Bch211 - Exam 2

46 Questions  I  By Grj2010
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1.  The following structure is shown in 
A.
B.
C.
D.
2.  Which of the following is true of a noncompetitive inhibitor?
A.
B.
C.
D.
3.  Which of the following enzyme properties is explained by the lock-and-key model?
A.
B.
C.
D.
4.  The structure given below has what type of glycosidic linkage?
A.
B.
C.
D.
5.  If the reaction AB has G = +15 Joule/mol and the reaction BC has G = -25 Joule/mol, the overall energy change AC will be  
A.
B.
C.
D.
E.
6. 
  1. Lineweaver Burke - If everything else has a higher slope, anything lower than it represents the activation space.  everything above it represents the inhibition space
Gibbs free energy  delta G(negative - ) = spontaneous delta G(positive +) = nonspontaneous
A.
B.
C.
D.
7.  True or false:  Aspirin acts as an reversible inhibitor of the COX 2 enzyme
A.
B.
8.  Sugars which contain an aldehyde group that can be oxidized are called
A.
B.
C.
D.
9.  Which of the following is a disaccharide?
A.
B.
C.
D.
10.  If the y-intercept of a Lineweaver-Burk plot = 1.91 (sec/millimole) and the slope = 75.3L/sec, Km equals:
A.
B.
C.
D.
E.
11.  A short description of a diastereomer would be?
A.
B.
C.
D.
12.  The simplest carbohydrates are called
A.
B.
C.
D.
13.  A Lineweaver-Burk plot is useful in the analysis of enzymatic reactions because
A.
B.
C.
D.
14.  Under saturation conditions, an enzyme-catalyzed reaction had a velocity V.  Which of the following would increase the rate of the reaction?
A.
B.
C.
D.
15.  The sign of Gibb's Free Energy is positive ("+") when energy is released
A.
B.
16.  21000 molecules were acted on by a single molecule of an enzyme in 15 minutes.  What is the turnover number?
A.
B.
C.
D.
17.  The cyclic form of glucose results from the formation of
A.
B.
C.
D.
18.  Refer to Exhibit 6A.  "Hindrate" is an inhibitor of triose phosphate isomerase.  When it is added to cells at a concentration of 0.1 nM, the enzyme's Km for the substrate is unchanged, but the apparent Vmax is altered to 50nM/sec. 
A.
B.
C.
D.
19.  The conditions required for maximum enzyme function are called:
A.
B.
C.
D.
20.  True or false:  Enzymes, being proteins, are sensitive to temperature and will be denatured by high temperatures.
A.
B.
21.  The structure below is shown in what anomeric form?
A.
B.
C.
D.
22.  Which form of monosaccharides is preferred by human cells?
A.
B.
C.
D.
23.  The carbohydrate below may be classified as
A.
B.
C.
D.
24.  In the induced-fit model of substrate binding to enzymes
A.
B.
C.
D.
25.  Which of the following inhibitors binds to the enzyme at a site other than the active site?
A.
B.
C.
D.
E.
26.  Which of the following terms is a general definition of an enzyme?
A.
B.
C.
D.
27.  Which statement about enzymes is incorrect?
A.
B.
C.
D.
28.  Which of the following terms can be used correctly to fill the blank in the following equation?  
A.
B.
C.
D.
29.  The synthesis of an enzyme in response to a cellular need is called
A.
B.
C.
D.
30.  A monosaccharide used to form nucleic acids is
A.
B.
C.
D.
31.  Competitive inhibitors have this effect:
A.
B.
C.
D.
E.
32.  Which of the following is a common function of many vitamins in the body?
A.
B.
C.
D.
33.  True or false:  Energy is generally consumed during anabolism
A.
B.
34.  If an inhibitor changes the slope of the Lineweaver-Burk graph, but not the x-intercept, it is this type of inhibition:
A.
B.
C.
D.
E.
35.  The value of Vmax changes in 
A.
B.
C.
D.
36.  A metal ion required for enzyme activity is called
A.
B.
C.
D.
37.  Draw the structure of B-D-Lactose in the Hawarth projection
A.
B.
C.
D.
38.  What happens to the entropy when ATP is hydrolyzed to ADP?
A.
B.
C.
D.
39.  The region of an enzyme where the substrate molecule fits is called the
A.
B.
C.
D.
40.  Which of the following is correctly called a complex carbohydrate?
A.
B.
C.
D.
41.  A polysaccharide containing B(14) linkages is
A.
B.
C.
D.
42.  The following compounds are enantiomers of each other
A.
B.
C.
D.
43.  The theory that proposes a somewhat flexible enzyme conformation is the 
A.
B.
C.
D.
44.  Structurally, glycogen is most similar to 
A.
B.
C.
D.
45.  The following represents the results of an experiment on a metabolic enzyme.  What is the optimum pH of this enzyme?
A.
B.
C.
D.
46.  Reactions requiring energy often occur with the simultaneous hydrolysis of
A.
B.
C.
D.
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