CVS Test For Detailers 12 October 2011
Testing knowledge about Losartan and Losartan Co market and cycle 4's market strategy.
- 1.Which product is currently market leader in total ARB/HCTZ market?
- A.
Fortzaar
- B.
Co-Diovan
- C.
Co-Tareg
- D.
Atacand Plus
- E.
Co-Pritor
- 2.How big is the combined Losartan/HCTZ market?
- A.
R20m
- B.
R23,5m
- C.
R19,4m
- D.
R33,5m
- 3.Which ARB/HCTZ product is the fastest growing product in the ARB/HCTZ market?
- A.
Co-Diovan
- B.
Fortzaar
- C.
Co-Tareg
- D.
Atacand Plus
- E.
Co-Pritor
- 4.What percentage of the Losartan/HCTZ market is still held by the originators?
- A.
50%
- B.
84%
- C.
73%
- D.
96%
- E.
100%
- 5.Name the first losartan/HCTZ generic
- A.
Fortzaar
- B.
Sartoc
- C.
Lozaan Co
- D.
Co-Pritor
- 6.Who manufactures the first losartan/HCTZ generic?
- A.
MSD
- B.
Accord
- C.
Aspen
- D.
Sandoz
- E.
Winthrop
- 7.The main shortcoming of the first losartan/HCTZ was that it was presented in 50/25 mg strength.
- A.
True
- B.
False
- 8.Name the Akacia losartan/HCTZ generic
- A.
Lozaan Co
- B.
Losaar Plus
- C.
Fortzaar
- D.
Co-Pritor
- 9.Name the Ranbaxy losartan/HCTZ generic
- A.
Fortzaar
- B.
Lohype Plus
- C.
Lozaan Co
- D.
Losaar Plus
- 10.Which losartan/HCTZ strength is the biggest selling SKU? ........./.........mg
- A.
100/25mg
- B.
50/12,5mg
- C.
50/25mg
- D.
80/12,5mg
- 11.Name the other or competitor losartan/HCTZ generic brand that also has a plain losartan range
- A.
Cipla- Losartan
- B.
Atacand
- C.
Lozaan
- D.
Sartoc
- E.
None of that is mentioned here
- F.
Zartan
- 12.One feature that is unique to losartan, is that it is particularly helpful to patients who suffer from gout, because it reduces the mineral acid levels in the body
- A.
True
- B.
False
- 13.The type of hypertension that is often seen in elderly patients and is characterized by a large difference between systolic and diastolic blood pressure is called isolated diastolic hypertension.
- A.
True
- B.
False
- 14.What combination therapy would be a similar but more affordable option from Pharma Dynamics for doctors wishing to prescribe Exforge? Answer:
- Zartan Co and Amloc / PD Amlodipene
- A.
True
- B.
False
- 15.The maximum cost saving % between ZARTAN CO and the most affordable telmisartan/HCTZ combination is 32%?
- A.
True
- B.
False
- 16.Name the product that is market leader in the plain losartan market .
- A.
Cozaar
- B.
Cipla-Losartan
- C.
Zartan
- D.
Diovan
- E.
Spec-Losartan
- 17.How many patients overall were recruited in the CONFIDENCE study?
- A.
666
- B.
3800
- C.
8300
- D.
1300
- E.
Non of the above
- 18.In which year was The CONFIDENCE study published in the American Journal of Cardiovascular Drugs?
- A.
2008
- B.
2009
- C.
2010
- D.
2011
- 19.Which of the following subpopulations were NOT monitored in the CONFIDENCE study?
- A.
Diabetic population
- B.
Metabolic syndrome population
- C.
Asian population
- D.
Severe hypertensive population
- 20.The authors of the CONFIDENCE study concluded the following
- A.
Perindopril 4-8 mg/day is a dose dependant, effective, and well tolerated antihypertensive treatment
- B.
Perindopril 8 mg significantly lowered BP in severely hypertensive patients
- C.
Uptitration to the optimum dose of perindopril may be considered as an effective approach for the management of hypertension, and conferring the benefits of outcome studies
- D.
All of the above
- 21.In the CONFIDENCE study, 193 of the severely hypertensive patients were titrated up to perindopril 8mg. What was the BP lowering observed after 12 weeks?
- A.
10.1/5.4 mmHg
- B.
18.9/9.7 mmHg
- C.
23.1/9.0 mmHg
- D.
37.6/15.3 mmHg
- 22.Perindopril tert-butylamine 8 mg and perindopril arginine 10 mg are both equivalent to the following quantity of active base
- A.
6.7 mg
- B.
7.6 mg
- C.
8.0 mg
- D.
10.0 mg
- 23.The AUC ratio for perindoprilat from perindopril tert-butylamine 8 mg and perindopril arginine 10 mg was found to be?
- A.
80%
- B.
90%
- C.
69.3%
- D.
100%
- 24.Perindopril tert-butylamine 8 mg and perindopril arginine 10 mg were found to be
- A.
Therapeutically equivalent in terms of BP lowering
- B.
Interchangable
- C.
Substitutable
- D.
All of the above
- 25.What is the IMS MAT Rand value of the perindopril plain market?
- A.
R13 million
- B.
R65 million
- C.
R100 million
- D.
R130 million
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