Musculoskeletal Tumors (Msq Drill 148)

1. On X-ray you see a lytic tumor with permeative margins and extension into the soft tissues. True or false?

True

False

2. Osteochromas are mosr common in:

Young patients

Plder patients

3. On x-ray endochondroma is a radioluscent nodule surrounded by a thin rim of bone. True or false?

True

False

4. Microscopically endochondroma are lobules or mature hyaline cartilage. True or false?

True

False

5. Ewing sarcoma and Primitive Neuroectodermal tumor (PNET) share a common chromosomal translocation and may be viewed as the same tumor with just a difference in neural differentiation. True or false?

True

False

6. What is the most frequent malignant bone neoplasm?

Osteoid osteoma

Osteosarcoma

Osteoblastoma

7. So, Ewing sarcoma and PNET are benign or malignant?

Benign

Malignant

8. The gross structure of osteoid osteomas and osteoblastoma is: round to oval well circumscribed nidus of hemmorhagic gritty tan tissue surrounded by sclerotic bone. True or flase?

True

False

9. Which is more responsive to aspirin between osteoid osteoma and osteoblastoma?

Osteoid osteoma

Osteoblastoma

10. Ewing sarcoma and PNET arise in the medullary cavity, do they also invade the cortex and periosteum?

Yes

No

11. Most patients with Ewing sarcoma or PNET are over or under the age of 20?

Under 20

Over 20

12. Who is affected more by ewing sarcoma and PNET between males and females?

Males

Females

13. Microscopically osteochondroma are made up of _______ that varies inthickness covered by periochondrium with new bone forming inner portion of head and stalk.

Trabeculae

Woven bone

Hyaline cartillage

14. Are osteochrondroma usually slow or fast growing?

Slow growing

Fast growing

If they impinge on a nerve or a stalk fracture they may be painful.

Explanation

If they impinge on a nerve or a stalk fracture they may be painful.

15. Where do osteochroma usually arise?

Diaphysis

Metaphysis

Epiphysis

16. Do osteochrondromas affect more females or males?

Females

Males

17. Which is greater than 2cm between an osteoid osteoma and an osteoblastoma?

Osteoid osteoma

Osteoblastoma

18. Osteochodroma is also kown as exostosis. True or false?

True

False

19. Looking at an x-ray, if the diagnosis is osteosarcoma, what should one see?

Codman's triangle

Trabeculae of oven bone rimmed with oseoblasts.

Hyalne cartillage covered by periosteum

20. Micro: osteosarcome: pleomorophic and large cells with hyperchromatic nuclei in an osteoid stroma, bizarre tumor giant cells, and mitoses. True or false?

True

False

21. In the microscopic view of osteoid osteoma and osteoblastoma there is a haphzard interconnecting trabecular of won bone riimed by ______ .

Osteoid

Osteoblasts

Osteoclasts

22. Osteosarcoma arise int he metaphysis ad spread along marrow cavities and extend into the epiphysis, do they elevate the periosteum?

Yes

No

23. Osteochondroma usually arise in the metaphysis of the long bones particularly at the ____ .

Hip

Knee

Shoulder

24. The gross structure of osteosarcoma is a bulky, gritty-white tumor with areas of ___ and cystic degeration.

Synovial fluid

Hemmorhage

25. Osteochroma re ______ shaped outgrowths with a cartilage cap attached tothe skeleton by a bony stalk.

Spindle

Mushroom

Sausage

26. Is an osteoblastoma benign or malignant?

Benign

Malignant

27. Basically ES & PNET present as a growing non painful mass. True or false?

True, they are painless

False, they are painful

28. Are endochondromas usually symptomatic?

Yes

No

they are usually found accidentally.

Explanation

they are usually found accidentally.

29. Patients with EW and PNT will most probably undergo which of the following treatment modlities?

Surgery

Chemotherapy

Radiation therapy

Submit

30. Where do ewing sarcoma and PNET usually arise?

Endosteum

Periosteum

Medullary cavity

31. 60% of osteosarcoma occur at the:

Hip

Elbow

Knee

32. What region of tubular bones of the hands and feet is affected by endochondromas?

Metaphyseal

Epiphyseal

Diaphyseal

33. Wht metastastis do 10-20% of osteosarcoma have by the time of diagnosis?

Brain

Breast

Lung

34. Where do osteosarcoma arise?

Epiphysis

Metaphysis

35. The gross structure of endochndroma shows a blue gray transluscent nodule that is greater than or less than 3cm?

>3cm

36. In 60-70% of patients with osteosarcoma what gene is rearranged?

P53

RB

37. Where do osteoblastoma usually occur?

In the face

In the long bones

In the spine

38. What part of the long bones, especially the femur is usually affected by ewing sarcoma or PNET?

Metaphysis

Epiphysis

Diaphysis

39. Which is more painful between an osteoid osteoma and an osteoblastoma?

Osteoid osteoma

Osteoblastoma

due to excess prostaglandin.

Explanation

due to excess prostaglandin.

40. Eswing sarcoma and PNET are small round _______ cell tumors of bone and soft tissue.

Red

Blue

Osteoblast

Osteoid

41. In the elderly osteosarcoma is associated with which of the following?

Paget's disease

Bone infarcts

Irradiation

Submit

42. Which one occurs in the long bones between osteoid osteoma and osteoblastoma?

Osteoid osteoma

Osteoblastoma

43. What age group is usually affected by endochondroma?

10-20

20-30

30-70

20-50

Musculoskeletal Tumors (Msq Drill 148)

1. On X-ray you see a lytic tumor with permeative margins and extension into the soft tissues. True or false?

2.

What first name or nickname would you like us to use?

2. Osteochromas are mosr common in:

3. On x-ray endochondroma is a radioluscent nodule surrounded by a thin rim of bone. True or false?

4. Microscopically endochondroma are lobules or mature hyaline cartilage. True or false?

5. Ewing sarcoma and Primitive Neuroectodermal tumor (PNET) share a common chromosomal translocation and may be viewed as the same tumor with just a difference in neural differentiation. True or false?

6. What is the most frequent malignant bone neoplasm?

7. So, Ewing sarcoma and PNET are benign or malignant?

8. The gross structure of osteoid osteomas and osteoblastoma is: round to oval well circumscribed nidus of hemmorhagic gritty tan tissue surrounded by sclerotic bone. True or flase?

9. Which is more responsive to aspirin between osteoid osteoma and osteoblastoma?

10. Ewing sarcoma and PNET arise in the medullary cavity, do they also invade the cortex and periosteum?

11. Most patients with Ewing sarcoma or PNET are over or under the age of 20?

12. Who is affected more by ewing sarcoma and PNET between males and females?

13. Microscopically osteochondroma are made up of _______ that varies inthickness covered by periochondrium with new bone forming inner portion of head and stalk.

14. Are osteochrondroma usually slow or fast growing?

15. Where do osteochroma usually arise?

16. Do osteochrondromas affect more females or males?

17. Which is greater than 2cm between an osteoid osteoma and an osteoblastoma?

18. Osteochodroma is also kown as exostosis. True or false?

19. Looking at an x-ray, if the diagnosis is osteosarcoma, what should one see?

20. Micro: osteosarcome: pleomorophic and large cells with hyperchromatic nuclei in an osteoid stroma, bizarre tumor giant cells, and mitoses. True or false?

21. In the microscopic view of osteoid osteoma and osteoblastoma there is a haphzard interconnecting trabecular of won bone riimed by ______ .

22. Osteosarcoma arise int he metaphysis ad spread along marrow cavities and extend into the epiphysis, do they elevate the periosteum?

23. Osteochondroma usually arise in the metaphysis of the long bones particularly at the ____ .

24. The gross structure of osteosarcoma is a bulky, gritty-white tumor with areas of ___ and cystic degeration.

25. Osteochroma re ______ shaped outgrowths with a cartilage cap attached tothe skeleton by a bony stalk.

26. Is an osteoblastoma benign or malignant?

27. Basically ES & PNET present as a growing non painful mass. True or false?

28. Are endochondromas usually symptomatic?

29. Patients with EW and PNT will most probably undergo which of the following treatment modlities?

30. Where do ewing sarcoma and PNET usually arise?

31. 60% of osteosarcoma occur at the:

32. What region of tubular bones of the hands and feet is affected by endochondromas?

33. Wht metastastis do 10-20% of osteosarcoma have by the time of diagnosis?

34. Where do osteosarcoma arise?

35. The gross structure of endochndroma shows a blue gray transluscent nodule that is greater than or less than 3cm?

36. In 60-70% of patients with osteosarcoma what gene is rearranged?

37. Where do osteoblastoma usually occur?

38. What part of the long bones, especially the femur is usually affected by ewing sarcoma or PNET?

39. Which is more painful between an osteoid osteoma and an osteoblastoma?

40. Eswing sarcoma and PNET are small round _______ cell tumors of bone and soft tissue.

41. In the elderly osteosarcoma is associated with which of the following?

42. Which one occurs in the long bones between osteoid osteoma and osteoblastoma?

43. What age group is usually affected by endochondroma?