Quiz 2: Dna Damage, Repair And Recombination

20 Questions  I  By Biomolfa
Section F – DNA damage, repair and recombination F1 Mutagenesis F2 DNA damage F3 DNA Repair F4 Recombination ACARA PRESENTASI KELOMPOK, Selasa, 18 Mei 20101. Presenter Kelompok 3 (Penyanggah Kelompok 5): Topik Mutations2. Presenter Kelompok 4 (Penyanggah Kelompok 6): Topik DNA Repair

  
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1.  Which of the following is TRUE about mutation
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B.
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2.  Mutations arise through spontaneous__________ I. in DNA replication II. in meiotic recombination III. as a consequence of the damaging effects of physical or chemical agents on the DNA
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B.
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D.
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3.  An alteration in a nucleotide sequence that changes a triplet coding for an amino acid into a termination codon.
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B.
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4.  A point mutation that replaces a purine with another purine, or a pyrimidine with another pyrimidine.
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B.
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D.
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5.  A point mutation that involves a purine being replaced by a pyrimidine, or vice versa.
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6.  A change in a DNA sequence that has no effect on the expression or functioning of any gene or gene product.
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7.  An alteration in a nucleotide sequence that converts a codon for one amino acid into a codon for a second amino acid.
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8.  The frameshift mutations in genes can be produced by _________ I. transition II. deletetion III. insertion
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9.  An alteration to the normal chemical or physical structure of the DNA.
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10.  5-Bromouracil is an analog of ___________ that can react with deoxyribonucleic acid to produce a polymer with increased susceptibility to mutation.
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11.  Cyclobutane pyrimidine dimers can be monomerized again by ________ in the presence of visible light.
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12.  All transposons encode a _________ which catalyzes the insertion.
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13.  Small DNA sequences that can move to virtually any position in a cell’s genome.
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14.  In base excision repair, the lesion is removed by __________
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15.  In nucleotide excision repair, an endonuclease makes nicks on either side of the lesion, which is then removed to leave a gap.  This gap is filled by __________ to makes the final phosphodiester bond. I.DNA polymerase II.DNA ligase III. DNA glycolase
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16.  Which of the following common examples of alkylating agents.
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17.  The exchange of nonhomologous regions of DNA at specific sites is independent of _________
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18.  The dispersed repetitive sequences found in higher eukaryotic DNA (e.g. LINES and SINES) probably spread through the genome by _________
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19.  The enzyme of Escherichia coli is a nuclease that initiates the repair of double-stranded DNA breaks by homologous recombination.
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20.  Which of the following DNA mutation that result in the appearance of a stop codon in the resulting mRNA. synthesis.
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B.
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D.
E.
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