Bch211 - Exam 2

46 Questions  I  By Grj2010 on December 16, 2013
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1.  Competitive inhibitors have this effect:
A.
B.
C.
D.
E.
2.  True or false:  Enzymes, being proteins, are sensitive to temperature and will be denatured by high temperatures.
A.
B.
3.  Which of the following is correctly called a complex carbohydrate?
A.
B.
C.
D.
4.  If the y-intercept of a Lineweaver-Burk plot = 1.91 (sec/millimole) and the slope = 75.3L/sec, Km equals:
A.
B.
C.
D.
E.
5.  The structure below is shown in what anomeric form?
A.
B.
C.
D.
6.  True or false:  Aspirin acts as an reversible inhibitor of the COX 2 enzyme
A.
B.
7.  If the reaction AB has G = +15 Joule/mol and the reaction BC has G = -25 Joule/mol, the overall energy change AC will be  
A.
B.
C.
D.
E.
8.  The structure given below has what type of glycosidic linkage?
A.
B.
C.
D.
9.  The simplest carbohydrates are called
A.
B.
C.
D.
10.  Which of the following enzyme properties is explained by the lock-and-key model?
A.
B.
C.
D.
11.  The region of an enzyme where the substrate molecule fits is called the
A.
B.
C.
D.
12.  Refer to Exhibit 6A.  "Hindrate" is an inhibitor of triose phosphate isomerase.  When it is added to cells at a concentration of 0.1 nM, the enzyme's Km for the substrate is unchanged, but the apparent Vmax is altered to 50nM/sec. 
A.
B.
C.
D.
13.  The carbohydrate below may be classified as
A.
B.
C.
D.
14.  True or false:  Energy is generally consumed during anabolism
A.
B.
15.  The synthesis of an enzyme in response to a cellular need is called
A.
B.
C.
D.
16.  Sugars which contain an aldehyde group that can be oxidized are called
A.
B.
C.
D.
17.  What happens to the entropy when ATP is hydrolyzed to ADP?
A.
B.
C.
D.
18.  Which form of monosaccharides is preferred by human cells?
A.
B.
C.
D.
19.  The sign of Gibb's Free Energy is positive ("+") when energy is released
A.
B.
20.  Which of the following is a common function of many vitamins in the body?
A.
B.
C.
D.
21. 
  1. Lineweaver Burke - If everything else has a higher slope, anything lower than it represents the activation space.  everything above it represents the inhibition space
Gibbs free energy  delta G(negative - ) = spontaneous delta G(positive +) = nonspontaneous
A.
B.
C.
D.
22.  Draw the structure of B-D-Lactose in the Hawarth projection
A.
B.
C.
D.
23.  21000 molecules were acted on by a single molecule of an enzyme in 15 minutes.  What is the turnover number?
A.
B.
C.
D.
24.  Under saturation conditions, an enzyme-catalyzed reaction had a velocity V.  Which of the following would increase the rate of the reaction?
A.
B.
C.
D.
25.  The conditions required for maximum enzyme function are called:
A.
B.
C.
D.
26.  Which of the following is a disaccharide?
A.
B.
C.
D.
27.  A metal ion required for enzyme activity is called
A.
B.
C.
D.
28.  Reactions requiring energy often occur with the simultaneous hydrolysis of
A.
B.
C.
D.
29.  A polysaccharide containing B(14) linkages is
A.
B.
C.
D.
30.  The cyclic form of glucose results from the formation of
A.
B.
C.
D.
31.  A Lineweaver-Burk plot is useful in the analysis of enzymatic reactions because
A.
B.
C.
D.
32.  The following compounds are enantiomers of each other
A.
B.
C.
D.
33.  If an inhibitor changes the slope of the Lineweaver-Burk graph, but not the x-intercept, it is this type of inhibition:
A.
B.
C.
D.
E.
34.  Which statement about enzymes is incorrect?
A.
B.
C.
D.
35.  Which of the following terms is a general definition of an enzyme?
A.
B.
C.
D.
36.  In the induced-fit model of substrate binding to enzymes
A.
B.
C.
D.
37.  The theory that proposes a somewhat flexible enzyme conformation is the 
A.
B.
C.
D.
38.  Which of the following is true of a noncompetitive inhibitor?
A.
B.
C.
D.
39.  The following represents the results of an experiment on a metabolic enzyme.  What is the optimum pH of this enzyme?
A.
B.
C.
D.
40.  The following structure is shown in 
A.
B.
C.
D.
41.  Which of the following inhibitors binds to the enzyme at a site other than the active site?
A.
B.
C.
D.
E.
42.  A short description of a diastereomer would be?
A.
B.
C.
D.
43.  Which of the following terms can be used correctly to fill the blank in the following equation?  
A.
B.
C.
D.
44.  The value of Vmax changes in 
A.
B.
C.
D.
45.  Structurally, glycogen is most similar to 
A.
B.
C.
D.
46.  A monosaccharide used to form nucleic acids is
A.
B.
C.
D.
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