Pharmacology Exam 3 Practice I

32 Questions | Total Attempts: 71

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Pharmacology Exam 3 Practice I

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Questions and Answers
  • 1. 
    Which is not a possible cause of clot formation?
    • A. 

      Atrial fibrillation

    • B. 

      Bed rest

    • C. 

      Heart Attack

    • D. 

      Vascular Injury

    • E. 

      Paralysis

    • F. 

      All of the above are possible causes

  • 2. 
    Contact of blood with collagen starts the extrinsic pathway
    • A. 

      True

    • B. 

      False

  • 3. 
    Which is not an anticoagulant that catalyzes antithrombin?
    • A. 

      Enoxaparin

    • B. 

      Fondaparinux

    • C. 

      Rivaroxaban

    • D. 

      Heparin

  • 4. 
    Heparin has lipid clearing activity due to the release of lipoprotein hydrolase
    • A. 

      True

    • B. 

      False

  • 5. 
    Which are acceptable dosage forms for Heparin?
    • A. 

      IM

    • B. 

      IV

    • C. 

      Oral

    • D. 

      Subcutaneous (deep fat)

  • 6. 
    What is false about protamine treatment?
    • A. 

      It is dosed 1:2 to heparin

    • B. 

      It may cause anaphylactic shock because it is derived from fish sperm

    • C. 

      Dosage form is based on the level of heparin

    • D. 

      It is a treatment for heparin toxicity

  • 7. 
    Which is not a low molecular weight heparin?
    • A. 

      Enoxaparin

    • B. 

      Fondaparinux

    • C. 

      Dalteparin

    • D. 

      Tinzaparin

    • E. 

      Argatroban

  • 8. 
    Dabigatran is a direct thrombin inhibitor
    • A. 

      True

    • B. 

      False

  • 9. 
    Dabigatran etexilate is indicated to prevent strokes in patients with: 
  • 10. 
    Which is a warfarin synergist?
    • A. 

      Barbiturates

    • B. 

      Thyroid

    • C. 

      Estrogens

    • D. 

      Rifampin

    • E. 

      Vitamin K

  • 11. 
    Which is false about alteplase?
    • A. 

      Activates fibrin-bound plasminogen

    • B. 

      It is extremely antigenic

    • C. 

      It has a short half-life and 90 minute infusion

    • D. 

      There is an increased intracranial bleeding risk

  • 12. 
    Which is true about clopidogrel?
    • A. 

      Activated by CYP3A4

    • B. 

      Indicated for thrombosis & coronary artery disease

    • C. 

      High risk for TTP - thrombotic thrombocytopenia purpura

    • D. 

      Not recommended for patients allergic to aspirin

  • 13. 
    Ticagrelor is co-administered with aspirin >100 mg
    • A. 

      True

    • B. 

      False

  • 14. 
    Which are synthetic forms of platelet glycoprotien IIb/IIIa receptor antagonists?
    • A. 

      Abciximab

    • B. 

      Eptifibatide

    • C. 

      Tirofiban

    • D. 

      Chloroxibatide

  • 15. 
    Dipyridamole and this other drug are combined in one dosage form for use in patients with prosthetic heart valves. 
    • A. 

      Aspirin

    • B. 

      Cilostazol

    • C. 

      None - it is administered alone

  • 16. 
    These are the largest particles of low density
    • A. 

      LDL

    • B. 

      VLDL

    • C. 

      Chylomicrons

    • D. 

      IDL

    • E. 

      HDL

  • 17. 
    VLDLs function to transport free fatty acids from the peripheral tissues to the liver.
    • A. 

      True

    • B. 

      False

  • 18. 
    IDL is formed from the HDL hydrolysis of triglycerides from VLDL
    • A. 

      True

    • B. 

      False

  • 19. 
    Which is the major apolopoprotein of LDL?
    • A. 

      CII

    • B. 

      CII

    • C. 

      B-100

    • D. 

      AI

    • E. 

      E

  • 20. 
    AIV is recognized by a scavenger receptor (SR-BI) on the liver, which takes HDL into the liver.
    • A. 

      True

    • B. 

      False

  • 21. 
    Lipoprotein A is a marker for heart disease
    • A. 

      True

    • B. 

      False

  • 22. 
    Desirable total blood cholesterol levels are <250 mg/dL
    • A. 

      True

    • B. 

      False

  • 23. 
    Which is the drug of choice for lowering VLDL in patients at risk of pancreatitis?
    • A. 

      Niaspan

    • B. 

      Fenofibrate

    • C. 

      Gemfibrozil

    • D. 

      Simvastatin

  • 24. 
    Niaspan/Niacin/Nicotinic acid is mose efective when given with other drugs.
    • A. 

      True

    • B. 

      False

  • 25. 
    Which may lower LDL levels more effectively?
    • A. 

      Gemfibrozil

    • B. 

      Fenofibrate

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