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Quiz 2: DNA damage, repair and recombination

20 Questions  I  248 Attempts  I  Created By biomolfa 1112 days ago

Section F – DNA damage, repair and recombination


F1 Mutagenesis
F2 DNA damage
F3 DNA Repair
F4 Recombination


ACARA PRESENTASI KELOMPOK, Selasa, 18 Mei 2010

1. Presenter Kelompok 3 (Penyanggah Kelompok 5): Topik Mutations
2. Presenter Kelompok 4 (Penyanggah Kelompok 6): Topik DNA Repair
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Question Excerpt From Quiz 2: DNA damage, repair and recombination
Q.1)  Which of the following is TRUE about mutation
A.
B.
C.
D.
E.
Q.2) 

Mutations arise through spontaneous__________

I. in DNA replication

II. in meiotic recombination

III. as a consequence of the damaging effects of

physical or chemical agents on the DNA
A.
B.
C.
D.
E.
Q.3)  An alteration in a nucleotide sequence that changes a triplet coding for an amino acid into a termination codon.
A.
B.
C.
D.
E.
Q.4)  A point mutation that replaces a purine with another purine, or a pyrimidine with another pyrimidine.
A.
B.
C.
D.
E.
Q.5)  A point mutation that involves a purine being replaced by a pyrimidine, or vice versa.
A.
B.
C.
D.
E.
Q.6)  A change in a DNA sequence that has no effect on the expression or functioning of any gene or gene product.
A.
B.
C.
D.
E.
Q.7)  An alteration in a nucleotide sequence that converts a codon for one amino acid into a codon for a second amino acid.
A.
B.
C.
D.
E.
Q.8)  The frameshift mutations in genes can be produced by _________

I. transition

II. deletetion

III. insertion
A.
B.
C.
D.
E.
Q.9)  An alteration to the normal chemical or physical structure of the DNA.
A.
B.
C.
D.
E.
Q.10)  5-Bromouracil is an analog of ___________ that can react with deoxyribonucleic acid to produce a polymer with increased susceptibility to mutation.
A.
B.
C.
D.
E.
Q.11)  Cyclobutane pyrimidine dimers can be monomerized again by ________ in the presence of visible light.
A.
B.
C.
D.
E.
Q.12) 

All transposons encode a _________ which catalyzes the insertion.
A.
B.
C.
D.
E.
Q.13)  Small DNA sequences that can move to virtually any position in a cell’s genome.
A.
B.
C.
D.
E.
Q.14)  In base excision repair, the lesion is removed by __________
A.
B.
C.
D.
E.
Q.15) 

In nucleotide excision repair, an endonuclease makes nicks on either side of the lesion, which is then removed to leave a gap.  This gap is filled by __________ to makes the final phosphodiester bond.

I.DNA polymerase
II.DNA ligase
III. DNA glycolase
A.
B.
C.
D.
E.
Q.16)  Which of the following common examples of alkylating agents.
A.
B.
C.
D.
E.
Q.17)  The exchange of nonhomologous regions of DNA at specific sites is independent of _________
A.
B.
C.
D.
E.
Q.18)  The dispersed repetitive sequences found in higher eukaryotic DNA (e.g. LINES and SINES) probably spread through the genome by _________
A.
B.
C.
D.
E.
Q.19)  The enzyme of Escherichia coli is a nuclease that initiates the repair of double-stranded DNA breaks by homologous recombination.
A.
B.
C.
D.
E.
Q.20)  Which of the following DNA mutation that result in the appearance of a stop codon in the resulting mRNA. synthesis.
A.
B.
C.
D.
E.

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