Chromosomes And Recombination
Mccabe lecture on chromosomes and recombination
- 1.
Indications for ordering a chromosome analysis include:
- A.
Growth and development abnormalities
- B.
Family history of chromosomal abnormalities
- C.
Infertility, still births, or neonatals death
- D.
Pregnancy with advanced maternal age
- E.
All of the above
Correct Answer
E. All of the above -
- 2.
__________ is any chromosome number other than 46
Correct Answer
heteroploid
heteroploidy - 3.
Triploidy is most often due to ________________
Correct Answer
fertilization with two sperm
dispermy - 4.
A complete mole is:
- A.
Diploid and has chromosomes all from paternal origin
- B.
Has a small atrophic fetus
- C.
Contains no fetus or placenta
- D.
Has an extra paternal chromosome set
- E.
A and C only
Correct Answer
E. A and C only -
- 5.
Tetraploidy is always __________ or ____________
Correct Answer
92, xxxx
92, xxyy - 6.
Aneuploidies are due to ___________________
Correct Answer
nondisjunction - 7.
If there are one or more crossovers, then the ratio of non-recombinant: recombinant genotypes will be:
- A.
1:2
- B.
2:1
- C.
1:1
- D.
1:3
- E.
Unknown
Correct Answer
C. 1:1 -
- 8.
Genetic linkage analysis is based on:
- A.
PCR and computer analysis
- B.
Probability of meiotic recombination events
- C.
Physical map of the DNA making up the chromosome
- D.
Number of people in a population
- E.
Patchwork inheritance pattern of DNA
Correct Answer
B. Probability of meiotic recombination events -
- 9.
FISH :
- A.
Detects a specific positions on a chromosome
- B.
Paints whole chromosomes
- C.
Stands for fluorescence in situ hybridization
- D.
A and C
- E.
B and C
Correct Answer
D. A and C -
- 10.
Possible manifestations of Down Syndrome are
- A.
Transverse palmar crease and flat wide bridge of nose
- B.
Microcephaly, and protruding tongue
- C.
Acute lympocytic leukemia
- D.
A, B, and C
- E.
A and C only
Correct Answer
D. A, B, and C -
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May 20, 2019Quiz Edited by
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