D.
20.  A short description of a diastereomer would be?
A.
B.
C.
D.
21.  Which of the following is correctly called a complex carbohydrate?
A.
B.
C.
D.
22.  If an inhibitor changes the slope of the Lineweaver-Burk graph, but not the x-intercept, it is this type of inhibition:
A.
B.
C.
D.
E.
23.  Draw the structure of B-D-Lactose in the Hawarth projection
A.
B.
C.
D.
24.  Which of the following is true of a noncompetitive inhibitor?
A.
B.
C.
D.
25.  Which of the following terms is a general definition of an enzyme?
A.
B.
C.
D.
26.  Structurally, glycogen is most similar to 
A.
B.
C.
D.
27.  Which of the following enzyme properties is explained by the lock-and-key model?
A.
B.
C.
D.
28.  The simplest carbohydrates are called
A.
B.
C.
D.
29.  Under saturation conditions, an enzyme-catalyzed reaction had a velocity V.  Which of the following would increase the rate of the reaction?
A.
B.
C.
D.
30.  The region of an enzyme where the substrate molecule fits is called the
A.
B.
C.
D.
31.  21000 molecules were acted on by a single molecule of an enzyme in 15 minutes.  What is the turnover number?
A.
B.
C.
D.
32.  A Lineweaver-Burk plot is useful in the analysis of enzymatic reactions because
A.
B.
C.
D.
33.  In the induced-fit model of substrate binding to enzymes
A.
B.
C.
D.
34.  Competitive inhibitors have this effect:
A.
B.
C.
D.
E.
35.  The value of Vmax changes in 
A.
B.
C.
D.
36.  What happens to the entropy when ATP is hydrolyzed to ADP?
A.
B.
C.
D.
37.  A polysaccharide containing B(14) linkages is
A.
B.
C.
D.
38.  The structure given below has what type of glycosidic linkage?
A.
B.
C.
D.
39.  Which of the following inhibitors binds to the enzyme at a site other than the active site?
A.
B.
C.
D.
E.
40.  Which statement about enzymes is incorrect?
A.
B.
C.
D.
41.  The sign of Gibb's Free Energy is positive ("+") when energy is released
A.
B.
42.  If the reaction AB has G = +15 Joule/mol and the reaction BC has G = -25 Joule/mol, the overall energy change AC will be  
A.
B.
C.
D.
E.
43.  If the y-intercept of a Lineweaver-Burk plot = 1.91 (sec/millimole) and the slope = 75.3L/sec, Km equals:
A.
B.
C.
D.
E.
44.  Reactions requiring energy often occur with the simultaneous hydrolysis of
A.
B.
C.
D.
45.  Which of the following is a disaccharide?
A.
B.
C.
D.
46.  The theory that proposes a somewhat flexible enzyme conformation is the 
A.
B.
C.
D.
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