Systemic Lupus Erythematosus (Msq Drill 184)

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  • 1/44 Questions

    Can patients with SLE develop a skin rash after exposure to sunlight?

    • Yes
    • No
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  • 2. 

    Can patients with SLE also have arthritis?

    • No, they never have SLE

    • Yes, but it is not erosive or inflammatory

    Correct Answer
    A. Yes, but it is not erosive or inflammatory
  • 3. 

    Systemic Lupus Erythmatosus is an autoimmune multisystem disease. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 4. 

    In general SLE is more common in men or women?

    • Men

    • Women

    Correct Answer
    A. Women
  • 5. 

    Do we know exactly what causes SLE?

    • Yes

    • No

    Correct Answer
    A. No
  • 6. 

    Are there any neurological disorders associated with SLE?

    • No, there is no CNS involvement

    • Yes, they can have seizures

    Correct Answer
    A. Yes, they can have seizures
  • 7. 

    Patient with SLE can also have new onset psychosis?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 8. 

    Do connective tissue disorders usually isolate themselves to one organ or they usually involve multiple organs?

    • One organ

    • Multiple organs

    Correct Answer
    A. Multiple organs
  • 9. 

    What is the most common presentation of SLE?a

    • Rhabdomyolisis

    • Skin eruptions

    • Seizures

    Correct Answer
    A. Skin eruptions
  • 10. 

    What is the antimalarial drug that is used to treat SLE?

    • Doxycycline

    • Mefloquine

    • Hydroxychloroquine (plaquenil)

    • Primaquine

    Correct Answer
    A. Hydroxychloroquine (plaquenil)
    Explanation
    200mg bid, can cause retinal toxicity, so also have opthalmology exam before starting.

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  • 11. 

    Are there triggers for SLE?

    • Yes. eg UV light and sulfa drugs

    • No, it is an autoimmune disease so there are no triggers.

    Correct Answer
    A. Yes. eg UV light and sulfa drugs
  • 12. 

    What is the main cause of SLE?

    • Photosensitivity

    • Low folic acid

    • Immune complex deposition

    Correct Answer
    A. Immune complex deposition
  • 13. 

    If a patient with lupus has raised patches, adherent keratotic scaline, perifollicular pugging and scarring from older lesions, you would document this as a:

    • Malar rash

    • Discoid rash

    Correct Answer
    A. Discoid rash
    Explanation
    A malar rash is erythematic, flat or raised.

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  • 14. 

    The diagnois of SLE is a clnical diagnosis?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 15. 

    One of the earliest manifestations of patients with SLE with renal inolvment is:

    • Oliguria

    • Foul smelling urine

    • Peristent proteinuria

    Correct Answer
    A. Peristent proteinuria
  • 16. 

    Jacob's arthropathy is:

    • SLE - nonerosive arthritis

    • SLE - erosive arthritis

    Correct Answer
    A. SLE - nonerosive arthritis
  • 17. 

    The butterfly rash seen in SLE is kown as the ________ rash.

    • Malar

    • Atopic

    • Contact dermatitis

    • Lichen planus

    Correct Answer
    A. Malar
  • 18. 

    The basic problem in patients with CTD diseases is the presence of:

    • An elevated ESR

    • An elevated PSA

    • Metastasis

    • Antinuclear antobodies (ANA)

    Correct Answer
    A. Antinuclear antobodies (ANA)
  • 19. 

    The malar rash of SLE spares which part?

    • Temporal area

    • Eyelids

    • Nasolabial folds

    Correct Answer
    A. Nasolabial folds
  • 20. 

    There are 11 criteria for the diagnosis of SLE. In order to diagnose how many criteria out of the 11 do you have to have?

    • 2

    • 3

    • 4

    • 5

    • 6

    Correct Answer
    A. 4
  • 21. 

    Can hair dyes and lipstick cause SLE?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 22. 

    SLE patients can also have oral or nasopharyngeal ulcers. Are these painful or painless?

    • Painful

    • Painless

    Correct Answer
    A. Painless
  • 23. 

    The larynx and trachea can also be nvolved in patients with SLE. Is this common or uncommon?

    • Common

    • Uncommon

    Correct Answer
    A. Uncommon
  • 24. 

    The prevalence of antinuclear antibodies in women is about 1 in every  ______ women.

    • 50

    • 100

    • 1000

    • 10 000

    Correct Answer
    A. 1000
  • 25. 

    Which of the following are also presentations that can be seen in patients with SLE?

    • Photosensitive skin eruptions

    • Serositis

    • Pneumonitis

    • Myocarditis & nephritis

    • CNS involvement

    Correct Answer(s)
    A. Photosensitive skin eruptions
    A. Serositis
    A. Pneumonitis
    A. Myocarditis & nephritis
    A. CNS involvement
  • 26. 

    Which common symptoms are shared by most connective tissue diseases?

    • General systemis features such as malaise, fever or weight loss

    • Evidence of multiple organ system involvement

    • Musculoskeletal involvement-arthritis, myalgia

    • Immune alterations that leads to pathologic inflammation

    Correct Answer(s)
    A. General systemis features such as malaise, fever or weight loss
    A. Evidence of multiple organ system involvement
    A. Musculoskeletal involvement-arthritis, myalgia
    A. Immune alterations that leads to pathologic inflammation
  • 27. 

    A positive ANA means a patient has LUPUS?

    • Yes

    • No

    Correct Answer
    A. No
    Explanation
    Lupus is a clinical diagnosis, you have to correlate the positive ANA to the clinical symptoms.

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  • 28. 

    Is SLE more common in white or black populations?

    • White

    • Black

    Correct Answer
    A. White
  • 29. 

    Is the deformitiy seen in SLE nonerosive arthiritis reversible?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 30. 

    A patient cannot be diagnosed with a CTD in the absence od antinuclear antibodies. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 31. 

    Which of the following diseases are examples of connective tissue diseases?

    • SLE & RA

    • Mixed connective tissue disease

    • Sjorgrens Syndrome & systemic sclerosis

    • Diabetes

    • Polymyositis/dermatomyositis

    Correct Answer(s)
    A. SLE & RA
    A. Mixed connective tissue disease
    A. Sjorgrens Syndrome & systemic sclerosis
    A. Polymyositis/dermatomyositis
  • 32. 

    Anti-histone antibody is a sub serologic test goes along with:

    • Systemis lupus

    • Rheumatoid arthritis

    • Osteoporosis

    • Drug induced lupus

    Correct Answer
    A. Drug induced lupus
  • 33. 

    About _____ % of patients with antinuclear antibodies will NOT have a CTD?

    • 2

    • 3

    • 5

    • 15

    • 25

    Correct Answer
    A. 5
  • 34. 

    UV light & sulfa driugs are definite, probable or possible cause of lupus?

    • Definite

    • Probable

    • Possible

    Correct Answer
    A. Definite
  • 35. 

    What other medications can be used in the treatment of SLE?

    • Low dose methotrexate

    • Aziothioprine (imuran)

    • Cyclophsophamide

    • High dose steroid for serious visceral involvement

    • Topical and low dose steroids and NSAIDS

    Correct Answer(s)
    A. Low dose methotrexate
    A. Aziothioprine (imuran)
    A. Cyclophsophamide
    A. High dose steroid for serious visceral involvement
    A. Topical and low dose steroids and NSAIDS
  • 36. 

    So, if 1000 women are tested and 51 are ANA positive, about how many of these 51 women will have Systemic lupus erythmatosus?

    • 1

    • 5

    • 15

    • 25

    Correct Answer
    A. 1
  • 37. 

    What percentage of patients with SLE have ANAs?

    • 50%

    • 75%

    • 99%

    • 100%

    Correct Answer
    A. 99%
    Explanation
    ANA's antinuclear antibodies

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  • 38. 

    What is the peak age of the onset for SLE?

    • 15-25

    • 5-15

    • 18-36

    • 30-55

    Correct Answer
    A. 15-25
  • 39. 

    Does an ANA negative lupus exist?

    • Yes

    • No

    Correct Answer
    A. No
  • 40. 

    Which of the following tests specifically go along with SLE.

    • Positive ANA

    • Antibodies to ds-DNA

    • Antibodies to Smith antibody

    • Anticardiolipin antibodies

    • IgM or IgG, leukopenia, anemia

    Correct Answer(s)
    A. Positive ANA
    A. Antibodies to ds-DNA
    A. Antibodies to Smith antibody
    A. Anticardiolipin antibodies
    A. IgM or IgG, leukopenia, anemia
  • 41. 

    The immune system basically attacks the body in connective tissue dieases. True or false?

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Self directed immune mechanisms.

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  • 42. 

    Drug induced Lupus can be caused by the following drugs:

    • Hydralazine

    • Loperamide

    • Procainamide

    • Hydrochlorothiazide

    Correct Answer(s)
    A. Hydralazine
    A. Procainamide
  • 43. 

    Although rare - What are the three most common life threatening consequences of SLE?

    • Nephritis

    • Respiratory depression

    • Thrombocytopenia

    • Cerebritis

    Correct Answer(s)
    A. Nephritis
    A. Thrombocytopenia
    A. Cerebritis
  • 44. 

    What would you tell you patient who has lupus?

    • Avoid the sun

    • Use suncscreen

    • Postprandal rinse or hydrogen peroxide

    • Use salivary substitutes

    • Lower your fluid intake

    Correct Answer(s)
    A. Avoid the sun
    A. Use suncscreen
    A. Postprandal rinse or hydrogen peroxide
    A. Use salivary substitutes

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  • Feb 16, 2019
    Quiz Edited by
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