Quantiferon Rep Quiz # 2

10 Questions | Total Attempts: 69

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Quantiferon Rep Quiz # 2

On-boarding knowledge survey for weeks 4-6.


Questions and Answers
  • 1. 
    In the Diel study “Evidence-based Comparison of Commercial Interferon-gamma Release Assays for Detecting Active Tuberculosis -- a Meta-Analysis,” select the appropriate value for the TSpot cut-off used to be considered for a positive result? 
    • A. 

      10 spots

    • B. 

      3 spots

    • C. 

      > or equal to 6 spots

    • D. 

      Less than or equal to 5 spots

  • 2. 
    In the Diel study mentioned above, there were only ___ of the 679 obtained papers met the inclusion criteria for this meta-analysis.
    • A. 

      124 publications

    • B. 

      412 publications

    • C. 

      214 publications

    • D. 

      142 publications

  • 3. 
    Of the 2 U.S. commercially-available IGRAs, which one had a higher pooled sensitivity.
    • A. 

      T-Spot

    • B. 

      QuantiFERON-TB Gold

  • 4. 
    The Negative Predictive Value (NPV) for the QFT in the Diel study was 98%.
    • A. 

      True

    • B. 

      False

  • 5. 
    CDC recommends either TST or an IGRA for screening immigrant children age ___  from high risk countries.
    • A. 

      2-14 years

    • B. 

      < 5 years

    • C. 

      >15 years

    • D. 

      None of the above.

  • 6. 
    Of the available LTBI blood tests, which test demonstrated a better performance trend in BCG-vaccinated children?
    • A. 

      TST

    • B. 

      QFT

    • C. 

      T-Spot

    • D. 

      None of the above.

  • 7. 
    In Starke’s article “Interferon-γ Release Assays for Diagnosis of Tuberculosis Infection and Disease in Children,” about 50% infants who received a BCG-vaccine will respond with a significant induration to a TST.
    • A. 

      True

    • B. 

      False

  • 8. 
    IGRAs are the "Gold Standard" for active TB testing.
    • A. 

      True

    • B. 

      False

  • 9. 
    Which diagnostic assay has the least amount of subjectivity in diagnosing latent TB infection?
    • A. 

      QFT-TB Gold

    • B. 

      TST

    • C. 

      T-Spot

    • D. 

      None of the above.

  • 10. 
    False-negative TST results can occur when children suffer from severe active TB or immune suppression. 
    • A. 

      True

    • B. 

      False

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