Bch211 - Exam 2

46 Questions  I  By Grj2010
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1.  Competitive inhibitors have this effect:
A.
B.
C.
D.
E.
2.  The carbohydrate below may be classified as
A.
B.
C.
D.
3.  The sign of Gibb's Free Energy is positive ("+") when energy is released
A.
B.
4.  The structure given below has what type of glycosidic linkage?
A.
B.
C.
D.
5.  If an inhibitor changes the slope of the Lineweaver-Burk graph, but not the x-intercept, it is this type of inhibition:
A.
B.
C.
D.
E.
6.  The value of Vmax changes in 
A.
B.
C.
D.
7.  Under saturation conditions, an enzyme-catalyzed reaction had a velocity V.  Which of the following would increase the rate of the reaction?
A.
B.
C.
D.
8.  21000 molecules were acted on by a single molecule of an enzyme in 15 minutes.  What is the turnover number?
A.
B.
C.
D.
9.  Structurally, glycogen is most similar to 
A.
B.
C.
D.
10.  Which of the following is a disaccharide?
A.
B.
C.
D.
11.  The synthesis of an enzyme in response to a cellular need is called
A.
B.
C.
D.
12.  True or false:  Aspirin acts as an reversible inhibitor of the COX 2 enzyme
A.
B.
13. 
  1. Lineweaver Burke - If everything else has a higher slope, anything lower than it represents the activation space.  everything above it represents the inhibition space
Gibbs free energy  delta G(negative - ) = spontaneous delta G(positive +) = nonspontaneous
A.
B.
C.
D.
14.  Which form of monosaccharides is preferred by human cells?
A.
B.
C.
D.
15.  The following structure is shown in 
A.
B.
C.
D.
16.  In the induced-fit model of substrate binding to enzymes
A.
B.
C.
D.
17.  What happens to the entropy when ATP is hydrolyzed to ADP?
A.
B.
C.
D.
18.  Reactions requiring energy often occur with the simultaneous hydrolysis of
A.
B.
C.
D.
19.  Which statement about enzymes is incorrect?
A.
B.
C.
D.
20.  Draw the structure of B-D-Lactose in the Hawarth projection
A.
B.
C.
D.
21.  The following compounds are enantiomers of each other
A.
B.
C.
D.
22.  A Lineweaver-Burk plot is useful in the analysis of enzymatic reactions because
A.
B.
C.
D.
23.  The theory that proposes a somewhat flexible enzyme conformation is the 
A.
B.
C.
D.
24.  Which of the following is a common function of many vitamins in the body?
A.
B.
C.
D.
25.  A metal ion required for enzyme activity is called
A.
B.
C.
D.
26.  The structure below is shown in what anomeric form?
A.
B.
C.
D.
27.  Which of the following terms is a general definition of an enzyme?
A.
B.
C.
D.
28.  True or false:  Enzymes, being proteins, are sensitive to temperature and will be denatured by high temperatures.
A.
B.
29.  If the y-intercept of a Lineweaver-Burk plot = 1.91 (sec/millimole) and the slope = 75.3L/sec, Km equals:
A.
B.
C.
D.
E.
30.  The region of an enzyme where the substrate molecule fits is called the
A.
B.
C.
D.
31.  The following represents the results of an experiment on a metabolic enzyme.  What is the optimum pH of this enzyme?
A.
B.
C.
D.
32.  Refer to Exhibit 6A.  "Hindrate" is an inhibitor of triose phosphate isomerase.  When it is added to cells at a concentration of 0.1 nM, the enzyme's Km for the substrate is unchanged, but the apparent Vmax is altered to 50nM/sec. 
A.
B.
C.
D.
33.  Which of the following inhibitors binds to the enzyme at a site other than the active site?
A.
B.
C.
D.
E.
34.  The cyclic form of glucose results from the formation of
A.
B.
C.
D.
35.  True or false:  Energy is generally consumed during anabolism
A.
B.
36.  The conditions required for maximum enzyme function are called:
A.
B.
C.
D.
37.  A polysaccharide containing B(14) linkages is
A.
B.
C.
D.
38.  Which of the following enzyme properties is explained by the lock-and-key model?
A.
B.
C.
D.
39.  A monosaccharide used to form nucleic acids is
A.
B.
C.
D.
40.  Sugars which contain an aldehyde group that can be oxidized are called
A.
B.
C.
D.
41.  The simplest carbohydrates are called
A.
B.
C.
D.
42.  A short description of a diastereomer would be?
A.
B.
C.
D.
43.  If the reaction AB has G = +15 Joule/mol and the reaction BC has G = -25 Joule/mol, the overall energy change AC will be  
A.
B.
C.
D.
E.
44.  Which of the following terms can be used correctly to fill the blank in the following equation?  
A.
B.
C.
D.
45.  Which of the following is true of a noncompetitive inhibitor?
A.
B.
C.
D.
46.  Which of the following is correctly called a complex carbohydrate?
A.
B.
C.
D.
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