Play This Quiz And Learn About Pharmacology.

54 Questions | Total Attempts: 49

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Play This Quiz And Learn About Pharmacology.

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Questions and Answers
  • 1. 
    Afterload is determined by the
    • A. 

      Aortic diastolic pressure

    • B. 

      Aortic systolic pressure

    • C. 

      Pressure that distends the ventricular wall during diastole

    • D. 

      Pressure that distends the atrial wall during diastole

  • 2. 
    Prinzmetal's Angina is treated by reducing vasospasm
    • A. 

      True

    • B. 

      False

  • 3. 
    The Subendocardial regions of the heart are _______ perfused than the subepicardial regions
    • A. 

      Equally

    • B. 

      More

    • C. 

      Less

  • 4. 
    The right ventricle and inner muscle are more susceptible to ischemic damage during an MI
    • A. 

      True

    • B. 

      False

  • 5. 
    Nitrates are converted to Nitric Oxide to result in the formation of cGMP. Cyclic GMP then does what?
    • A. 

      Increases Calcium to selectively dilate veins

    • B. 

      Decreases Calcium to selectively dilate arteries

    • C. 

      Dephosphorylate Myosin Light Chains to selectively dilate Veins

    • D. 

      Dephosphorylate Myosin Light Chains to selectively dilate arteries

  • 6. 
    Organic nitrates directly lower inotropy and chronotropy
    • A. 

      True

    • B. 

      False

  • 7. 
    Tolerance is rare with Sublingual Nitrates
    • A. 

      True

    • B. 

      False

  • 8. 
    Oral (not sublingual) and transdermal Nitro's:
    • A. 

      Have a relatively quick onset and short DOA

    • B. 

      Are used for acute attacks

    • C. 

      Are used for prophylaxis

    • D. 

      Are given in high doses saturate the liver's capacity to degrade them.

    • E. 

      B and C

    • F. 

      C and D

    • G. 

      B C and D

    • H. 

      All of the above

  • 9. 
    Selective filtration in the glomerulus only filters small molecules
    • A. 

      True

    • B. 

      False

  • 10. 
    On the countercurrent exchange in a hairpin loop in the medulla it is saltier on the _______ limb than the ________ limb so water leaves the _____ loop
    • A. 

      Descending, ascending, ascending

    • B. 

      Descending, ascending, descending

    • C. 

      Ascending, descending, ascending

    • D. 

      Ascending, descending, descending

  • 11. 
    If ADH is absent, we excrete our maximally dilute urine, approximately equal to the plasma osmolality
    • A. 

      True

    • B. 

      False

  • 12. 
    This diuretic takes up to 48 hours to begin its work, has slow offset, and Side Effects include hyperkalemia and gynecomastia
    • A. 

      Hydrochlorothiazide

    • B. 

      Chlorthalidone

    • C. 

      Amiloride

    • D. 

      Spironolactone

  • 13. 
    Use this diuretic to offset the lithium toxicity of Na/K exchange
    • A. 

      Hydrochlorothiazide

    • B. 

      Furosemide

    • C. 

      Triamterene

    • D. 

      Spironolactone

  • 14. 
    This diuretic does not work well with low RBF and GFR. Counseling on this drug should include "Do not take before bedtime"
    • A. 

      Hydrochlorothiazide

    • B. 

      Furosemide

    • C. 

      Amiloride

    • D. 

      Spironolactone

  • 15. 
    Hydrochlorothiazide decreases Ca2+ excretion while Furosemide increases Ca2+ excretion.
    • A. 

      True

    • B. 

      False

  • 16. 
    This Diuretic can cause Side effects of -- ototoxicity, digoxin toxicity and increased Kidney stone risk. It's effects are also antagonized by NSAIDs.
    • A. 

      Hydrochlorothiazide

    • B. 

      Furosemide

    • C. 

      Spironolactone

    • D. 

      Amiloride

  • 17. 
    This Diuretic, used for glaucoma, works by inhibiting carbonic anhydrase.
    • A. 

      Bumetanide

    • B. 

      Furosemide

    • C. 

      Mannitol

    • D. 

      Acetazolamide

  • 18. 
    This Diuretic eliminates excess intracellular edema and is used for prophylaxis of renal failure to keep fluid volume in the tubules to prevent them from collapsing.
    • A. 

      Ethacrynic Acid

    • B. 

      Torsemide

    • C. 

      Mannitol

    • D. 

      Vaptans

  • 19. 
    NSAIDs can antagonize the antihypertensive effects of diuretics
    • A. 

      True

    • B. 

      False

  • 20. 
    Conductance is a measure of how much _______ moves in
    • A. 

      Na+

    • B. 

      K+

    • C. 

      Ca2+

    • D. 

      None of the above

  • 21. 
    This drug, originated from the toxin of a snail,  is the only to block N-type Calcium Channels to block pain perception
    • A. 

      Ziconotide

    • B. 

      Verapamil

    • C. 

      Nifedipine

    • D. 

      Isradipine

  • 22. 
    Verapamil and Nifedipine increase the refractory period of cardiac cells.
    • A. 

      True

    • B. 

      False

  • 23. 
    This drug has negative inotropic effects with decreased afterload but causes reflex tachycardia resulting in an increase in CO.
    • A. 

      Verapamil

    • B. 

      Diltiazem

    • C. 

      Nifedipine

    • D. 

      Ziconotide

  • 24. 
    Beta Blockers antagonize the actions epinephrine and norepinephrine resulting in decreased force, rate, conduction and work
    • A. 

      True

    • B. 

      False

  • 25. 
    All of the following are true except: the three major determinants of myocardial oxygen demand that are reduced by beta blockers are:
    • A. 

      Heart rate

    • B. 

      Contractility

    • C. 

      Systolic wall tension

    • D. 

      Diastolic wall tension

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