Salivary Gland Pathology
Tumors of salivary glands
- 1.
The normal histology of salivary glands includes
- A.
Endocrine glands secreting salivary amyase
- B.
Acini consisting of only mucinus components
- C.
Mucinus squamoid epithelia aligned in stratified layers along intercalated ducts
- D.
Compound exocrine glands with ductal and acinar portions
Correct Answer
D. Compound exocrine glands with ductal and acinar portions -
- 2.
A distinguishing histologic feature of the parotid gland includes
- A.
Lack of mucinous acini
- B.
Abundance of centroacinar cells
- C.
Lack of lymphoid tissue
- D.
Lack of adipose tissue
Correct Answer
A. Lack of mucinous acini -
- 3.
Where is salivary heterotopic tissue most likely to be found?
- A.
In the submandibular lymph nodes
- B.
Near the parotid gland; in the medullary portion of the node
- C.
Near the parotid gland; in the extra nodal space
- D.
Along the medial border of the sternocleidomastoid muscle
- E.
At the root of the tongue in the floor of the mouth
Correct Answer
C. Near the parotid gland; in the extra nodal space -
- 4.
In diffuse infiltrative lymphocytosis syndrome, which histologic feature is most likely predominant?
- A.
CD8+ lymphocytic infiltrate with or without salivary ductal epithelial atypia
- B.
Macrophages and mutlinucleated giant cells in a vascular region of lipid debris and fibrous tissue
- C.
Neutrophilic incursion with necrosis and hemorrhage in lymphoid subcapsular spaces
- D.
Subcapsular fibrosis with and infiltrate of plasma cells and activated macrophages
- E.
Salivary ductal epithelial atypia with rare intraepithelial and intraacinar lymphocytes
Correct Answer
A. CD8+ lymphocytic infiltrate with or without salivary ductal epithelial atypia -
- 5.
A 35 year old HIV positive female presents with slow bilateral enlargement of her salivary and lacrimal glands. Microscopically, marked lymphocytic infiltration with lymphoid follicles surrounding solid epithelial nests are seen. What is the most likely diagnosis?
- A.
Diffuse large B cell lymphoma
- B.
Salivary lymphoid follicular hyperplasia
- C.
Lymphoepithelial sialadenitis
- D.
Adenomatous ductal hyperplasia
- E.
Mikulicz’s disease
Correct Answer
E. Mikulicz’s disease -
- 6.
A 50 year old man presents with unilateral, painful enlargement of salivary gland. The cause of this entity is most likely due to?
- A.
Obstruction of a salivary duct orifice and subsequent Staphalococcus aureus infection
- B.
Infiltration of interfollicular region by monocytoid cells and atypical plasma cells containing Dutcher bodies
- C.
Overproduction of serous fluid by parotid acini with concurrent edema and swelling of the parotid gland(s)
- D.
Nodular lymphoid neoplasm along the angle of the mandible
- E.
Diffuse lymphoid follicular hyperplasia in and around the submandibular gland
Correct Answer
A. Obstruction of a salivary duct orifice and subsequent Staphalococcus aureus infection -
- 7.
Chronic sialadenitis is characterized by
- A.
Lymphoplasmacytic periductal infiltrate leading to encasement of ducts in thick fibrous tissue
- B.
Chronic lymphocytic inflammation, often without symptoms
- C.
Apocrine metaplasia and transluminal bridges with cribriform growth
- D.
Prominent epithelial atypia
- E.
Granuloma formation with predominant multi-nucleated giant cells
Correct Answer
B. Chronic lymphocytic inflammation, often without symptoms -
- 8.
Sialolithiasis is most common in which gland?
- A.
Parotid
- B.
Submandibular
- C.
Lacrimal
- D.
Minor salivary glands within the hard palate
Correct Answer
B. Submandibular -
- 9.
What is the most common salivary gland tumor of infants/children?
- A.
Pleomorphic adenoma
- B.
Undifferentiated B cell lymphoma
- C.
Hemangioendothelioma
- D.
Juvenile mucoepidermoid carcinoma
- E.
Acinar carcinoma with myoepithelioid elements
Correct Answer
C. Hemangioendothelioma -
- 10.
45 year old male smoker presents with a slow growing facial mass that flucuates in size, what is the most likely microscopic description?
- A.
Squamoid cells mixed with proliferative tufts of fibrous stroma
- B.
Cystic spaces narrowed by polypoid projections of lymphoepithelial elements
- C.
Well-formed ducts and tubules with central lumina lined by inner epithelial and outer myoepithelial cells
- D.
Atypical squamous cells with perineural invasion
- E.
Gland proliferation within tufts of proliferative fibrous stroma
Correct Answer
B. Cystic spaces narrowed by polypoid projections of lymphoepithelial elements -
- 11.
The above tumor was "shelled out", leaving residual projections of tumor in the site. What is the most likely chance of recurrence?
- A.
2-5%
- B.
12-15%
- C.
25%
- D.
35%
- E.
50-75%
- F.
Less than 1%
Correct Answer
A. 2-5% -
- 12.
Most common lymphoma originating within or adjacent to salivary glands?
- A.
T cell lymphoma
- B.
Hodgkin lymphoma
- C.
Mantle cell lymphoma
- D.
MALT lymphoma
- E.
Diffuse undifferentiated B cell lymphoma
Correct Answer
D. MALT lymphoma -
- 13.
The above entity is most likely to be associated with which condition?
- A.
Sjorgen syndrome
- B.
HIV
- C.
EBV
- D.
Granulomatous sialadenitis
- E.
Reactive follicular hyperplasia of undetermined significance
Correct Answer
A. Sjorgen syndrome -
- 14.
A SCC in the parotid gland is most likely derived from?
- A.
Primary source
- B.
SCC from lung
- C.
Primary supraglottic SCC
Correct Answer
C. Primary supraglottic SCC -
- 15.
A nonencapsulated but well circumscribed tumor with diverse growth patterns, infiltrative borders Proliferative mucoid and hyaline stroma. Tumor cells have only mild atypia with uniform, bland nuclei.
- A.
Mucoepidermoid carcinoma
- B.
Pleomorphic adenoma
- C.
Polymorphous low grade adenocarcinoma
- D.
MALT lymphoma
- E.
Squamous cell carcinoma
Correct Answer
C. Polymorphous low grade adenocarcinoma -
- 16.
The entity above is most likely to arise in?
- A.
Parotid gland
- B.
Hard palate
- C.
Submandibular gland
- D.
Sub lingual gland
- E.
Lacrimal gland
- F.
Sub-glottic space
- G.
Floor of the mouth
Correct Answer
B. Hard palate -
- 17.
34 year old woman presents with a painless, slow growing mass on the left side of her face. What is the most likely diagnosis?
- A.
Pleomorphic adenoma
- B.
Warthin tumor
- C.
Polymorphous low grade adenocarcinoma
- D.
Mucoepidermoid
- E.
MALT lymphoma
Correct Answer
A. Pleomorphic adenoma -
- 18.
What is the most common radiation induced neoplasm of the salivary glands?
- A.
Pleomorphic adenoma
- B.
Polymorphous low grade adenocarcinoma
- C.
Mucoepidermoid carcinoma
- D.
Adenosquamous carcinoma
- E.
Acinar gland carcinoma
Correct Answer
C. Mucoepidermoid carcinoma -
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Nov 15, 2018Quiz Edited by
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Jun 29, 2011Quiz Created by
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