Genetics Hardest Test! Quiz Questions! Trivia
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Do you have enough knowledge to pass these genetics hardest test quiz questions? Two people share almost all their genetic material with a 0.1 difference when analyzed in most cases, and as a genetics student, it is important to know what makes one person’s DNA different from the other. Test out your understanding when it comes to genes by taking this exciting quiz, feel free to take it as many times s possible.
- 1.
The product of gene expression can be ___________ in many of the steps before gene assembly / conformation.
- 2.
RNA Polymerase I is...
- A.
Inhibited by a-amanitin
- B.
Only inhibited by small amounts of a-amanitin
- C.
Only inhibited by large amounts of a-amanitin
- D.
Insensitive to a-amanitin
Correct Answer
D. Insensitive to a-amanitin -
- 3.
RNA Polymerase II is...
- A.
Inhibited by a-amanitin
- B.
Only inhibited by small amounts of a-amanitin
- C.
Only inhibited by large amounts of a-amanitin
- D.
Insensitive to a-amanitin
Correct Answer
A. Inhibited by a-amanitin -
- 4.
RNA Polymerase III is...
- A.
Inhibited by a-amanitin
- B.
Only inhibited by small amounts of a-amanitin
- C.
Only inhibited by large amounts of a-amanitin
- D.
Insensitive to a-amanitin
Correct Answer
C. Only inhibited by large amounts of a-amanitin -
- 5.
RNA Polymerase I synthesises
- A.
Ribosomal RNA (rRNA)
- B.
Messenger RNA (mRNA)
- C.
Transport RNA (tRNA
Correct Answer
A. Ribosomal RNA (rRNA) -
- 6.
RNA Polymerase II synthesises
- A.
Ribosomal RNA (rRNA)
- B.
Messenger RNA (mRNA)
- C.
Transport RNA (tRNA
Correct Answer
B. Messenger RNA (mRNA) -
- 7.
RNA Polymerase III synthesises
- A.
Ribosomal RNA (rRNA)
- B.
Messenger RNA (mRNA)
- C.
Transport RNA (tRNA
Correct Answer
C. Transport RNA (tRNA -
- 8.
The 5s ribosome subunit is synthesised by which RNA polymerase?
- A.
RNAP I
- B.
RNAP II
- C.
RNAP III
Correct Answer
C. RNAP III -
- 9.
Roeder discovered RNA polymerase through experiments with which eukaryotic organism?______________
Correct Answer
sea urchins
urchins - 10.
Chambon discovered RNA polymerase through experiments with which eukaryotic organism?_______________
Correct Answer
Yeast
yeasts - 11.
Chambon and Roeder discovered the three RNA polymerases through which experimental technique?_________________
Correct Answer
Column chromatography - 12.
RNA polymerase has been _____________ through evolution.
Correct Answer
conserved - 13.
The subunits beta and beta' are
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
A. The large subunits of bacterial polymerase -
- 14.
The subunits alpha I and alpha II are
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
B. The small subunits of bacterial polymerase -
- 15.
The subunits RPB1 and RPB2 are
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
C. The large subunits of yeast polymerase -
- 16.
The subunits RPB3 and RPB11 are
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
D. The small subunits of yeast polymerase -
- 17.
The subunits RPB3 and RPB11 are comparable to
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
B. The small subunits of bacterial polymerase -
- 18.
The subunits RPB1 and RPB2 are comparable to
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
A. The large subunits of bacterial polymerase -
- 19.
The subunits beta and beta' are comparable to
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
C. The large subunits of yeast polymerase -
- 20.
The subunits alpha I and alpha II are comparable to
- A.
The large subunits of bacterial polymerase
- B.
The small subunits of bacterial polymerase
- C.
The large subunits of yeast polymerase
- D.
The small subunits of yeast polymerase
Correct Answer
D. The small subunits of yeast polymerase -
- 21.
How are eukaryotic polymerases different from bacterial polymerases.
- 22.
RNA polymerase II has ___ subunits
Correct Answer
12
twelve - 23.
RNA polymerase II has a unique domain called the ___________________________
Correct Answer
CTD
Carboxy terminal domain - 24.
The carboxy terminal domain is a sequence of tandem repeats
- A.
True
- B.
False
Correct Answer
A. True -
- 25.
The carboxy terminal domain is phosphorylated under default in vivo conditions
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
The CTD is phosphorylated during transcriptionRate this question:
-
- 26.
How many tandem repeats in the CTD of RNAPII in yeast?
- 27.
How many tandem repeats in the CTD of RNAPII in humans?
- 28.
How many tandem repeats in the CTD of RNAPII in drosophila?
- 29.
What happens if half of all the tandem repeats of a CTD are removed?
- 30.
Condensed genes are ____________ by histones.
Correct Answer
repressed - 31.
In order to decondense genes, an ________ must be recruited, which forms a large protein complex.
Correct Answer
activator - 32.
The large complex of proteins involoved in decondensation of the nucleosomes include
- A.
General transcription factors
- B.
RNAPII
- C.
Mediator
Correct Answer(s)
A. General transcription factors
B. RNAPII
C. Mediator -
- 33.
The ___________ forms a molecular bridge between activation domains and RNAPII
Correct Answer(s)
Mediator - 34.
The TATA box, Initiator element and Downstream promoter element make up the
- A.
Enhancer
- B.
Core promoter
- C.
Proximal promoter element
Correct Answer
B. Core promoter -
- 35.
Where are 'Enhancers' located?
- 36.
Where are 'Proximal promoter elements' located?
- 37.
Which transcription factor bends the DNA at the TATA box?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
B. TFIID -
- 38.
Which transcription factor attaches to TFIID?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
A. TFIIB -
- 39.
Which transcription factor forms a complex with RNAP II?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
D. TFIIF -
- 40.
Which transcription factor forms a complex with RNAP II and attaches to the TF complex at the TATA site?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
D. TFIIF -
- 41.
Which transcription factor attaches to the large TF and RNAP II complex at the TATA site?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
C. TFIIE -
- 42.
Which transcription factor is the last to attach to the protein complex and initiates translation?
- A.
TFIIB
- B.
TFIID
- C.
TFIIE
- D.
TFIIF
- E.
TFIIH
Correct Answer
E. TFIIH -
- 43.
TFIIH uses its helicase ability to unwind DNA at the START codon by using energy from ATP hydrolysis.
- A.
True
- B.
False
Correct Answer
A. True -
- 44.
Activators contain...
- A.
1 DNA binding domain and 1 activation domain
- B.
At least one DNA binding domain and 1 activation domain
- C.
1 DNA binding domain and at least one activation domain
Correct Answer
C. 1 DNA binding domain and at least one activation domain -
- 45.
Activators bind to
- A.
Enhancers
- B.
TATA box
- C.
Core promoter
- D.
Proximal-promoter element
Correct Answer(s)
A. Enhancers
D. Proximal-promoter element -
- 46.
The process in which two unrelated transcription factors bind cooperatively is called _____________
Correct Answer(s)
cooperative binding - 47.
Pull down assays have been used to prove protein-protein interactions. Such as...
- A.
GST-TFIIB binds GAL4-VP16
- B.
GST-TFIIB binds GAL4
- C.
GST binds GAL4-VP16
- D.
GST binds GAL4
Correct Answer
A. GST-TFIIB binds GAL4-VP16 -
- 48.
Activator proteins overcome the "steric" hindrance of nucleosomes by two methods. Namely...
Correct Answer
Remodelling and modification
Modification and remodelling - 49.
The following is the method of which process, commonly employed by activators..."Histones covalently modified by co-activators such as HATS"
- A.
Remodelling
- B.
Modification
Correct Answer
B. Modification -
- 50.
The following is the method of which process, commonly employed by activators..."Co-activators move nucleosomes on the DNA template"
- A.
Remodelling
- B.
Modification
Correct Answer
A. Remodelling -
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-
Current Version
-
Mar 21, 2022Quiz Edited by
ProProfs Editorial Team -
Feb 20, 2011Quiz Created by
Alanmahon
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