Unlock your full potential and guarantee your success on the ANCC and AANP certification exams! You won't just study; you'll master the content, building the unshakeable confidence needed to pass and become certified. PMHNP certification exam prep materials are developed and peer-reviewed by subject-matter experts with advanced education and certified in the specialty.

5 Sample Questions

Which neurotransmitter is most directly involved in long-term potentiation (LTP) in the hippocampus?

  • A. GABA
  • B. Dopamine
  • C. Glutamate (NMDA receptor)
  • D. Serotonin

A drug with a high volume of distribution (Vd) is most likely:

  • A. Confined to the vascular compartment
  • B. Highly protein-bound in plasma
  • C. Lipophilic and extensively distributed into tissues
  • D. Primarily excreted unchanged in urine

Cytochrome P450 2D6 poor metabolizers will have elevated plasma levels of which antidepressant?

  • A. Sertraline
  • B. Nortriptyline
  • C. Venlafaxine
  • D. Bupropion

Which ion channel alteration underlies the action potential plateau in cardiac myocytes?

  • A. Increased Na conductance
  • B. Transient K⁺ efflux
  • C. L-type Ca²⁺ influx
  • D. Cl influx

The half life of a medication is most directly proportional to:

  • A. Clearance
  • B. Volume of distribution 
  • C. Bioavailability
  • D. Protein binding

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