Sppu-pet pH.d Entrance Mock Test No.1-paper II (developed By Dr. Anwar Shaikh)

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SPPU-PET Ph. D Entrance Mock Test No. 1-Paper IITotal Question: 50, Duration: 30 MinutesPassing Criteria: 50 %Total Marks: 50


Questions and Answers
  • 1. 
    The following gibberalin derivative is known as gibberalic acid………
    • A. 

      GA1

    • B. 

      GA2

    • C. 

      GA3

    • D. 

      GA4

  • 2. 
    The following is the precursor for the synthesis of Dhurrin in sikkimic acid pathway…………..
    • A. 

      Phenylalanine

    • B. 

      Tyrosine

    • C. 

      Linamarin

    • D. 

      Lotuustralin

  • 3. 
    Multicellular branched covering peltate trichomes are characteristic for…………..
    • A. 

      Hammelis

    • B. 

      Humulus

    • C. 

      Verbascum Thapsus

    • D. 

      All of the above

  • 4. 
    Ranunculaceous stomata is the characteristic for ……..
    • A. 

      Buchu

    • B. 

      Digitalis

    • C. 

      Lobelia

    • D. 

      All of the above

  • 5. 
    Moisture content limit for digitalis should not be more than……
    • A. 

      10

    • B. 

      05

    • C. 

      08

    • D. 

      15

  • 6. 
    The fluorescence exhibited by rhubarb under UV light is…………….
    • A. 

      Purple blue

    • B. 

      Whitish blue

    • C. 

      Viloet

    • D. 

      Mauve

  • 7. 
    For the measurement of hypoglycemic activity, the following herbal extract is used…………..
    • A. 

      Karela

    • B. 

      Jambul

    • C. 

      Fenugreek

    • D. 

      All of the above

  • 8. 
    The total aerobic microbial load per gram of material ready for internal use is………….
    • A. 

      105

    • B. 

      102

    • C. 

      10

    • D. 

      103

  • 9. 
    Outgrowth arista( awn) is found in following drug……
    • A. 

      Cardamom

    • B. 

      Castor

    • C. 

      Nutmeg

    • D. 

      Stropanthus

  • 10. 
    The cathartic principle in momordica charantia is…….
    • A. 

      Charantin

    • B. 

      Momordicin

    • C. 

      Saponin

    • D. 

      Glucoside

  • 11. 
    The IUPAC name for Prazepam is……
    • A. 

      7-chloro-1-methyl-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one

    • B. 

      8-chloro-1-( Cyclobutylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one

    • C. 

      7-chloro-1-( Cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one

    • D. 

      8-chloro-1-( Cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-benzodiazepine-2-one

  • 12. 
    Buspirone contain following ring system……….
    • A. 

      Spiran

    • B. 

      Piperazine

    • C. 

      Pyrimidine

    • D. 

      All of the above

  • 13. 
    4-[3-[2-( trisfluoromethyl) phenazin-10-yl]propyl]-1-piperazineethanol tends for……………..
    • A. 

      Perphenazine

    • B. 

      Fluphenazine

    • C. 

      Acetophenazine

    • D. 

      Trifluoperazine

  • 14. 
    6-[ 2,3-dichloro phenyl)]-3,5-diamino triazine tends for following category of drug……………..
    • A. 

      Anti-depressant

    • B. 

      Anti-psychotic

    • C. 

      Anxiolytic drug

    • D. 

      Anti-epileptic drug

  • 15. 
    The following is CNS stimulant drug…..
    • A. 

      Mazindol

    • B. 

      Phendimetrazine

    • C. 

      Pemoline

    • D. 

      All of above All of the above

  • 16. 
    The tricyclic anti-depressant drug trazodone contain following ring system…………
    • A. 

      Piperazine

    • B. 

      Triazole

    • C. 

      Pyridine

    • D. 

      All of the above All of the above

  • 17. 
    The following is true for dobutamine except….
    • A. 

      B1- receptor agonist

    • B. 

      It is used in cardiogenic shock

    • C. 

      (-) enantiomer is potent α1 agonist

    • D. 

      (-) enantiomer is potent α2 agonist

  • 18. 
    The mechanism of corynanthine is……………
    • A. 

      Selective α2 receptor antagonist

    • B. 

      Selective α1 receptor antagonist

    • C. 

      Non-selective α receptor antagonist

    • D. 

      Selective β1-receptor agonist

  • 19. 
    Occulomucocutaneous syndrome is the side effect of following drug……
    • A. 

      Metoprolol

    • B. 

      Practolol

    • C. 

      Albuterol

    • D. 

      Atenolol

  • 20. 
    The following drug is safe in hypertension in pragnency ……………
    • A. 

      Methyl dopa

    • B. 

      Labeatalol

    • C. 

      Carvediol

    • D. 

      Ritodrine

  • 21. 
    To filter the slurries containing the solids not more than 5 %, the following filter is used………..
    • A. 

      Filterpress

    • B. 

      Filterleaf

    • C. 

      Meta fliter

    • D. 

      Membrane filter

  • 22. 
    If carr’s index is 23-35 then flow is ……………
    • A. 

      Excellent

    • B. 

      Fair to passable

    • C. 

      Poor

    • D. 

      Extremely poor

  • 23. 
    If the PKa of Phenobarbitone is 7.4.what fraction of drug would be ionized at pH 8.4?…………..
    • A. 

      0,01

    • B. 

      0.5

    • C. 

      0.9

    • D. 

      1.0

  • 24. 
    The following is the example of cationic surfactant……………………
    • A. 

      Benzalkonium chloride

    • B. 

      Polysorbate 80

    • C. 

      SLS

    • D. 

      Sorbitan monooleate

  • 25. 
    The type of particle diameter that is obtained by microscopic method of evaluation is………………..
    • A. 

      Projected

    • B. 

      Stokes

    • C. 

      Volume

    • D. 

      Volume-surface

  • 26. 
    HEPA filters are widely used in ……………….. 
    • A. 

      Autoclaves

    • B. 

      Laminar air flow hoods

    • C. 

      Gas sterilizers

    • D. 

      Oxygen masks

  • 27. 
    Inversion sucrose in syrup due to heat is known as…………….
    • A. 

      Isomerization

    • B. 

      Epimerization

    • C. 

      Tautomeriation

    • D. 

      Caramelization

  • 28. 
    Carnauba wax is used in the following step of sugar coating of tablet:
    • A. 

      Seal coating

    • B. 

      Polishing

    • C. 

      Sub-coating

    • D. 

      Syrup coating

  • 29. 
    One of the following diluent may discolour in the presence of amine containing drugs:
    • A. 

      Avicel

    • B. 

      DCP

    • C. 

      Lactose

    • D. 

      Talc

  • 30. 
    Cam tracks are used in tablet formulation for………………
    • A. 

      Feeding the granules

    • B. 

      Fixing the shape

    • C. 

      Compressing the granules

    • D. 

      Guiding the movement of punches

  • 31. 
    Vit.requirement for microorganism Sytreptococcus pyogenes is……
    • A. 

      Tryptophan

    • B. 

      Glutathione

    • C. 

      Riboflavin

    • D. 

      Vit.B12

  • 32. 
    The test organism used for validation of filtration sterilization is……..
    • A. 

      Serratia marscenes

    • B. 

      Pseudomonas dimunata

    • C. 

      Vibrio percolans

    • D. 

      All of the above

  • 33. 
    The biological source for Cycloserine is…………
    • A. 

      S.Orchidaceus

    • B. 

      S.garyphyllus

    • C. 

      S.lavandulus

    • D. 

      All of the above

  • 34. 
    Which of the following drug used in digitalis induced arrhythmias?………….
    • A. 

      Verapamil

    • B. 

      Phenytoin

    • C. 

      Flecainide

    • D. 

      Procainamide

  • 35. 
    Aspartame is chemically…………….
    • A. 

      Methyl ester of aspartic acid and phenylalanine

    • B. 

      Methyl ester of phenylalanine and aspartic acid

    • C. 

      Ethyl ester of phenyl alanine and aspartic acid

    • D. 

      Ethyl ester of aspartic acid and phenyl alanine

  • 36. 
    • A. 

      UV-visible detector

    • B. 

      Diode array detector

    • C. 

      Refractive index detector

    • D. 

      Fluorescence detector

  • 37. 
    • A. 

      Pilocarpus

    • B. 

      Asthma weed

    • C. 

      Aconite

    • D. 

      Holarhhena

  • 38. 
    Sugar coated tablet having disintegration time is……………
    • A. 

      15 min

    • B. 

      60 min

    • C. 

      30 min

    • D. 

      45 min

  • 39. 
    Drugs used in the treatment of Insulinoma is……………
    • A. 

      Chlorambucil

    • B. 

      Tolbutamide

    • C. 

      Streptozotocin

    • D. 

      Melphalan

  • 40. 
    Which of the following used as stabilizer in the parenteral products………..?
    • A. 

      Na sulfate

    • B. 

      Na caprylate

    • C. 

      SNa desoxycholate

    • D. 

      Na CMC

  • 41. 
    Most commonly used radiation source in atomic absorption spectroscopy is…………….
    • A. 

      Tungsten lamp

    • B. 

      Xenon discharge lamp

    • C. 

      Hollow cathode lamp

    • D. 

      Mercury vapour lamp

  • 42. 
    Anorgasmia side effect produced by…………..
    • A. 

      Selective serotonin reuptake inhibitor

    • B. 

      Tricyclic antidepressant

    • C. 

      Monoamine oxidase inhibitors

    • D. 

      All of the above

  • 43. 
    Which of the following drug is contraindicated in type IIa hyperlipoproteinamia……….?
    • A. 

      Probucol

    • B. 

      Colestipol

    • C. 

      Acipimox

    • D. 

      Fish oil

  • 44. 
    Mediastinal fibrosis side effects produced by……………..
    • A. 

      Propranolol

    • B. 

      Sumatriptan

    • C. 

      Methysergide

    • D. 

      Cyproheptadine

  • 45. 
    Number of peaks given by 1H NMR spectrum of P-xylene is…………..
    • A. 

      4

    • B. 

      1

    • C. 

      2

    • D. 

      3

  • 46. 
    USP dissolution apparatus 4 used for ……………
    • A. 

      Capsule

    • B. 

      Tablet

    • C. 

      Low solubility of drugs

    • D. 

      Emulsion

  • 47. 
    • A. 

      9

    • B. 

      12-A

    • C. 

      11-A

    • D. 

      24-A

  • 48. 
    Paper chromatography is based on…………….
    • A. 

      Adsorption

    • B. 

      Exclusion

    • C. 

      Affinity

    • D. 

      Partition

  • 49. 
    Which transitions are given by benzoic acid under UV spectra………………
    • A. 

      N π*

    • B. 

      π π*

    • C. 

      N δ*

    • D. 

      δ δ*

  • 50. 
    In a formulation laboratory , tablet is to be formulated,the core tablet has bad taste and required protection from moisture.The Tablet should also deliver the drug for local action in intestine:Suggest suitable method………
    • A. 

      Sugar coating

    • B. 

      Film coating

    • C. 

      Enteric coating

    • D. 

      Sub-coating