Cytochromes Quiz: How Much Do You Know About Cytochromes?

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Cytochromes Quiz: How Much Do You Know About Cytochromes?

Are you a big fan of enzymology (the study of enzymes)? This quiz is about a certain type of enzyme known as Cytochrome. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. CYPs are, in general, the terminal oxidase enzymes in electron transfer chains, usually categorized as P450-containing systems. Know more about enzymes and cytochromes in this quiz.

Questions and Answers
  • 1. 
    What CYP(s) does cimetidine INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 2. 
    What CYP(s) does amiodarone INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 3. 
    What CYPs do the -azoles INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 4. 
    What CYP(s) does ritonavir INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 5. 
    What CYP(s) does tacrolimus INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 6. 
    What CYP(s) does tamoxifen INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 7. 
    What CYP(s) does fluvoxamine INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 8. 
    What CYP(s) does erythromycin INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 9. 
    What CYP(s) does fluoxetine INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 10. 
    What CYP(s) does paroxetine INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 11. 
    What CYP(s) does St. Johns wort INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 12. 
    What CYP(s) does barbiturates INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 13. 
    What CYP(s) does rifampin INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 14. 
    What CYP(s) does carbamazepine INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 15. 
    What CYP(s) does phenytoin INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 16. 
    What CYP(s) does dexamethasone INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 17. 
    What CYP(s) does phenobarbital INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 18. 
    What CYP(s) does apalutamide INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 19. 
    What CYP(s) does modafanil INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 20. 
    What CYP(s) does primidone INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 21. 
    What CYP(s) does metronidazole INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 22. 
    What CYP(s) does haloperidol INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 23. 
    What CYP(s) does omeprazole INDUCE?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 24. 
    What CYP(s) does omeprazole INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

  • 25. 
    What CYP(s) does verapamil INHIBIT?
    • A. 

      PgP

    • B. 

      CYP1A2

    • C. 

      CYP2C8

    • D. 

      CYP2D6

    • E. 

      CYP2C9

    • F. 

      CYP2C19

    • G. 

      CYP3A4

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