Saving Lives With Antibody Titer Tests


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Saving Lives With Antibody Titer Tests - Quiz

Dr. Ronald Schultz, Professor and Chair of the Department of Pathobiological Sciences at the School of Veterinary Medicine, University of Wisconsin-Madison, discusses the use of antibody titer tests in animal sheltering as well as in private practice.


Questions and Answers
  • 1. 

    We hope that you enjoyed the video presentation. A certificate of attendance in your name will be awarded at the end of this quiz. To assure us that you have viewed the entire presentation, please check the box below.

    • A.

      I certify that I have listened to the entire presentation.

    Correct Answer
    A. I certify that I have listened to the entire presentation.
  • 2. 

    Antibody plays a critical role in protective immunity for the following canine diseases:

    • A.

      Canine distemper

    • B.

      Canine parvovirus

    • C.

      Canine adenovirus

    • D.

      Rabies virus

    • E.

      All of the above

    Correct Answer
    E. All of the above
  • 3. 

    The following types of tests are used to measure protective immunity after vaccination with certain of the vaccine viruses:

    • A.

      Virus neutralization (VN)

    • B.

      Hemagglutination inhibition (HI)

    • C.

      Enzyme linked immunosorbent assay (ELISA)

    • D.

      (a), (b) and (c)

    • E.

      None of the above

    Correct Answer
    D. (a), (b) and (c)
  • 4. 

    You should not use antibody tests to measure protective immunity from vaccination in:

    • A.

      Puppies less than 16 weeks of age

    • B.

      Kittens less than 16 weeks of age

    • C.

      Both (a) and (b)

    • D.

      Dogs and cats older than 15 years

    • E.

      Dogs or cats that have never been vaccinated

    Correct Answer
    C. Both (a) and (b)
  • 5. 

    An antibody positive test, when used to measure antibody to CDV in a one year old dog that has never been vaccinated, shows that:

    • A.

      The dog has maternally derived antibody (MDA)

    • B.

      The dog is immune to CDV

    • C.

      The dog was apparently naturally infected, with or without disease signs and is immune

    • D.

      Both (b) and (c)

    • E.

      None of the above are correct

    Correct Answer
    D. Both (b) and (c)
  • 6. 

    You received a titer for CPV and CDV from the Diagnostic Lab from a dog that was vaccinated 8 years ago.  The titer for CPV is 1280 and for CDV is 64.  These results indicate the following: 

    • A.

      The dog has antibody to the 2 viruses and is immune

    • B.

      The dog is more susceptible to CDV than CPV

    • C.

      The dog needs to be revaccinated with a product containing CDV and CPV

    • D.

      The dog is susceptible to CDV but not CPV

    • E.

      The dog has 20 times more antibody to CPV than CDV

    Correct Answer
    A. The dog has antibody to the 2 viruses and is immune
  • 7. 

    The titers for the above dog indicate that the real titer for CDV and CPV-2 are:

    • A.

      CDV titer is 32 to 128

    • B.

      CPV titer is 640 to 2560

    • C.

      The titers show the dog is immune

    • D.

      The titers show the dog did not need to be revaccinated with CDV or CPV to maintain titers

    • E.

      All of the above

    Correct Answer
    E. All of the above
  • 8. 

    Why are titers not routinely used for CDV and CPV in lieu of revaccination?

    • A.

      They are often too expensive

    • B.

      Titers are poorly understood

    • C.

      It is easier to revaccinate than have a titer performed

    • D.

      (a), (b) and (c)

    • E.

      They do not correlate with immunity

    Correct Answer
    D. (a), (b) and (c)
  • 9. 

    When a shelter is having a CDV outbreak, how can titers be used to control the outbreak?

    • A.

      Only allow dogs over 16 to 20 weeks of age with antibody to enter the shelter or the part of the shelter where the outbreak is present

    • B.

      Keep puppies less than 16 to 20 weeks out of the shelter when possible, regardless of antibody status

    • C.

      Dogs already in the shelter over 16 to 20 weeks that have been vaccinated and have antibody can remain

    • D.

      Do not send dogs for adoption/fostering that have been in the shelter and are antibody neg

    • E.

      All of the above

    Correct Answer
    E. All of the above
  • 10. 

    Why can’t antibody titers be used to control outbreaks of canine and feline infectious respiratory disease complex (aka Kennel Cough, Upper Respiratory Infections)?

    • A.

      Serum titers to mucosal pathogens don’t correlate with protection

    • B.

      These diseases are caused by multiple microbial agents and other factors

    • C.

      These diseases are not vaccine preventable, thus titers are of limited value

    • D.

      All of the above

    • E.

      There are no tests available to measure antibody to the pathogens causing these disorders!

    Correct Answer
    D. All of the above
  • 11. 

    If you were given the following options, which would you choose for a dog that has received its puppy vaccines and has returned for its one year exam?

    • A.

      Revaccinate the animal with CDV/CPV/CAV

    • B.

      Perform an antibody test for CDV/CPV/CAV

    • C.

      Perform an antibody test, then revaccinate if it shows the animal is not immune

    • D.

      A and B

    • E.

      None of the above

    Correct Answer
    C. Perform an antibody test, then revaccinate if it shows the animal is not immune

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  • Mar 18, 2022
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