Osteoarthritis (Msq Drill 158)

2. Post traumatic causes of osteoarthritis can be divided into acute, repetitive and posteoperative. What would a fracture through a joint be classified as?

Acute

Repetitive

Postoperative

3. How would you classify an occupational injury?

Acute

Repetitive

Post operative

6. Many biproducts formed in the cascade that is initiated by chemokine release by the chondrocyte promote futher catabolism of the cartilage. True or false?

True

False

7. Developmental disorders, metabolic diseases, nutrition and chondropenia are also endogenous contributing factors to the development of OA. True or false?

True

False

11. What is the inflammation evident in osteoarthritis due to?

Increased immune modulating cells due to synovitis

Proliferation of surrounding immune cells due to excessive bone destroyal

Inflammation secondary to cartilage degradation

12. Patients with osteoarthritis complain of joint stiffness. How long does this stiffness usually last?

For most of the day

For a very short period of time after getting up

16. Whereas all the activity is in the synovium in Rheumatoid arthritis, all the activity in the _______ with osteoarthritis.

Synovium

Bone

Cartillage

18. Which of the following occur due to osteoarthritis?

Softening and ulceration of articular cartillage

Loss of articular cartillage

Sclerosis of subchondral bone

Osteophytes

Subchondral cysts

Submit

19. Which of the following causes of secondary osteoarthritis is the most common cause of secondary osteoarthritis?

Dysplastic

Skeletal failue

Post traumatic

Post inflammatory

Osteonecrosis

20. Which of the following are also causes of secondary osteoarthritis?

Endocrine and metabolic

Hematochromatosis

Connective tissue diseases

Endemic diseases

Miscallaneous causes

hematochromatosis - increased iron deposition.

Explanation

hematochromatosis - increased iron deposition.

Submit

22. Pro inflammatory sytokines and meditors produced by chrondrocytes act within cartilage to:

Promote bone remodelling

To promote catabolism

To promote anabolism of cartilage

23. Hyaluronic acid has a unique combination of which two elements that are critical for joint function?

Elasticity

Viscosity

Hydration

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25. What percentage of people over 65 have knee osteoarthritis that is evident on x-rays?

One quarter

One half

One third

27. Synovitis is associated with osteoarthritis. True or false?

True

False

Osteoarthritis is non-inflammatory.

Explanation

Osteoarthritis is non-inflammatory.

28. One of the most common causes of inflammation is osteoarthritis is:

IL-1B

TNF-alpha

IL-6

IL-8

29. What is the most commonly affected joint by osteoarthritis?

1st DIP

1st metarcarpal phalyngeal joint

2nd PIP

2nd metacarpal phalangeal joint

30. If you looked at the synovial fluid of a patient with osteoarthrities what would you observe?

More cell count

Normal cell count

Less cell count

There is no inflammation so the number of cells will NOT increase.

Explanation

There is no inflammation so the number of cells will NOT increase.

31. Post traumatic causes of osteoarthritis can be divided into which classifications?

Acute

Subacute

Repetitive

Postoperative

Submit

32. Which of the following are mechanical factors that can contribute to OA?

Genetic disorders

Loss of muscle strength

Joint structure

Obesity

Overuse and trauma

Obesity and genetic disorders are endogenous contributing factors for the development of OA.

Explanation

Obesity and genetic disorders are endogenous contributing factors for the development of OA.

Submit

33. Which of the folowing are other findings associated with osteoarthritis?

Gel phenomenon

Joint pain and tenderness

No crepitus

Bony swelling abd angulation deformities

Functional impairment

patients with OA will sometimes have crepitus.

Explanation

patients with OA will sometimes have crepitus.

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