Congenital Disorders Of Spleen

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Congenital Disorders Of Spleen - Quiz

Quiz 2 for packet 1 of spleen


Questions and Answers
  • 1. 

    This is a mirror image condition, known as _______  __________.

    Explanation
    Situs inversus is a medical condition where the internal organs are mirrored or reversed from their normal positions. In this condition, the organs that are usually on the left side of the body are found on the right side, and vice versa. This mirror image condition is known as situs inversus.

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  • 2. 

    The normal arrangement of visceral organs is known as _______  ________.

    Explanation
    The normal arrangement of visceral organs in the body is referred to as situs solitus. This term describes the typical positioning and orientation of organs within the abdominal and thoracic cavities. It is important for proper functioning and development of the body that the organs are in their correct positions. Any deviation from situs solitus can lead to various medical conditions and complications.

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  • 3. 

    _________________ spleen is a rare developmental anomaly in which the spleen is abnormally positioned and the spleen may move around within the abdominal cavity, leading to increased risk of torsion.

    Explanation
    Wandering spleen is a rare developmental anomaly where the spleen is abnormally positioned and can move around within the abdominal cavity. This condition increases the risk of torsion, which can cause severe complications.

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  • 4. 

    Wandering spleen is also known as _________ spleen or _________ spleen.

    Explanation
    The condition known as wandering spleen is alternatively referred to as floating spleen or aberrant spleen. This suggests that the spleen is not in its normal position and has moved or shifted to an abnormal location within the abdomen. The terms "floating" and "aberrant" both describe this displacement of the spleen from its usual anatomical position.

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  • 5. 

    In this condition, the spleen is small and non functioning due to a chronic condition; NOT congenital. This results from repeated splenic infarctions such as with sickle cell anemia, celiac disease, or thyrotoxicosis.

    Explanation
    The correct answer is acquired hypoplasia. In this condition, the spleen is small and non-functioning due to a chronic condition, not a congenital one. This can occur as a result of repeated splenic infarctions, such as those seen in sickle cell anemia, celiac disease, or thyrotoxicosis. Functional hypoplasia refers to a condition where the spleen is small but still functions properly, which is not the case in this scenario.

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  • 6. 

    ____________ is death or necrosis due to loss of blood supply.

    Explanation
    Infarction refers to the death or necrosis of a tissue or organ caused by the loss of blood supply. When blood flow to a specific area is blocked or reduced, it leads to oxygen and nutrient deprivation, resulting in tissue damage or death. Infarction can occur in various parts of the body, such as the heart, brain, or kidneys, and is commonly associated with conditions like heart attacks or strokes.

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  • 7. 

    This occurs with chronic hyperthyroidism.

    Explanation
    Thyrotoxicosis is a condition characterized by excessive production of thyroid hormones. Chronic hyperthyroidism, which refers to a long-term overactive thyroid gland, is one of the causes of thyrotoxicosis. In this condition, the thyroid gland produces an excessive amount of thyroid hormones, leading to symptoms such as weight loss, increased heart rate, tremors, and anxiety. Therefore, thyrotoxicosis is the correct answer as it accurately describes the condition of excessive thyroid hormone production in the context of chronic hyperthyroidism.

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  • 8. 

    _____________ disease is an intestinal malabsorption syndrome characterized by diarrhea, malaise, and hypocalcemia.

    Explanation
    Celiac disease is an autoimmune disorder that affects the small intestine, causing an inability to properly absorb nutrients from food. This leads to symptoms such as chronic diarrhea, fatigue, and low levels of calcium in the blood (hypocalcemia). The immune system mistakenly reacts to gluten, a protein found in wheat, barley, and rye, damaging the lining of the small intestine. This damage interferes with the absorption of nutrients, resulting in the characteristic symptoms of celiac disease.

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  • 9. 

    Sono Appearance of acquired hypoplasia is characterized as a small, _______ spleen; fibrotic and ________.

    Explanation
    Acquired hypoplasia refers to the underdevelopment or reduction in size of an organ or tissue that occurs after birth. In the case of the spleen, acquired hypoplasia is characterized by a small size and a fibrotic, or scarred, appearance. The term "echogenic" refers to the ability of a structure to produce echoes in an ultrasound examination, indicating a high level of reflectivity. Therefore, an echogenic spleen would appear bright or dense on an ultrasound image. On the other hand, "calcified" means that calcium deposits have formed within the tissue, resulting in a hardened or calcified appearance. Therefore, in the context of acquired hypoplasia of the spleen, the correct answer is echogenic and calcified.

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  • 10. 

    This is a rare congenital condition in which there are multiple spleens; usually there are 2 larger spleens with a bunch of smaller one. This is known as ___________.

    Explanation
    Polysplenia is a rare congenital condition characterized by the presence of multiple spleens, typically consisting of two larger spleens along with several smaller ones. This condition is also known as multiple spleens.

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  • 11. 

    Polysplenia is associated with "bilateral ______  sidedness."

    Explanation
    Polysplenia is a condition characterized by the presence of multiple spleens. It is associated with "bilateral left-sidedness" which means that the organs in the body are positioned on the left side instead of the normal right side. This can include the liver, stomach, and intestines being located on the left side of the body. It is a rare condition that can be identified through imaging tests and may be associated with other congenital abnormalities.

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  • 12. 

    In bilateral left sidedness syndrome, structures on the left side of the body are more ___________.  This condition includes multiple spleens, 2 left lungs, absent GB, possible bilairy atresia, GI malrotation, liver located centrally or on left side, and cardiac abnomalities.

    Explanation
    In bilateral left sidedness syndrome, the structures on the left side of the body are more developed or prominent compared to the right side. This can be seen in the presence of multiple spleens, two left lungs, absence of the gallbladder, possible biliary atresia, gastrointestinal malrotation, central or left-sided location of the liver, and cardiac abnormalities.

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  • 13. 

    Asplenia is associated with " __________  ________  __________  syndrome."

    Explanation
    Asplenia is associated with bilateral right sidedness syndrome. This means that individuals with asplenia, a condition where the spleen is absent or non-functional, are also likely to have a syndrome characterized by the presence of organs or structures that are normally located on the right side of the body. This association suggests a possible developmental connection between the absence of the spleen and the abnormal positioning of organs on the right side.

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  • 14. 

    __________ is a rare congenital absence of the spleen; associated with congenital heart defects and ______  _______.

    Explanation
    Asplenia is a rare congenital condition where the spleen is absent. It is often associated with congenital heart defects and situs inversus, which is a condition where the organs are positioned in a mirror image of their normal arrangement.

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  • 15. 

    This is a syndrome in which structures on the right side are more dominant and is associated with an absent spleen, midline liver and GB, reversed aorta and IVC, horseshoe Kidneys, and congenital heart disease.

    Explanation
    Bilateral right sidedness refers to a syndrome where structures on the right side of the body are more dominant. This syndrome is characterized by various abnormalities such as an absent spleen, midline liver and gallbladder, reversed aorta and inferior vena cava, horseshoe kidneys, and congenital heart disease. Essentially, it means that the normal left-right asymmetry of the body is reversed, with the right side becoming more dominant.

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  • 16. 

    Check all that apply to the differential diagnosis of accesory spleen:

    • A.

      Pancreatic tail pathology

    • B.

      Left adrenal pathology

    • C.

      Pathology of upper pole of left kidney

    • D.

      Enlarged lymoh nodes around spleen

    Correct Answer(s)
    A. Pancreatic tail pathology
    B. Left adrenal pathology
    C. Pathology of upper pole of left kidney
    D. Enlarged lymoh nodes around spleen
    Explanation
    The accessory spleen is a congenital anomaly where small nodules of splenic tissue are found outside the normal spleen. It is important to consider the possibility of an accessory spleen when evaluating certain pathologies. Pancreatic tail pathology, left adrenal pathology, and pathology of the upper pole of the left kidney can mimic an accessory spleen on imaging studies. Additionally, enlarged lymph nodes around the spleen can also be mistaken for an accessory spleen. Therefore, all of these options should be considered in the differential diagnosis of an accessory spleen.

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  • 17. 

    This is a very common normal variant, most commonly found at the splenic hilum, and usually measure 1-3 cm in size.

    Correct Answer(s)
    accessory spleen
    Explanation
    This answer suggests that the correct term for the given description is "accessory spleen." An accessory spleen is a normal variant that is commonly found at the splenic hilum, which is the area where blood vessels enter and exit the spleen. These accessory spleens are typically small, measuring between 1-3 cm in size.

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  • 18. 

    When a splenectomy is performed, and the accessory spleen is not removed, it may enlarge and is known as the "_____  _______" spleen.

    Correct Answer(s)
    born again
  • 19. 

    Sono appearance of accessory spleen:

    • A.

      Small, round homogenous nodules isoechoic to spleen

    • B.

      Should be low resistance doppler

    • C.

      Same characteristic color flow in accessory spleen

    Correct Answer(s)
    A. Small, round homogenous nodules isoechoic to spleen
    B. Should be low resistance doppler
    C. Same characteristic color flow in accessory spleen
    Explanation
    The correct answer is "small, round homogenous nodules isoechoic to spleen, should be low resistance doppler, same characteristic color flow in accessory spleen." This answer suggests that the appearance of accessory spleen is characterized by small, round nodules that have a similar echogenicity to the spleen. Additionally, there should be low resistance doppler flow and the accessory spleen should have the same characteristic color flow as the spleen.

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  • 20. 

    True cysts of the spleen are rare and congenital.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    True cysts of the spleen are indeed rare and congenital. This means that they are not common and are present from birth.

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  • 21. 

    These are true cysts of the spleen lined with squamous epithelium and they typically appear as a solitary cyst averaging 10cm in size.

    Correct Answer
    epidermoid cysts
    epidermoid
    Explanation
    Epidermoid cysts are true cysts of the spleen that are lined with squamous epithelium. They are typically solitary and have an average size of 10cm.

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  • 22. 

    This is an inherited condition, autosomal dominant,  associated with cysts in the spleen, liver, and pancreas.

    Correct Answer
    adult polycystic kidney disease
    polycystic kidney disease
    Explanation
    This condition is inherited in an autosomal dominant manner, meaning that if one parent has the condition, there is a 50% chance of passing it on to each child. It is characterized by the presence of cysts in the spleen, liver, and pancreas, in addition to the kidneys. The term "adult" is used to differentiate it from another form of polycystic kidney disease that affects children. Therefore, both "adult polycystic kidney disease" and "polycystic kidney disease" are correct answers for this question.

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  • 23. 

    Epidermoid cysts usually have a "swiss cheese" appearance and usually are multiple in number.

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    adult polycystic kidney disease usually has "swiss cheese" appearance and cysts are multiple

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  • 24. 

    With epidermoid cysts, the walls may be __________ and the internal contents may appear _____________ due to cholesterol crystals.

    Correct Answer
    calcified, echogenic
    Explanation
    Epidermoid cysts are benign growths that form beneath the skin. When these cysts become calcified, it means that calcium deposits have formed in the walls of the cyst. This calcification can make the walls of the cyst appear harder and more rigid. Additionally, the internal contents of the cyst, which may include dead skin cells and oils, can become echogenic. Echogenicity refers to the ability of a substance to reflect ultrasound waves, and in this case, it is due to the presence of cholesterol crystals.

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  • 25. 

    _____________ cysts are the most common splenic cysts worldwide.  They are more common than congenital cysts.

    Correct Answer
    parasitic
    Explanation
    Parasitic cysts are the most common type of splenic cysts globally, surpassing the prevalence of congenital cysts. These cysts are caused by parasitic infections, where organisms such as parasites or their larvae invade the spleen and form cysts. The high prevalence of parasitic cysts can be attributed to factors such as poor sanitation, inadequate hygiene practices, and exposure to contaminated water or food sources. These cysts can cause various symptoms and complications, depending on the size and location, and may require medical intervention for diagnosis and treatment.

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  • 26. 

    What is the name of the only parasite that forms cysts in the spleen?

    Correct Answer
    echinococcus
    Explanation
    Echinococcus is the correct answer because it is the only parasite known to form cysts in the spleen. This parasite belongs to the genus Echinococcus and can cause a disease called echinococcosis. It primarily affects the liver and lungs, but in some cases, it can also form cysts in the spleen. These cysts can lead to various symptoms and complications if left untreated. Therefore, echinococcus is the name of the only parasite that forms cysts in the spleen.

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  • 27. 

    ____________ disease results in the formation of an echinococcal cyst

    Correct Answer
    hydatid
    Explanation
    Hydatid disease, also known as echinococcosis, is caused by the infection of the larval stage of the tapeworm Echinococcus. The disease results in the formation of an echinococcal cyst, which is a fluid-filled sac that develops in various organs, most commonly the liver and lungs. The cysts can grow and cause symptoms such as pain, organ dysfunction, and even rupture, leading to life-threatening complications. Treatment usually involves surgical removal of the cysts and the use of antiparasitic medications.

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  • 28. 

    Check all that apply to the sono appearance ofparasitic cysts:

    • A.

      Cyst within a cyst

    • B.

      May have hydatid sand

    • C.

      Daughter cysts can attach via stalk or outpouching of main cyst

    • D.

      Water lily sign

    • E.

      Final stages: collapsed and calcified --> granuloma

    Correct Answer(s)
    A. Cyst within a cyst
    B. May have hydatid sand
    C. Daughter cysts can attach via stalk or outpouching of main cyst
    D. Water lily sign
    E. Final stages: collapsed and calcified --> granuloma
    Explanation
    The sono appearance of parasitic cysts can include the following features: cyst within a cyst, presence of hydatid sand, attachment of daughter cysts via stalk or outpouching of the main cyst, water lily sign, and in the final stages, the cyst may collapse and calcify, forming a granuloma.

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  • 29. 

    Symptoms of parasitic cysts

    • A.

      RUQ pain

    • B.

      Slight increase in AST

    • C.

      Cirrhosis

    • D.

      Hepatosplenomegaly

    • E.

      Slight increase in ALP

    • F.

      Fever

    Correct Answer(s)
    A. RUQ pain
    D. Hepatosplenomegaly
    E. Slight increase in ALP
    Explanation
    The given symptoms of RUQ pain, hepatosplenomegaly, and a slight increase in ALP are suggestive of parasitic cysts. RUQ pain refers to pain in the right upper quadrant of the abdomen, which can be caused by the presence of cysts. Hepatosplenomegaly refers to the enlargement of the liver and spleen, which can also be a result of parasitic cysts. A slight increase in ALP (alkaline phosphatase) levels can be seen in cases of liver involvement due to parasitic cysts. Therefore, these symptoms together indicate the presence of parasitic cysts.

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  • 30. 

    Parasitic cysts cannot be aspirated because patient may go into anaphylactic shock

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Parasitic cysts cannot be aspirated because they may contain allergenic substances that can cause an anaphylactic shock in the patient. Aspiration involves inserting a needle into the cyst to drain its contents, but in the case of parasitic cysts, this can release the parasites or their antigens into the bloodstream, triggering a severe allergic reaction. Therefore, it is true that parasitic cysts cannot be aspirated to avoid the risk of anaphylactic shock.

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  • 31. 

    Hydatid disease is transmitted via ______.

    Correct Answer
    feces
    Explanation
    Hydatid disease, also known as echinococcosis, is caused by the tapeworm Echinococcus. The tapeworm's eggs are shed in the feces of infected animals, such as dogs and livestock. These eggs can contaminate the environment, including soil, water, and vegetation, and can be ingested by humans through contaminated food, water, or direct contact with infected animals. Once ingested, the eggs hatch in the intestines and the larvae migrate to various organs, forming cysts and causing hydatid disease. Therefore, the correct answer is feces.

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  • 32. 

    Hydatid disease is common in _______, _________, and ______ raising countries.

    Correct Answer
    sheep, cattle, pig
    Explanation
    Hydatid disease is caused by a parasitic infection from the tapeworm Echinococcus granulosus. The tapeworm's eggs are found in the feces of infected dogs, and when ingested by intermediate hosts such as sheep, cattle, and pigs, they develop into cysts primarily in the liver and lungs. Therefore, hydatid disease is common in countries where these intermediate hosts are prevalent, as they serve as a reservoir for the tapeworm's life cycle.

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  • 33. 

    ____________ is a collection of fluid without an epithelial lining; is a pancreatic cyst; spleen is usually involved beacause of its close proximity to the pancreas.

    Correct Answer
    pseudocyst
    Explanation
    A pseudocyst is a collection of fluid without an epithelial lining. It is commonly found in the pancreas and is often associated with the spleen due to its close proximity to the pancreas.

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  • 34. 

    Sono appearance of psuedocyst:

    • A.

      Varies

    • B.

      May be anechoic, have low level echoes or septations

    • C.

      Can calcify in late stages

    Correct Answer(s)
    A. Varies
    B. May be anechoic, have low level echoes or septations
    C. Can calcify in late stages
    Explanation
    The appearance of a pseudocyst in the sono varies and can have different characteristics. It may be anechoic, meaning it appears as a black or empty area on the ultrasound image. It can also have low level echoes, which means there are some echoes but they are not very strong. Additionally, pseudocysts may have septations, which are thin dividing walls within the cyst. In late stages, the pseudocyst can calcify, meaning it develops calcium deposits.

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  • 35. 

    Because of the vascularity, pseudocysts may erode the vessels, causing pseudoaneurysms and bleeings into the pseudocysts.

    • A.

      True

    • B.

      False

    Correct Answer
    A. True
    Explanation
    Pseudocysts are fluid-filled sacs that can form in different parts of the body, including the pancreas. These cysts are known to be highly vascular, meaning they have a lot of blood vessels. Due to this vascularity, pseudocysts can erode the vessels surrounding them, leading to the formation of pseudoaneurysms (abnormal bulges in the weakened vessel walls) and bleeding into the pseudocysts. Therefore, the statement that pseudocysts may erode vessels, causing pseudoaneurysms and bleeding into the pseudocysts is true.

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  • 36. 

    Splenic ________ are associated with general sepsis in 80% of cases; however in immunocompromised patient, the _______ (organ) may be the only site of _________.

    Correct Answer
    abscesses, spleen, infection
    Explanation
    Splenic abscesses are commonly linked to general sepsis in 80% of cases. However, in immunocompromised patients, the spleen may be the sole site of infection.

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  • 37. 

    What are the 3 symptoms of splenic abscess? (alphabetically)

    Correct Answer
    abdominal pain, fever, leukocytosis
    Explanation
    The three symptoms of splenic abscess are abdominal pain, fever, and leukocytosis. Abdominal pain is a common symptom and is often described as a dull or sharp pain in the left upper quadrant of the abdomen. Fever is another symptom, which is characterized by an elevated body temperature above the normal range. Leukocytosis refers to an increased number of white blood cells in the blood, which is a sign of infection or inflammation. These three symptoms together can indicate the presence of a splenic abscess.

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  • 38. 

    Splenic abscesses may have some ________  components but otherwise is a complex _______mass with __________ (irregular or regular) borders. Dirty shadowing is seen because of ______

    Correct Answer
    solid, cystic, irregular, gas
    Explanation
    A splenic abscess is a complex mass in the spleen that can have both solid and cystic components. The borders of the abscess can be irregular, indicating the presence of infection or inflammation. The presence of gas within the abscess can cause dirty shadowing on imaging.

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  • 39. 

    Commonly with splenic abscess, you may see reactive _______  ________ because the spleen is in contact with the diaphragm.

    Correct Answer
    pleural effusion
    Explanation
    With splenic abscess, there is a possibility of the infection spreading to the surrounding structures, including the diaphragm. The spleen is located in close proximity to the diaphragm, and as a result, a common complication of splenic abscess is the development of pleural effusion. Pleural effusion refers to the accumulation of fluid in the pleural space, which is the space between the lungs and the chest wall. This can occur due to the spread of infection or inflammation from the spleen to the diaphragm, leading to the accumulation of fluid in the pleural space.

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  • 40. 

    Most common abscesses to invade spleen

    • A.

      Subphrenic

    • B.

      Perinephric

    • C.

      Perforated gastric abscesses

    • D.

      Pancreatic

    Correct Answer(s)
    A. Subphrenic
    B. Perinephric
    C. Perforated gastric abscesses
    D. Pancreatic
    Explanation
    The given answer lists the most common abscesses that can invade the spleen. Subphrenic abscesses refer to infections that occur in the space between the diaphragm and the upper abdominal organs, which can spread to the spleen. Perinephric abscesses are infections that develop around the kidneys and can also extend to the spleen. Perforated gastric abscesses occur when a hole forms in the stomach due to infection, and the abscess can then spread to the spleen. Lastly, pancreatic abscesses can also invade the spleen if the infection spreads. These are all potential sources of infection that can affect the spleen.

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