Chapter 17

29 Questions  I  By KaliCox
Chapter 17

  
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1.  What is the correct order of function of the following enzymes of (beta) oxidation? 1. Beta-Hydroxyacyl-CoA dehydrogenase 2. Thiolase 3. Enoyl-CoA hydratase 4. Acyl-CoA dehydrogenase
A.
B.
C.
D.
E.
2.  Lipoprotein lipase acts in:
A.
B.
C.
D.
E.
3.  Transport of fatty acids from the cytoplasm to the mitochondrial matrix requires:
A.
B.
C.
D.
E.
4.  During  oxidation of fatty acids, ___________ is produced in peroxisomes but not in mitochondria.
A.
B.
C.
D.
E.
5.  The role of hormone-sensitive triacylglycerol lipase is to:
A.
B.
C.
D.
E.
6.  Complete oxidation of 1 mole of which fatty acid would yield the most ATP?
A.
B.
C.
D.
E.
7.  Ketone bodies are formed in the liver and transported to the extrahepatic tissues mainly as:
A.
B.
C.
D.
E.
8.  Which of the following statements apply (applies) to the betaWhich of the following statements apply (applies) to the beta oxidation of fatty acids? 1. The process takes place in the cytosol of mammalian cells. 2. Carbon atoms are removed from the acyl chain one at a time. 3. Before oxidation, fatty acids must be converted to their CoA derivatives. 4. NADP+ is the electron acceptor. 5. The products of beta oxidation can directly enter the citric acid cycle for further oxidation.  oxidation of fatty acids?
A.
B.
C.
D.
E.
9.  Free fatty acids in the bloodstream are:
A.
B.
C.
D.
E.
10.  Which of the following is (are) true of the oxidation of 1 mol of palmitate (a 16-carbon saturated fatty acid; 16:0) by the beta-oxidation pathway, beginning with the free fatty acid in the cytoplasm? 1. Activation of the free fatty acid requires the equivalent of two ATPs. 2. Inorganic pyrophosphate (PPi) is produced. 3. Carnitine functions as an electron acceptor. 4. 8 mol of FADH2 are formed. 5. 8 mol of acetyl-CoA are formed. 6. There is no direct involvement of NAD+.
A.
B.
C.
D.
E.
11.  The balanced equation for the degradation of CH3(CH2)10COOH via the beta-oxidation pathway is:
A.
B.
C.
D.
12.  The glycerol produced from the hydrolysis of triacylglycerides enters glycolysis as:
A.
B.
C.
D.
E.
13.  Carnitine is:
A.
B.
C.
D.
E.
14.  The carbon atoms from a fatty acid with an odd number of carbons will enter the citric acid cycle as acetyl-CoA and:
A.
B.
C.
D.
E.
15.  The conversion of palmitoyl-CoA (16:0) to myristoyl-CoA (14:0) and 1 mol of acetyl-CoA by the -oxidation pathway results in the net formation of:
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B.
C.
D.
E.
16.  Which enzyme is the major regulatory control point for -oxidation?
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B.
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D.
E.
17.  Fatty acids are activated to acyl-CoAs and the acyl group is further transferred to carnitine because:
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B.
C.
D.
E.
18.  When comparing the B-oxidation and W-oxidation pathways, which one of the following statements is correct?
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B.
C.
D.
E.
19.  The major site of formation of acetoacetate from fatty acids is the:
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B.
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D.
E.
20.  Which of the following statements concerning the beta oxidation of fatty acids is true?
A.
B.
C.
D.
E.
21.  Which of these is able to cross the inner mitochondrial membrane?
A.
B.
C.
D.
E.
22.  Which of the following is (are) true of the  oxidation of long-chain fatty acids? 1. The enzyme complex that catalyzes the reaction contains biotin. 2. FADH2 serves as an electron carrier. 3. NADH serves as an electron carrier. 4. Oxidation of an 18-carbon fatty acid produces six molecules of propionyl-CoA. 5. Oxidation of a 15-carbon fatty acid produces at least one propionyl-CoA.
A.
B.
C.
D.
E.
23.  In the disease sprue, vitamin B12 (cobalamin) is poorly absorbed in the intestine, resulting in B12 deficiency. If each of the following fatty acids were in the diet, for which one would the process of fatty acid oxidation be most affected in a patient with sprue?
A.
B.
C.
D.
E.
24.  Saturated fatty acids are degraded by the stepwise reactions of  beta oxidation, producing acetyl-CoA. Under aerobic conditions, how many ATP molecules would be produced as a consequence of removal of each acetyl-CoA?
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B.
C.
D.
E.
25.  If an aerobic organism (e.g., the bacterium E. coli) were fed each of the following four compounds as a source of energy, the energy yield per mole from these molecules would be in the order:
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B.
C.
D.
E.
26.  Which of the following is not true regarding the oxidation of 1 mol of palmitate (16:0) by the -oxidation pathway?
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B.
C.
D.
E.
27.  The following fatty acid, in which the indicated carbon is labeled with 14C, is fed to an animal: 14CH3(CH2)9COOH After allowing 30 minutes for fatty acid  oxidation, the label would most likely be recovered in:
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B.
C.
D.
E.
28.  Which compound is an intermediate of the beta oxidation of fatty acids?
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B.
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D.
E.
29.  If the 16-carbon saturated fatty acid palmitate is oxidized completely to carbon dioxide and water (via the Beta-oxidation pathway and the citric acid cycle), and all of the energy-conserving products are used to drive ATP synthesis in the mitochondrion, the net yield of ATP per molecule of palmitate is:
A.
B.
C.
D.
E.
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