Cell Signalling

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Esignalling within and between cells is essentail for many biological processes.

Questions and Answers

1.

The three classes of signalling are (select 3)
- A.
  
  Endocrine
- B.
  
  Emdocrine
- C.
  
  Parocrine
- D.
  
  Autocrine
- E.
  
  Paracrine
Correct Answer(s)
A. Endocrine
D. Autocrine
E. Paracrine

Explanation
endocrine - long range signalling
paracride - local signalling
autocrine - same cell signalling

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2.

Dinsulin is a
- A.
  
  Peptide hormone
- B.
  
  Small water soluble molecule
- C.
  
  Lipophilic molecule which is detected by a cell surface receptor
- D.
  
  Lipophilic molecule which is detected by a intracellular receptor
- E.
  
  Kinase
Correct Answer
A. Peptide hormone

Explanation
peptide hormones are water soluble and carried to their site of action by the vascular system. another peptide hormone is glucagon

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3.

The receptor that is activated by binding to a ligand which results in the activation of a g protein which conveys the message to the next component in the signalling pathway

Correct Answer
G protein linked receptor
G-protein linked receptor
G protein-linked receptor
g protein linked receptor
G protein coupled receptor

Explanation
G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR),

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4.

G proteins
- A.
  
  Are composed of 4 subunits
- B.
  
  Activate adenyla cyclasie
- C.
  
  Activate the cell cycle
- D.
  
  Are invloved in the production of cAMP
Correct Answer
D. Are invloved in the production of cAMP
5.

.............. is the process where receptors move to a site of invagination and then a vacuole is formed, aided by the presence of clathrin molecules.

Correct Answer
endocytosis
Endocytosis
6.

A futile cycle
- A.
  
  Is when production become over production
- B.
  
  Is when the compound being produced is fertilized
- C.
  
  Is when the compound being produced is being broken down at the same time
- D.
  
  Is when a compound is being broken down faster then its being produced
- E.
  
  Is when the compund is getting dephosphorylated
Correct Answer
C. Is when the compound being produced is being broken down at the same time
7.

PKC stands for

Correct Answer
Protein Kinase C
protein kinase c
protein kinase C
8.

CAMP is (select 2)
- A.
  
  A first messenger
- B.
  
  A second messenger
- C.
  
  Produced in the plasma membrane by adenlyly cyclase
- D.
  
  Aka cyalinc AMP
- E.
  
  A g protein-linked receptor
Correct Answer(s)
B. A second messenger
C. Produced in the plasma membrane by adenlyly cyclase
9.

PtdInsP2 is broken down by ........ to give Ip3 and DAG

Correct Answer(s)
Phospholipase C
phospholipase c
phospholipase C
10.

Which is a protein that isnt controlled by calcium ion concentrations??
- A.
  
  Adenylyl cyclase
- B.
  
  Troponin
- C.
  
  Tyrosine cyclase
- D.
  
  Pyruvate dehydrogenase
- E.
  
  Protein kinase c
Correct Answer
C. Tyrosine cyclase
11.

Calmodulin has ... Ca2+ binding sites
- A.
  
  2
- B.
  
  1
- C.
  
  3
- D.
  
  5
- E.
  
  4
Correct Answer
E. 4
12.

All of the following are a cellular effect induced by .............1. activation of RAS2. phosphorylation of kinases3. regulation of gene expression4. modulation of protein synthesis5. phosphorylation of IRS-16. production of glucagon

Correct Answer
insulin
Insulin
13.

Which is incorrect about insulin
- A.
  
  It has 2 disulphide bonds
- B.
  
  The n-terminal and c-terminal ends of the B chain reach out into solution
- C.
  
  A chain has 21 amino acids
- D.
  
  B chain has 30 amino acids
- E.
  
  Its produced by the cells of the islets of langerhans
Correct Answer
A. It has 2 disulphide bonds
14.

Yes or no - binding of insulin to its receptor results in dephosphorylation of the receptor on tyrosine residues

Correct Answer
no
No

Explanation
it results in autophosphorylation

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15.

Which is incorrect about rods and cones
- A.
  
  They are single cells
- B.
  
  They contain up to 1000 discs in their outer segment
- C.
  
  They are bipolar - inner and outer segment
- D.
  
  They contain chloroplasts
- E.
  
  They contain mitochondria
Correct Answer
D. They contain chloroplasts
16.

A protein comprised of a polypeptide called opsin and a non-protein part called 11-cis-retinal?

Correct Answer
rhodospin
Rhodopsin
17.

Apoptosis isnt
- A.
  
  Cell death
- B.
  
  Cell suicide
- C.
  
  Programmed cell death
- D.
  
  Proliferation
Correct Answer
D. Proliferation

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Current Version
Jan 15, 2013

Quiz Edited by
ProProfs Editorial Team
Jun 18, 2010

Quiz Created by
Havnell88

Cell Signalling

The three classes of signalling are (select 3)

Dinsulin is a

The receptor that is activated by binding to a ligand which results in the activation of a g protein which conveys the message to the next component in the signalling pathway

G proteins

.............. is the process where receptors move to a site of invagination and then a vacuole is formed, aided by the presence of clathrin molecules.

A futile cycle

PKC stands for

CAMP is (select 2)

PtdInsP2 is broken down by ........ to give Ip3 and DAG

Which is a protein that isnt controlled by calcium ion concentrations??

Calmodulin has ... Ca2+ binding sites

All of the following are a cellular effect induced by .............1. activation of RAS2. phosphorylation of kinases3. regulation of gene expression4. modulation of protein synthesis5. phosphorylation of IRS-16. production of glucagon

Which is incorrect about insulin

Yes or no - binding of insulin to its receptor results in dephosphorylation of the receptor on tyrosine residues

Which is incorrect about rods and cones

A protein comprised of a polypeptide called opsin and a non-protein part called 11-cis-retinal?

Apoptosis isnt