Cytochromes Quiz: How Much Do You Know About Cytochromes?

38 Questions | By Themes | Updated: Mar 18, 2022 | Attempts: 33

Questions

Settings

Cytochromes Quiz: How Much Do You Know About Cytochromes? - Quiz

Are you a big fan of enzymology (the study of enzymes)? This quiz is about a certain type of enzyme known as Cytochrome. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. CYPs are, in general, the terminal oxidase enzymes in electron transfer chains, usually categorized as P450-containing systems. Know more about enzymes and cytochromes in this quiz.

Questions and Answers

1.

What CYP(s) does cimetidine INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
2.

What CYP(s) does amiodarone INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
3.

What CYPs do the -azoles INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
4.

What CYP(s) does ritonavir INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
5.

What CYP(s) does tacrolimus INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
6.

What CYP(s) does tamoxifen INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
7.

What CYP(s) does fluvoxamine INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
8.

What CYP(s) does erythromycin INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
9.

What CYP(s) does fluoxetine INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
10.

What CYP(s) does paroxetine INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
11.

What CYP(s) does St. Johns wort INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
12.

What CYP(s) does barbiturates INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
13.

What CYP(s) does rifampin INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
14.

What CYP(s) does carbamazepine INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
15.

What CYP(s) does phenytoin INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
16.

What CYP(s) does dexamethasone INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
17.

What CYP(s) does phenobarbital INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
18.

What CYP(s) does apalutamide INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
19.

What CYP(s) does modafanil INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
20.

What CYP(s) does primidone INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
21.

What CYP(s) does metronidazole INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
22.

What CYP(s) does haloperidol INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
23.

What CYP(s) does omeprazole INDUCE?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
24.

What CYP(s) does omeprazole INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4
25.

What CYP(s) does verapamil INHIBIT?
- A.
  
  PgP
- B.
  
  CYP1A2
- C.
  
  CYP2C8
- D.
  
  CYP2D6
- E.
  
  CYP2C9
- F.
  
  CYP2C19
- G.
  
  CYP3A4