Connective Tissue Diseases (Msq Drill 183)

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  • 1/46 Questions

    Since the exocrine glands are affected will patients with Sjorgren syndrome will have watery or dry eyes?

    • Watery eyes
    • Dry eyes
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  • 2. 

    Sjogren's syndrome is associated with an increased risk of what disease?

    • A

    • B

    • C

    • Lymphoma

    Correct Answer
    A. Lymphoma
  • 3. 

    Systemis sclerosis is also known as _________ .

    • A

    • S

    • D

    • Scleroderma

    Correct Answer
    A. Scleroderma
  • 4. 

    Patients with sclerotic skin changes often accompanied by multisystem disease. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 5. 

    A patient with scleroderma presents to your office complaining of pain in the digitis when they are exposed to cold and a white or bluish color. When rewarmed they trun red before they turn back to the normal color. You determine that this is:

    • A

    • Rreynaud's

    Correct Answer
    A. Rreynaud's
  • 6. 

    Patients with systemic sclerosis or scleroderma may have progressivwe fibrosis from increased deposition of _________________ in interstitium and intima of small alrteries and connective tissues.

    • A

    • Collagen

    Correct Answer
    A. Collagen
  • 7. 

    Does scleroderma have a male or female proponderance?

    • Male

    • Female

    Correct Answer
    A. Female
  • 8. 

    **** Systemic scleroderma patients will have what antibody

    • A

    • Anti SCL- 70

    Correct Answer
    A. Anti SCL- 70
  • 9. 

    Limited scleroderma:

    • A

    • B

    • C

    • Anti-centromere antibody

    Correct Answer
    A. Anti-centromere antibody
  • 10. 

    A rheumatological emergency in scleroderma is:

    • A

    • Scleroderma renal crisis

    Correct Answer
    A. Scleroderma renal crisis
    Explanation
    Creatine level will be elevated and proteinuria

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  • 11. 

    **** What will you treat the patient presenting with a scleroderma renal crisis?

    • A

    • ACE inhibitors

    Correct Answer
    A. ACE inhibitors
  • 12. 

    CTD diseases are ____________ diseases.

    • Uni system

    • Multi system

    Correct Answer
    A. Multi system
  • 13. 

    What is key to the pathegenesis and therapy of CTD's

    • A

    • S

    • Immune mechanisms

    Correct Answer
    A. Immune mechanisms
  • 14. 

    Diagnosis of CTD's is __________ based using criteria.

    • Clinically

    • B

    Correct Answer
    A. Clinically
  • 15. 

    What is the sub serological marker for inflammatory muscle diseases?

    • A

    • Anti-Jo-1

    Correct Answer
    A. Anti-Jo-1
  • 16. 

    If you have SLe, scleroderma and polymyositis then you probably have:

    • A

    • S

    • Mixed connectivce tissue disease

    Correct Answer
    A. Mixed connectivce tissue disease
  • 17. 

    Usually patients with mixed connective tissue diseases will have high titers of:

    • Anti-U1RNP

    • S

    Correct Answer
    A. Anti-U1RNP
  • 18. 

    What do you treat mixed connective tissue diseases with?

    • A

    • High dose steroids

    Correct Answer
    A. High dose steroids
  • 19. 

    Polyarteritis nodosa is a prototype of:

    • A

    • B

    • Vasculitis

    Correct Answer
    A. Vasculitis
  • 20. 

    Necrotizing vasculitis of the upper airways affecting the sinuses, sicus cavity, lower airways and kidneys is known as:

    • Wegener;s granulomatosis

    • B

    Correct Answer
    A. Wegener;s granulomatosis
  • 21. 

    What is the antibody for Wegener's granulomatoma?

    • A

    • S

    • S

    • Antineutrophil cytoplasmic antibody (c-ANCA)

    Correct Answer
    A. Antineutrophil cytoplasmic antibody (c-ANCA)
  • 22. 

    In order to cofirm a diagnosis of Wegener's you need to have a:

    • A

    • D

    • Biopsy

    Correct Answer
    A. Biopsy
  • 23. 

    Polymyositis plus a rash is:

    • A

    • Dermatomyositis

    Correct Answer
    A. Dermatomyositis
  • 24. 

    Is there a variation of scleroderma that is only cutaneous with no systemic involvement?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 25. 

    The antibodies of scleroderma AntiSCL-70 and anti-centromere antibodies do not always have to be present in order for you to make a diagnosis of scleroderma. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 26. 

    Secondary Sjogren syndrome refers to the ______ complex that accompanies any of the connective tissue diseases such as xeropthalmia, keratoconjuctivitis, xerostomia with or without salivary gland enlanrgment.

    • A

    • Sicca

    Correct Answer
    A. Sicca
  • 27. 

    Can SS-A and SS-B also be seen in other CTD's

    • Yes, but they are more specific for Sjogren syndrome

    • No, they will only be seen in Sjogren

    Correct Answer
    A. Yes, but they are more specific for Sjogren syndrome
  • 28. 

    What is the most common connective tissue disease?

    • Sjjorgen syndrome

    • B

    • SLE

    Correct Answer
    A. SLE
    Explanation
    Sjorgren is the second most common CTD.

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  • 29. 

    The immune system destroys what organs in Sjogren's dynsrome?

    • Kidneys

    • Pancreas

    • Endocrine glands

    • Exocrine glands

    Correct Answer
    A. Exocrine glands
  • 30. 

    So the typical patient with scleroderma will present with:

    • Reynaud's phenomenon

    • Edema fingers and hands

    • Skin thickening

    • Visceral manifestation - eg heartburn or gerd (mmost common GI complain), lung, heart, kidneys, & thyroid.

    • Arthralgias and muscle weakness

    Correct Answer(s)
    A. Reynaud's phenomenon
    A. Edema fingers and hands
    A. Skin thickening
    A. Visceral manifestation - eg heartburn or gerd (mmost common GI complain), lung, heart, kidneys, & thyroid.
    A. Arthralgias and muscle weakness
  • 31. 

    Dermatomyositis is an inflammatory muscle disease. Do the patients present with muscle pain or weakness?

    • Pain

    • Weakness

    Correct Answer
    A. Weakness
  • 32. 

    What three modalities are used to treat polymyositis and dermotomyositis?

    • Steroids

    • Methotrexate

    • C

    • Immunosuppressants

    Correct Answer(s)
    A. Steroids
    A. Methotrexate
    A. Immunosuppressants
  • 33. 

    Is Sjogren syndrome a chronic or acute disorder?

    • Chronic

    • Acute

    Correct Answer
    A. Chronic
  • 34. 

    Is Sjogren's more common in men or women?

    • Men

    • Women

    Correct Answer
    A. Women
  • 35. 

    The diganostic ciriteria for Sjorgen's also incudes:

    • Dry eyes > 3 months or use of tear substitutes, or sensation of sand or gravel in eyes

    • Dry mouth > 3 months or swollen salivary glands or frequenst drinking of liquids to help in swallowing

    • Schirmer-I-test or Rose Bengal score

    • Mononuclear cells in glandular tissue

    • Abnormal salivary flow in the salivary glands or parotid gland

    Correct Answer(s)
    A. Dry eyes > 3 months or use of tear substitutes, or sensation of sand or gravel in eyes
    A. Dry mouth > 3 months or swollen salivary glands or frequenst drinking of liquids to help in swallowing
    A. Schirmer-I-test or Rose Bengal score
    A. Mononuclear cells in glandular tissue
    A. Abnormal salivary flow in the salivary glands or parotid gland
  • 36. 

    Do patients with Sjorgens have a high or low titer rheumatoid factor?

    • Low titer

    • High titer

    Correct Answer
    A. Low titer
  • 37. 

    How do you treat Sjogren's syndrome?

    • Saliva substitutes, artificaial tears

    • Increased oral fluid intake

    • Pilocaprine for the eyes to increase tears

    • Antifungals and close dental follow up

    • Same drugs as SLE - hydroxychloroquine, methotrexate and low dose immunosuppressive drugs.

    Correct Answer(s)
    A. Saliva substitutes, artificaial tears
    A. Increased oral fluid intake
    A. Pilocaprine for the eyes to increase tears
    A. Antifungals and close dental follow up
    A. Same drugs as SLE - hydroxychloroquine, methotrexate and low dose immunosuppressive drugs.
  • 38. 

    What is the most common initial complaint of patient with scleroderma?

    • Dysphagia

    • Tight, thin lips with vertical perioral furrows

    • Trismus & transition zone around dental roots

    • Xerostomis, xerophthalmiz

    • Laryngela inolvement with hoarseness

    Correct Answer
    A. Dysphagia
  • 39. 

    Can Sjorgren's affect the parotid gland?

    • Yes, in fact patrotid biopsy is more sensitive and specific

    • No, it does not affect the paroid gland

    Correct Answer
    A. Yes, in fact patrotid biopsy is more sensitive and specific
  • 40. 

    Treatment of scleroderma includes:

    • Same as for SLE - hydrocloroquinone and methotrexate etc..

    • Using gloves and prostaglandian for raynaud's

    • Calcium channel blockers, tropical NTG

    Correct Answer(s)
    A. Same as for SLE - hydrocloroquinone and methotrexate etc..
    A. Using gloves and prostaglandian for raynaud's
    A. Calcium channel blockers, tropical NTG
  • 41. 

    Treatment of connective tissue disease is specific or non-specific

    • Specific

    • Non-specific

    Correct Answer
    A. Non-specific
    Explanation
    Treatment is aimed at specific manifestations of the disease.

    Rate this question:

  • 42. 

    Sjogrens syndrom is divided into primary and secondary. Which of the two is a diagnosis of exclusion?

    • Primary

    • Secondary

    Correct Answer
    A. Primary
  • 43. 

    What antibodies are associated with Sjogren's syndrome?

    • A

    • SS-A

    • B

    • SS-B

    Correct Answer(s)
    A. SS-A
    A. SS-B
  • 44. 

    Patients with polymyositis may present with:

    • Difficulty phonating

    • Nasal regurgitating

    • Aspiration penumonitis

    • Rash

    Correct Answer(s)
    A. Difficulty phonating
    A. Nasal regurgitating
    A. Aspiration penumonitis
    A. Rash
  • 45. 

    Is there an ybony involvement in sclerodactyly of the hands in patients with scleroderma?

    • Yes

    • No

    Correct Answer
    A. No
  • 46. 

    Is sclerodactyly seen in early or late scleroderma?

    • Early

    • Late

    • Both

    Correct Answer
    A. Both

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  • Feb 07, 2019
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